(33 nodes) Detection of mechanical stimulus network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KCNK4	Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (444 aa)
	PDZD7	PDZ domain containing 7. (505 aa)
	H2ZWF8_LATCH	Leucine-rich repeats and IQ motif containing 1. (1148 aa)
	H2ZYB6_LATCH	Uncharacterized protein. (324 aa)
	H3A0G5_LATCH	Uncharacterized protein. (2422 aa)
	PKD1	Polycystin 1, transient receptor potential channel interacting. (4241 aa)
	TMC2	Transmembrane channel-like protein. (908 aa)
	KIT	KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (937 aa)
	H3A478_LATCH	PDZ domain-containing protein. (297 aa)
	PJVK	Pejvakin. (355 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (890 aa)
	SERPINE2	Serpin family E member 2; Belongs to the serpin family. (403 aa)
	JUP	Junction plakoglobin. (694 aa)
	H3A9U0_LATCH	PDZ domain-containing protein. (234 aa)
	MKKS	McKusick-Kaufman syndrome. (575 aa)
	H3AHJ4_LATCH	Ion_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
	H3AIG1_LATCH	Uncharacterized protein. (317 aa)
	PTPRQ	Protein tyrosine phosphatase receptor type Q. (1795 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
	H3AK63_LATCH	Uncharacterized protein. (2103 aa)
	ADGRV1	Adhesion G protein-coupled receptor V1. (5847 aa)
	PIEZO1	Piezo-type mechanosensitive ion channel component. (2125 aa)
	PKDREJ	Polycystin family receptor for egg jelly. (2164 aa)
	PKD2L1	Polycystin 2 like 1, transient receptor potential cation channel. (741 aa)
	H3AU40_LATCH	Piezo-type mechanosensitive ion channel component. (2543 aa)
	TRPA1	Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1138 aa)
	PKD2L2	Polycystin 2 like 2, transient receptor potential cation channel. (589 aa)
	HPN	Hepsin; Belongs to the peptidase S1 family. (415 aa)
	H3B277_LATCH	Uncharacterized protein. (4290 aa)
	PIEZO2	Piezo-type mechanosensitive ion channel component. (2426 aa)
	LOC102365660	Uncharacterized protein. (187 aa)
	LOC102366172	Uncharacterized protein. (183 aa)
	CSRP3	Cysteine and glycine rich protein 3. (192 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRV1	H3A478_LATCH	ENSLACP00000010057	ENSLACP00000004449	Adhesion G protein-coupled receptor V1.	PDZ domain-containing protein.	0.543
ADGRV1	H3A9U0_LATCH	ENSLACP00000010057	ENSLACP00000006411	Adhesion G protein-coupled receptor V1.	PDZ domain-containing protein.	0.530
ADGRV1	H3AIG1_LATCH	ENSLACP00000010057	ENSLACP00000009432	Adhesion G protein-coupled receptor V1.	Uncharacterized protein.	0.543
ADGRV1	PDZD7	ENSLACP00000010057	ENSLACP00000000972	Adhesion G protein-coupled receptor V1.	PDZ domain containing 7.	0.873
ADGRV1	TMC2	ENSLACP00000010057	ENSLACP00000004291	Adhesion G protein-coupled receptor V1.	Transmembrane channel-like protein.	0.431
CSRP3	LOC102365660	ENSLACP00000018230	ENSLACP00000017843	Cysteine and glycine rich protein 3.	Uncharacterized protein.	0.546
CSRP3	LOC102366172	ENSLACP00000018230	ENSLACP00000017946	Cysteine and glycine rich protein 3.	Uncharacterized protein.	0.546
H3A0G5_LATCH	H3AK63_LATCH	ENSLACP00000003136	ENSLACP00000010034	Uncharacterized protein.	Uncharacterized protein.	0.410
H3A0G5_LATCH	H3B277_LATCH	ENSLACP00000003136	ENSLACP00000015998	Uncharacterized protein.	Uncharacterized protein.	0.410
H3A0G5_LATCH	PKD1	ENSLACP00000003136	ENSLACP00000004230	Uncharacterized protein.	Polycystin 1, transient receptor potential channel interacting.	0.410
H3A0G5_LATCH	PKD2	ENSLACP00000003136	ENSLACP00000004922	Uncharacterized protein.	Polycystin 2, transient receptor potential cation channel.	0.797
H3A0G5_LATCH	PKD2L1	ENSLACP00000003136	ENSLACP00000019679	Uncharacterized protein.	Polycystin 2 like 1, transient receptor potential cation channel.	0.954
H3A0G5_LATCH	PKD2L2	ENSLACP00000003136	ENSLACP00000015184	Uncharacterized protein.	Polycystin 2 like 2, transient receptor potential cation channel.	0.665
H3A0G5_LATCH	PKDREJ	ENSLACP00000003136	ENSLACP00000012062	Uncharacterized protein.	Polycystin family receptor for egg jelly.	0.410
H3A478_LATCH	ADGRV1	ENSLACP00000004449	ENSLACP00000010057	PDZ domain-containing protein.	Adhesion G protein-coupled receptor V1.	0.543
H3A478_LATCH	H3AIG1_LATCH	ENSLACP00000004449	ENSLACP00000009432	PDZ domain-containing protein.	Uncharacterized protein.	0.899
H3A478_LATCH	TMC2	ENSLACP00000004449	ENSLACP00000004291	PDZ domain-containing protein.	Transmembrane channel-like protein.	0.401
H3A9U0_LATCH	ADGRV1	ENSLACP00000006411	ENSLACP00000010057	PDZ domain-containing protein.	Adhesion G protein-coupled receptor V1.	0.530
H3A9U0_LATCH	PDZD7	ENSLACP00000006411	ENSLACP00000000972	PDZ domain-containing protein.	PDZ domain containing 7.	0.892
H3AIG1_LATCH	ADGRV1	ENSLACP00000009432	ENSLACP00000010057	Uncharacterized protein.	Adhesion G protein-coupled receptor V1.	0.543