STRINGSTRING
DRD4 DRD4 CNTD1 CNTD1 LOC102351466 LOC102351466 H2ZS97_LATCH H2ZS97_LATCH APPL2 APPL2 ADIPOQ ADIPOQ ITGAV ITGAV SLC43A1 SLC43A1 H2ZVD1_LATCH H2ZVD1_LATCH PIM3 PIM3 WNK4 WNK4 LOC102354291 LOC102354291 DRD3 DRD3 H2ZYB6_LATCH H2ZYB6_LATCH PIP4P2 PIP4P2 RAB11FIP5 RAB11FIP5 NEDD4L NEDD4L H3A0M2_LATCH H3A0M2_LATCH VAMP8 VAMP8 CD200 CD200 OPRD1 OPRD1 LOC102352528 LOC102352528 KCNE4 KCNE4 ATF4 ATF4 RAB23 RAB23 SYT11 SYT11 VIP VIP SLC26A5 SLC26A5 PKD2 PKD2 KCNE3 KCNE3 SREBF2 SREBF2 HECW1 HECW1 WNK3 WNK3 PEA15 PEA15 IL1RAPL1 IL1RAPL1 NEU3 NEU3 SERPINE2 SERPINE2 H3A6V0_LATCH H3A6V0_LATCH H3A6Z2_LATCH H3A6Z2_LATCH SLC43A2 SLC43A2 LOC102345511 LOC102345511 FMR1 FMR1 PIM2 PIM2 CHP1 CHP1 H3ACA4_LATCH H3ACA4_LATCH NUP153 NUP153 ANKRD13A ANKRD13A FRMD4A FRMD4A SVIP SVIP LTA LTA CCN3 CCN3 GOPC GOPC ERLEC1 ERLEC1 INPP5K INPP5K H3AEV1_LATCH H3AEV1_LATCH LOC102361922 LOC102361922 WWP2 WWP2 SIRT6 SIRT6 LOC102347917 LOC102347917 ITGB1BP1 ITGB1BP1 CRY1 CRY1 ACVR1C ACVR1C CDK5 CDK5 H3AJC3_LATCH H3AJC3_LATCH REM1 REM1 MIDN MIDN RSAD2 RSAD2 ANKRD13D ANKRD13D LOC102346566 LOC102346566 HECW2 HECW2 HMGCR HMGCR PRRT2 PRRT2 STK39 STK39 H3AM01_LATCH H3AM01_LATCH LOC102356355 LOC102356355 ANKRD27 ANKRD27 PNKD PNKD UNC119 UNC119 VPS35 VPS35 PCSK9 PCSK9 TRH TRH UBE2J1 UBE2J1 DERL3 DERL3 UCN UCN LEP LEP SNX12 SNX12 FAM3D FAM3D H3AQD8_LATCH H3AQD8_LATCH LOC102365364 LOC102365364 YRDC YRDC VAMP3 VAMP3 CBARP CBARP LOC102362376 LOC102362376 BAG4 BAG4 APPL1 APPL1 BRAF BRAF BAG3 BAG3 OAZ2 OAZ2 NDFIP1 NDFIP1 RAP1B RAP1B TIFAB TIFAB CRHBP CRHBP LRRTM1 LRRTM1 SLC30A1 SLC30A1 SESTD1 SESTD1 LRRK2 LRRK2 RUBCN RUBCN NDUFAF2 NDUFAF2 H3AWN2_LATCH H3AWN2_LATCH PXK PXK RRAD RRAD CAV1 CAV1 ATXN2 ATXN2 SERGEF SERGEF NEU2 NEU2 H3AYA9_LATCH H3AYA9_LATCH LRRTM2 LRRTM2 MMP9 MMP9 SREBF1 SREBF1 C1QTNF9 C1QTNF9 ATG5 ATG5 LOC102363010 LOC102363010 SYT4 SYT4 RANGAP1 RANGAP1 KCNRG KCNRG PRR5 PRR5 RAB33B RAB33B RAB11FIP1 RAB11FIP1 ARL6IP5 ARL6IP5 GHRL GHRL KCNE2 KCNE2 STXBP3 STXBP3 UBE2G2 UBE2G2 KCNE1 KCNE1 CNN2 CNN2 KLF7 KLF7 STC1 STC1 ABCG8 ABCG8 RACK1 RACK1 NR1H2 NR1H2 RHBDF2 RHBDF2 LRSAM1 LRSAM1 ANKRD13B ANKRD13B TPR TPR NEDD4 NEDD4 CLIC2 CLIC2 INHBB INHBB SYTL4 SYTL4 SNX3 SNX3 PKDCC PKDCC ABCG5 ABCG5 CYFIP1 CYFIP1 CD74 CD74 ABCC8 ABCC8 WNK2 WNK2 ATG3 ATG3 KCNB1 KCNB1 KCNJ11 KCNJ11 ANO9 ANO9 DMTN DMTN REM2 REM2 CRYAA CRYAA LOC102346019 LOC102346019 OSTN OSTN NF1 NF1 IL1RAPL2 IL1RAPL2 PACSIN1 PACSIN1 RHBDF1 RHBDF1 PACSIN2 PACSIN2 RAB11FIP3 RAB11FIP3 NDFIP2 NDFIP2 LOC102354752 LOC102354752 COMMD1 COMMD1 FGF23 FGF23 CTTNBP2NL CTTNBP2NL THBS1 THBS1 DERL2 DERL2 OS9 OS9 H3BFU5_LATCH H3BFU5_LATCH WNK1 WNK1 PSMD9 PSMD9 SIRT4 SIRT4 CAV3 CAV3 DRD2 DRD2 H3BGE9_LATCH H3BGE9_LATCH CRY2 CRY2 RAP1A RAP1A CRYAB CRYAB ARHGAP1 ARHGAP1 RABGEF1 RABGEF1 YOD1 YOD1 NR1H3 NR1H3 PACSIN3 PACSIN3 LOC102351798 LOC102351798 LGALS3 LGALS3 RIN3 RIN3 WDR54 WDR54 LOC102362796 LOC102362796 BARD1 BARD1 PID1 PID1 APOD APOD EPO EPO ADTRP ADTRP TNFRSF1B TNFRSF1B LOC102346105 LOC102346105
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (382 aa)
CNTD1Cyclin N-terminal domain containing 1. (274 aa)
LOC102351466Uncharacterized protein. (201 aa)
H2ZS97_LATCHTNF_2 domain-containing protein. (143 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (484 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (259 aa)
ITGAVIntegrin_alpha2 domain-containing protein. (597 aa)
