STRINGSTRING
NCAPG2 NCAPG2 SMO SMO EPAS1 EPAS1 GATA3 GATA3 UBAP2L UBAP2L NAPEPLD NAPEPLD CARD11 CARD11 LOC102358239 LOC102358239 SOS1 SOS1 KIT KIT ATP5IF1 ATP5IF1 H2ZSI1_LATCH H2ZSI1_LATCH RC3H2 RC3H2 GLIS2 GLIS2 ABCB10 ABCB10 NLE1 NLE1 RB1 RB1 CCR8 CCR8 PRDM14 PRDM14 CEBPG CEBPG PTPN2 PTPN2 TNFSF13B TNFSF13B LYN LYN SLC25A38 SLC25A38 JAK2 JAK2 LGALS2 LGALS2 BAX BAX CASP3 CASP3 UBAP2 UBAP2 CCN3 CCN3 H3AES2_LATCH H3AES2_LATCH SMAD5 SMAD5 FH FH SART3 SART3 SOS2 SOS2 CDK5RAP3 CDK5RAP3 GPAM GPAM H3AHE4_LATCH H3AHE4_LATCH PKNOX1 PKNOX1 H3AHJ4_LATCH H3AHJ4_LATCH IL6 IL6 KCNQ1 KCNQ1 FADD FADD CAMLG CAMLG UBA5 UBA5 GATA1 GATA1 LOC102346566 LOC102346566 H3AKR5_LATCH H3AKR5_LATCH HSPA9 HSPA9 H3AM65_LATCH H3AM65_LATCH UFL1 UFL1 MERTK MERTK NCSTN NCSTN ZBTB7A ZBTB7A SP3 SP3 RCOR1 RCOR1 LOC102358329 LOC102358329 LRRC45 LRRC45 LOC102359041 LOC102359041 GCNT4 GCNT4 LOC102354453 LOC102354453 TAL1 TAL1 MED1 MED1 JAM3 JAM3 IKZF1 IKZF1 TRAF3IP2 TRAF3IP2 LGR4 LGR4 SCNN1B SCNN1B LRRC19 LRRC19 LOC102355766 LOC102355766 LOC102367521 LOC102367521 LOC102359313 LOC102359313 SLC40A1 SLC40A1 NKX2-3 NKX2-3 SH2B3 SH2B3 CCR7 CCR7 JMJD6 JMJD6 LOC102363504 LOC102363504 SASH3 SASH3 ERCC2 ERCC2 ALAS2 ALAS2 SRF SRF FSTL1 FSTL1 NKX2-6 NKX2-6 TNFAIP3 TNFAIP3 POLB POLB SKIL SKIL SLC46A2 SLC46A2 HOXB6 HOXB6 ACIN1 ACIN1 KMT2E KMT2E H3B8Q8_LATCH H3B8Q8_LATCH BAK1 BAK1 VPS54 VPS54 RC3H1 RC3H1 DMTN DMTN DOCK10 DOCK10 NF1 NF1 CARD9 CARD9 LOC102354477 LOC102354477 PPP2R3C PPP2R3C AXL AXL TGFB1 TGFB1 ZFPM1 ZFPM1 SPNS2 SPNS2 H3BHG1_LATCH H3BHG1_LATCH ALAS1 ALAS1 H2ZU41_LATCH H2ZU41_LATCH ARID4A ARID4A H3BI75_LATCH H3BI75_LATCH ADAR ADAR M3XHJ5_LATCH M3XHJ5_LATCH GPI GPI MFHAS1 MFHAS1 LYAR LYAR C15orf41 C15orf41 LOC102356247 LOC102356247 MAEA MAEA EPO EPO MYCT1 MYCT1 G6PD G6PD SLC37A4 SLC37A4 H2ZV40_LATCH H2ZV40_LATCH KLHL10 KLHL10 LPCAT3 LPCAT3 GPR183 GPR183
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCAPG2Non-SMC condensin II complex subunit G2. (1154 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (820 aa)
EPAS1Endothelial PAS domain protein 1. (861 aa)
GATA3GATA binding protein 3. (447 aa)
UBAP2LUbiquitin associated protein 2 like. (1109 aa)
NAPEPLDN-acyl phosphatidylethanolamine phospholipase D. (263 aa)
CARD11Caspase recruitment domain family member 11. (1137 aa)
LOC102358239TRAF3 interacting protein 2-like. (392 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1331 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (937 aa)
ATP5IF1ATP synthase inhibitory factor subunit 1a. (110 aa)
H2ZSI1_LATCHLisH domain-containing protein. (105 aa)
RC3H2RING-type domain-containing protein. (352 aa)
GLIS2GLIS family zinc finger 2. (534 aa)
ABCB10ATP binding cassette subfamily B member 10. (723 aa)
NLE1Notchless homolog 1. (488 aa)
RB1Uncharacterized protein. (411 aa)
CCR8Chemokine (C-C motif) receptor 11.1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
PRDM14PR/SET domain 14. (599 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (397 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (122 aa)
LYNTyrosine-protein kinase. (515 aa)
SLC25A38Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (307 aa)
JAK2Tyrosine-protein kinase. (1152 aa)
LGALS2Galectin. (137 aa)
BAXUncharacterized protein. (223 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (290 aa)
UBAP2Ubiquitin associated protein 2. (996 aa)
CCN3Cellular communication network factor 3. (345 aa)
H3AES2_LATCHUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (354 aa)
SMAD5Mothers against decapentaplegic homolog. (467 aa)
FHFumarate hydratase. (491 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (720 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1241 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (519 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (854 aa)
H3AHE4_LATCHUncharacterized protein. (463 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
H3AHJ4_LATCHIon_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
IL6Uncharacterized protein. (149 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
