(20 nodes) Arachidonic acid secretion network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NMUR2	Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (398 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	LOC102352291	PA2c domain-containing protein. (319 aa)
	LOC102352528	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa)
	PLA2G4F	Phospholipase A2. (785 aa)
	PLA2G12A	Phospholipase A2 group XIIA. (192 aa)
	LOC102361922	Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family. (448 aa)
	PNPLA8	Patatin like phospholipase domain containing 8. (796 aa)
	LOC102346566	Annexin. (343 aa)
	PLA2G12B	Phospholipase A2 group XIIB. (201 aa)
	H3AU65_LATCH	Phospholipase A(2). (398 aa)
	H3AX69_LATCH	Phospholipase A(2). (120 aa)
	DRD4	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	PLA2G3	Phospholipase A2 group III. (449 aa)
	PLA2G1B	Phospholipase A(2). (152 aa)
	LOC102359454	Phospholipase A(2). (154 aa)
	H3BG59_LATCH	Uncharacterized protein. (162 aa)
	DRD2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
	H3BHG1_LATCH	Phospholipase A(2). (145 aa)
	H3BIC9_LATCH	Phospholipase A(2). (155 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DRD2	DRD4	ENSLACP00000020922	ENSLACP00000016532	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.731
DRD2	LOC102352528	ENSLACP00000020922	ENSLACP00000003648	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.616
DRD2	LOC102361922	ENSLACP00000020922	ENSLACP00000008239	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family.	0.901
DRD3	DRD4	ENSLACP00000002245	ENSLACP00000016532	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.742
DRD3	LOC102352528	ENSLACP00000002245	ENSLACP00000003648	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.590
DRD4	DRD2	ENSLACP00000016532	ENSLACP00000020922	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.731
DRD4	DRD3	ENSLACP00000016532	ENSLACP00000002245	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.742
DRD4	LOC102361922	ENSLACP00000016532	ENSLACP00000008239	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family.	0.607
H3AU65_LATCH	PLA2G12A	ENSLACP00000013186	ENSLACP00000006343	Phospholipase A(2).	Phospholipase A2 group XIIA.	0.757
H3AU65_LATCH	PNPLA8	ENSLACP00000013186	ENSLACP00000009996	Phospholipase A(2).	Patatin like phospholipase domain containing 8.	0.462
H3AX69_LATCH	H3BIC9_LATCH	ENSLACP00000014240	ENSLACP00000021650	Phospholipase A(2).	Phospholipase A(2).	0.910
H3AX69_LATCH	LOC102352291	ENSLACP00000014240	ENSLACP00000003255	Phospholipase A(2).	PA2c domain-containing protein.	0.905
H3AX69_LATCH	LOC102359454	ENSLACP00000014240	ENSLACP00000020874	Phospholipase A(2).	Phospholipase A(2).	0.903
H3AX69_LATCH	PLA2G12A	ENSLACP00000014240	ENSLACP00000006343	Phospholipase A(2).	Phospholipase A2 group XIIA.	0.974
H3AX69_LATCH	PLA2G12B	ENSLACP00000014240	ENSLACP00000012432	Phospholipase A(2).	Phospholipase A2 group XIIB.	0.905
H3AX69_LATCH	PLA2G1B	ENSLACP00000014240	ENSLACP00000020868	Phospholipase A(2).	Phospholipase A(2).	0.903
H3AX69_LATCH	PLA2G4F	ENSLACP00000014240	ENSLACP00000004886	Phospholipase A(2).	Phospholipase A2.	0.914
H3AX69_LATCH	PNPLA8	ENSLACP00000014240	ENSLACP00000009996	Phospholipase A(2).	Patatin like phospholipase domain containing 8.	0.462
H3BG59_LATCH	H3BHG1_LATCH	ENSLACP00000020880	ENSLACP00000021332	Uncharacterized protein.	Phospholipase A(2).	0.423
H3BG59_LATCH	LOC102352291	ENSLACP00000020880	ENSLACP00000003255	Uncharacterized protein.	PA2c domain-containing protein.	0.444