STRINGSTRING
LOC102353790 LOC102353790 JAG1 JAG1 FKBP10 FKBP10 GJA5 GJA5 NOTCH3 NOTCH3 HAND2 HAND2 PKD2 PKD2 ARID2 ARID2 ANGPTL3 ANGPTL3 EDNRA EDNRA SMAD7 SMAD7 SEC24B SEC24B FGF8 FGF8 NPRL3 NPRL3 TGFBR1 TGFBR1 H3APB2_LATCH H3APB2_LATCH DLL4 DLL4 MYOCD MYOCD SRF SRF HPGD-2 HPGD-2 BMPR2 BMPR2 EDN1 EDN1 NF1 NF1 H3BCG1_LATCH H3BCG1_LATCH HOXA13 HOXA13 H3BEX6_LATCH H3BEX6_LATCH LOC102348458 LOC102348458 ACVRL1 ACVRL1 HPGD HPGD APOB APOB ENG ENG STRA6 STRA6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102353790Uncharacterized protein. (899 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1220 aa)
FKBP10Peptidylprolyl isomerase. (450 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (371 aa)
NOTCH3Notch receptor 3. (1577 aa)
HAND2Heart and neural crest derivatives expressed 2. (210 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (890 aa)
ARID2AT-rich interaction domain 2. (1771 aa)
ANGPTL3Angiopoietin like 3. (454 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1197 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (396 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
H3APB2_LATCHFork-head domain-containing protein. (408 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (688 aa)
MYOCDMyocardin. (963 aa)
SRFSerum response factor. (520 aa)
HPGD-2Uncharacterized protein. (86 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
EDN1Endothelin 1. (216 aa)
NF1Neurofibromin 1. (2814 aa)
H3BCG1_LATCHSET domain-containing protein. (714 aa)
HOXA13Homeobox A13b. (295 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
LOC102348458Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (497 aa)
HPGD15-hydroxyprostaglandin dehydrogenase. (165 aa)
APOBApolipoprotein B. (4644 aa)
ENGEndoglin. (674 aa)
STRA6Stimulated by retinoic acid 6. (664 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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