SLC43A1Solute carrier family 43 member 1. (556 aa)
H2ZVD1_LATCHUncharacterized protein. (104 aa)
PIM3Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (324 aa)
WNK4WNK lysine deficient protein kinase 4. (1163 aa)
LOC102354291Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (169 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (443 aa)
H2ZYB6_LATCHUncharacterized protein. (324 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
RAB11FIP5RAB11 family interacting protein 5. (389 aa)
NEDD4LE3 ubiquitin-protein ligase. (876 aa)
H3A0M2_LATCHUncharacterized protein. (676 aa)
VAMP8Vesicle associated membrane protein 8. (104 aa)
CD200Uncharacterized protein. (224 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (376 aa)
LOC102352528G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (167 aa)
ATF4Activating transcription factor 4. (374 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
SYT11Synaptotagmin 11. (429 aa)
VIPVasoactive intestinal peptide. (205 aa)
SLC26A5Solute carrier family 26 member 5. (755 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (890 aa)
KCNE3Uncharacterized protein. (92 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (1083 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1549 aa)
WNK3WNK lysine deficient protein kinase 3. (1769 aa)
PEA15Proliferation and apoptosis adaptor protein 15. (133 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (437 aa)
NEU3Neuraminidase 3. (339 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (403 aa)
H3A6V0_LATCHUncharacterized protein. (190 aa)
H3A6Z2_LATCHGMP_PDE_delta domain-containing protein. (185 aa)
SLC43A2Solute carrier family 43 member 2. (492 aa)
LOC102345511Uncharacterized protein. (292 aa)
FMR1Fragile X mental retardation 1. (627 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (324 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
H3ACA4_LATCHIg-like domain-containing protein. (156 aa)
NUP153Nucleoporin 153. (1449 aa)
ANKRD13AAnkyrin repeat domain 13A. (469 aa)
FRMD4AFERM domain containing 4A. (993 aa)
SVIPSi:ch73-147o17.1. (80 aa)
LTALymphotoxin alpha. (166 aa)
CCN3Cellular communication network factor 3. (345 aa)
GOPCGolgi-associated PDZ and coiled-coil motif containing. (456 aa)
ERLEC1Endoplasmic reticulum lectin 1. (486 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (476 aa)
H3AEV1_LATCHTNF_2 domain-containing protein. (230 aa)
LOC102361922Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family. (448 aa)
WWP2E3 ubiquitin-protein ligase. (883 aa)
SIRT6Sirtuin 6. (375 aa)
LOC102347917Uncharacterized protein. (301 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
CRY1Cryptochrome circadian regulator 1. (653 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
CDK5Cyclin dependent kinase 5. (290 aa)
H3AJC3_LATCHGalectin. (249 aa)
REM1RRAD and GEM like GTPase 1. (300 aa)
MIDNMidnolin. (524 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (360 aa)
ANKRD13DAnkyrin repeat domain 13D. (611 aa)
LOC102346566Annexin. (343 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1586 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (882 aa)
PRRT2Uncharacterized protein. (97 aa)
STK39Serine/threonine kinase 39. (493 aa)
H3AM01_LATCHIntegrin beta; Belongs to the integrin beta chain family. (769 aa)
LOC102356355TNFR-Cys domain-containing protein. (163 aa)
