(26 nodes) Musculoskeletal movement network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CLN8	CLN8 transmembrane ER and ERGIC protein. (294 aa)
	TNNI3	Uncharacterized protein. (240 aa)
	STAC	SH3 and cysteine rich domain. (279 aa)
	R3HDM1	R3H domain containing 1. (1107 aa)
	H3AC16_LATCH	X-ray repair complementing defective repair in Chinese hamster cells 1. (649 aa)
	TNNI2	Troponin I2, fast skeletal type. (190 aa)
	SYNM	IF rod domain-containing protein. (1242 aa)
	LOC102353564	Uncharacterized protein. (161 aa)
	TNNI1	Troponin I1, slow skeletal type. (171 aa)
	VTI1A	Vesicle transport through interaction with t-SNAREs 1A. (214 aa)
	HOMER1	Homer scaffold protein 1. (367 aa)
	STAC2	SH3 and cysteine rich domain 2. (375 aa)
	LOC102345989	Uncharacterized protein. (92 aa)
	CCDC78	Coiled-coil domain containing 78. (573 aa)
	LOC102350553	Uncharacterized protein. (232 aa)
	CHRND	Cholinergic receptor nicotinic delta subunit. (525 aa)
	LOC102365660	Uncharacterized protein. (187 aa)
	LOC102366172	Uncharacterized protein. (183 aa)
	H3B8U3_LATCH	Serine/threonine-protein kinase TOR. (1418 aa)
	VPS54	VPS54 subunit of GARP complex. (980 aa)
	MTOR	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
	TNNC1	Troponin C type 1a (slow). (164 aa)
	H3BH85_LATCH	Uncharacterized protein. (164 aa)
	LOC102352170	Uncharacterized protein. (163 aa)
	R3HDM2	R3H domain containing 2. (971 aa)
	STAC3	SH3 and cysteine rich domain 3. (373 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3B8U3_LATCH	MTOR	ENSLACP00000018314	ENSLACP00000018843	Serine/threonine-protein kinase TOR.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.944
H3BH85_LATCH	LOC102350553	ENSLACP00000021256	ENSLACP00000016618	Uncharacterized protein.	Uncharacterized protein.	0.833
H3BH85_LATCH	LOC102353564	ENSLACP00000021256	ENSLACP00000011490	Uncharacterized protein.	Uncharacterized protein.	0.578
H3BH85_LATCH	TNNC1	ENSLACP00000021256	ENSLACP00000021191	Uncharacterized protein.	Troponin C type 1a (slow).	0.577
H3BH85_LATCH	TNNI1	ENSLACP00000021256	ENSLACP00000012324	Uncharacterized protein.	Troponin I1, slow skeletal type.	0.834
H3BH85_LATCH	TNNI2	ENSLACP00000021256	ENSLACP00000008372	Uncharacterized protein.	Troponin I2, fast skeletal type.	0.992
H3BH85_LATCH	TNNI3	ENSLACP00000021256	ENSLACP00000002734	Uncharacterized protein.	Uncharacterized protein.	0.834
LOC102345989	LOC102350553	ENSLACP00000015742	ENSLACP00000016618	Uncharacterized protein.	Uncharacterized protein.	0.415
LOC102345989	TNNI1	ENSLACP00000015742	ENSLACP00000012324	Uncharacterized protein.	Troponin I1, slow skeletal type.	0.415
LOC102345989	TNNI2	ENSLACP00000015742	ENSLACP00000008372	Uncharacterized protein.	Troponin I2, fast skeletal type.	0.415
LOC102345989	TNNI3	ENSLACP00000015742	ENSLACP00000002734	Uncharacterized protein.	Uncharacterized protein.	0.415
LOC102350553	H3BH85_LATCH	ENSLACP00000016618	ENSLACP00000021256	Uncharacterized protein.	Uncharacterized protein.	0.833
LOC102350553	LOC102345989	ENSLACP00000016618	ENSLACP00000015742	Uncharacterized protein.	Uncharacterized protein.	0.415
LOC102350553	LOC102352170	ENSLACP00000016618	ENSLACP00000021261	Uncharacterized protein.	Uncharacterized protein.	0.833
LOC102350553	LOC102353564	ENSLACP00000016618	ENSLACP00000011490	Uncharacterized protein.	Uncharacterized protein.	0.819
LOC102350553	TNNC1	ENSLACP00000016618	ENSLACP00000021191	Uncharacterized protein.	Troponin C type 1a (slow).	0.819
LOC102350553	TNNI2	ENSLACP00000016618	ENSLACP00000008372	Uncharacterized protein.	Troponin I2, fast skeletal type.	0.694
LOC102352170	LOC102350553	ENSLACP00000021261	ENSLACP00000016618	Uncharacterized protein.	Uncharacterized protein.	0.833
LOC102352170	LOC102353564	ENSLACP00000021261	ENSLACP00000011490	Uncharacterized protein.	Uncharacterized protein.	0.576
LOC102352170	TNNC1	ENSLACP00000021261	ENSLACP00000021191	Uncharacterized protein.	Troponin C type 1a (slow).	0.575