FADDFas associated via death domain. (193 aa)
CAMLGCalcium modulating ligand. (307 aa)
UBA5Ubiquitin like modifier activating enzyme 5. (407 aa)
GATA1GATA binding protein 1b. (432 aa)
LOC102346566Annexin. (343 aa)
H3AKR5_LATCHSolute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (547 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (647 aa)
H3AM65_LATCHMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (472 aa)
UFL1UFM1 specific ligase 1. (792 aa)
MERTKMER proto-oncogene, tyrosine kinase. (897 aa)
NCSTNNicastrin. (680 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (518 aa)
SP3Sp3 transcription factor. (785 aa)
RCOR1REST corepressor 1. (272 aa)
LOC102358329TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (161 aa)
LRRC45Leucine rich repeat containing 45. (679 aa)
LOC102359041Zgc:153993. (208 aa)
GCNT4Glucosaminyl (N-acetyl) transferase 4. (443 aa)
LOC102354453Uncharacterized protein. (230 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (327 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1401 aa)
JAM3Junctional adhesion molecule 3. (208 aa)
IKZF1IKAROS family zinc finger 1. (468 aa)
TRAF3IP2SEFIR domain-containing protein. (379 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (955 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (650 aa)
LRRC19Leucine rich repeat containing 19. (344 aa)
LOC102355766Uncharacterized protein. (524 aa)
LOC102367521Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
LOC102359313Uncharacterized protein. (334 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (583 aa)
NKX2-3NK2 homeobox 3. (334 aa)
SH2B3SH2B adaptor protein 3. (583 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (403 aa)
LOC102363504Tyrosine-protein kinase. (1116 aa)
SASH3SAM and SH3 domain containing 3. (433 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (611 aa)
ALAS25-aminolevulinate synthase. (615 aa)
SRFSerum response factor. (520 aa)
FSTL1Follistatin like 1. (261 aa)
NKX2-6Homeobox domain-containing protein. (322 aa)
TNFAIP3TNF alpha induced protein 3. (785 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
SKILSKI like proto-oncogene. (691 aa)
SLC46A2Solute carrier family 46 member 2. (461 aa)
HOXB6Homeobox B6. (361 aa)
ACIN1SAP domain-containing protein. (1277 aa)
KMT2ELysine methyltransferase 2E. (1846 aa)
H3B8Q8_LATCHForkhead box A3. (414 aa)
BAK1BCL2 antagonist/killer 1. (239 aa)
VPS54VPS54 subunit of GARP complex. (980 aa)
RC3H1Ring finger and CCCH-type domains 1. (1123 aa)
DMTNDematin actin binding protein. (406 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2199 aa)
NF1Neurofibromin 1. (2814 aa)
CARD9Caspase recruitment domain family member 9. (567 aa)
LOC102354477Uncharacterized protein. (838 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (451 aa)
AXLAXL receptor tyrosine kinase. (872 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
ZFPM1Zinc finger protein, FOG family member 1. (1017 aa)
SPNS2Sphingolipid transporter 2. (362 aa)
H3BHG1_LATCHPhospholipase A(2). (145 aa)
ALAS15-aminolevulinate synthase. (642 aa)
H2ZU41_LATCHUncharacterized protein. (331 aa)
ARID4AAT-rich interaction domain 4A. (1297 aa)
H3BI75_LATCHUncharacterized protein. (110 aa)
ADARAdenosine deaminase RNA specific. (1150 aa)
M3XHJ5_LATCHUncharacterized protein. (158 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (555 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (635 aa)
LYARLy1 antibody reactive. (403 aa)
C15orf41Chromosome 15 open reading frame 41. (160 aa)
LOC102356247Uncharacterized protein. (636 aa)
MAEAMacrophage erythroblast attacher. (287 aa)
EPOErythropoietin. (179 aa)
MYCT1MYC target 1. (194 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
SLC37A4Solute carrier family 37 member 4. (441 aa)
H2ZV40_LATCHProtein kinase domain-containing protein. (266 aa)
KLHL10Kelch like family member 10. (606 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (430 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (363 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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