ANKRD27Ankyrin repeat domain 27. (888 aa)
PNKDPNKD metallo-beta-lactamase domain containing. (304 aa)
UNC119Unc-119 lipid binding chaperone. (257 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (790 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (672 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (262 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (321 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (203 aa)
UCNUrocortin. (167 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
SNX12Sorting nexin 12. (174 aa)
FAM3DFamily with sequence similarity 3 member D. (228 aa)
H3AQD8_LATCHUncharacterized protein. (565 aa)
LOC102365364Cryptochrome circadian regulator 3a. (616 aa)
YRDCYrdC N6-threonylcarbamoyltransferase domain containing. (277 aa)
VAMP3Vesicle associated membrane protein 3. (138 aa)
CBARPCACN subunit beta associated regulatory protein. (667 aa)
LOC102362376Protein kinase domain containing, cytoplasmic b. (381 aa)
BAG4BCL2 associated athanogene 4. (454 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (709 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (768 aa)
BAG3BCL2 associated athanogene 3. (561 aa)
OAZ2Uncharacterized protein. (187 aa)
NDFIP1Nedd4 family interacting protein 1. (212 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
TIFABTIFA inhibitor. (149 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (323 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (521 aa)
SLC30A1Solute carrier family 30 member 1. (518 aa)
SESTD1SEC14 and spectrin domain containing 1. (615 aa)
LRRK2Leucine rich repeat kinase 2. (2508 aa)
RUBCNRubicon autophagy regulator. (924 aa)
NDUFAF2NADH:ubiquinone oxidoreductase complex assembly factor 2. (167 aa)
H3AWN2_LATCHCryptochrome circadian regulator 4. (531 aa)
PXKPX domain containing serine/threonine kinase like. (577 aa)
RRADRRAD, Ras related glycolysis inhibitor and calcium channel regulator. (306 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
ATXN2Ataxin 2. (1085 aa)
SERGEFSecretion regulating guanine nucleotide exchange factor. (406 aa)
NEU2Neuraminidase 2. (381 aa)
H3AYA9_LATCHProtein kinase domain-containing protein. (357 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (522 aa)
MMP9Matrix metallopeptidase 9. (682 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1100 aa)
C1QTNF9C1q domain-containing protein. (198 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
LOC102363010Si:ch211-51c14.1. (475 aa)
SYT4Synaptotagmin 4. (434 aa)
RANGAP1Ran GTPase activating protein 1. (615 aa)
KCNRGPotassium channel regulator. (275 aa)
PRR5Uncharacterized protein. (599 aa)
RAB33BRAB33B, member RAS oncogene family. (230 aa)
RAB11FIP1RAB11 family interacting protein 1. (1225 aa)
ARL6IP5PRA1 family protein. (196 aa)
GHRLMotilin_assoc domain-containing protein. (110 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (125 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (597 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (168 aa)
KCNE1Uncharacterized protein. (122 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (302 aa)
KLF7Kruppel like factor 7. (294 aa)
STC1Stanniocalcin 1. (250 aa)
ABCG8ATP binding cassette subfamily G member 8. (677 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (426 aa)
RHBDF2Rhomboid 5 homolog 2. (869 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (732 aa)
ANKRD13BAnkyrin repeat domain 13B. (591 aa)
TPRTranslocated promoter region, nuclear basket protein. (2360 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1313 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (251 aa)
INHBBInhibin subunit beta B. (393 aa)
SYTL4Synaptotagmin like 4. (641 aa)
SNX3Sorting nexin 3. (108 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (503 aa)
ABCG5ATP binding cassette subfamily G member 5. (438 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1259 aa)
CD74CD74 molecule. (279 aa)
ABCC8ATP binding cassette subfamily C member 8. (1591 aa)
WNK2WNK lysine deficient protein kinase 2. (1994 aa)
ATG3Autophagy-related protein 3. (314 aa)
KCNB1Potassium voltage-gated channel, Shab-related subfamily, member 1; Belongs to the potassium channel family. (677 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (392 aa)
ANO9Anoctamin. (750 aa)
DMTNDematin actin binding protein. (406 aa)
REM2RRAD and GEM like GTPase 2. (295 aa)
CRYAACrystallin, alpha A; Belongs to the small heat shock protein (HSP20) family. (173 aa)
LOC102346019C1q domain-containing protein. (226 aa)
OSTNOsteocrin. (136 aa)
NF1Neurofibromin 1. (2814 aa)
IL1RAPL2Interleukin 1 receptor accessory protein-like 2. (429 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons 1. (490 aa)
RHBDF1Rhomboid 5 homolog 1. (805 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (330 aa)
RAB11FIP3RAB11 family interacting protein 3. (497 aa)
NDFIP2Nedd4 family interacting protein 2. (175 aa)
LOC102354752VPS9 domain-containing protein. (197 aa)
COMMD1Copper metabolism domain containing 1. (188 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (249 aa)
CTTNBP2NLCTTNBP2 N-terminal like. (644 aa)
THBS1Thrombospondin 1. (1170 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
OS9OS9 endoplasmic reticulum lectin. (662 aa)
H3BFU5_LATCHAIP3 domain-containing protein. (914 aa)
WNK1WNK lysine deficient protein kinase 1. (2654 aa)
PSMD9Proteasome 26S subunit, non-ATPase 9. (210 aa)
SIRT4NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (315 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
DRD2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
H3BGE9_LATCHUncharacterized protein. (273 aa)
CRY2Cryptochrome circadian regulator 2. (434 aa)
RAP1ARAP1A, member of RAS oncogene family b. (185 aa)
CRYABCrystallin alpha B; Belongs to the small heat shock protein (HSP20) family. (173 aa)
ARHGAP1Rho GTPase activating protein 1. (318 aa)
RABGEF1RAB guanine nucleotide exchange factor (GEF) 1. (532 aa)
YOD1YOD1 deubiquitinase. (304 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (375 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (486 aa)
LOC102351798Galectin. (167 aa)
LGALS3Galectin. (274 aa)
RIN3Ras and Rab interactor 3. (951 aa)
WDR54WD repeat domain 54. (193 aa)
LOC102362796Uncharacterized protein. (451 aa)
BARD1BRCA1 associated RING domain 1. (866 aa)
PID1Phosphotyrosine interaction domain containing 1. (217 aa)
APODApolipoprotein D; Belongs to the calycin superfamily. Lipocalin family. (189 aa)
EPOErythropoietin. (179 aa)
ADTRPUncharacterized protein. (229 aa)
TNFRSF1BTNF receptor superfamily member 1B. (465 aa)
LOC102346105ANK_REP_REGION domain-containing protein. (133 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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