(12 nodes) Chaperone-mediated protein complex assembly network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSMG1	Proteasome assembly chaperone 1. (287 aa)
	BBS12	Bardet-Biedl syndrome 12. (709 aa)
	BBS10	Bardet-Biedl syndrome 10. (714 aa)
	TMEM35A	Transmembrane protein 35A. (166 aa)
	NDUFAF1	NADH:ubiquinone oxidoreductase complex assembly factor 1. (309 aa)
	PSMG2	Proteasome assembly chaperone 2. (205 aa)
	CCT2	Chaperonin containing TCP1 subunit 2. (535 aa)
	MKKS	McKusick-Kaufman syndrome. (575 aa)
	LONP1	Lon protease homolog; Belongs to the peptidase S16 family. (975 aa)
	PFDN6	Prefoldin subunit 6. (126 aa)
	PSMG3	Proteasome assembly chaperone 3. (122 aa)
	HSPA4	Heat shock protein family A (Hsp70) member 4. (783 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS10	BBS12	ENSLACP00000001885	ENSLACP00000001386	Bardet-Biedl syndrome 10.	Bardet-Biedl syndrome 12.	0.875
BBS10	CCT2	ENSLACP00000001885	ENSLACP00000005828	Bardet-Biedl syndrome 10.	Chaperonin containing TCP1 subunit 2.	0.981
BBS10	HSPA4	ENSLACP00000001885	ENSLACP00000011701	Bardet-Biedl syndrome 10.	Heat shock protein family A (Hsp70) member 4.	0.473
BBS10	LONP1	ENSLACP00000001885	ENSLACP00000017122	Bardet-Biedl syndrome 10.	Lon protease homolog; Belongs to the peptidase S16 family.	0.527
BBS10	MKKS	ENSLACP00000001885	ENSLACP00000006659	Bardet-Biedl syndrome 10.	McKusick-Kaufman syndrome.	0.697
BBS10	PFDN6	ENSLACP00000001885	ENSLACP00000009379	Bardet-Biedl syndrome 10.	Prefoldin subunit 6.	0.590
BBS12	BBS10	ENSLACP00000001386	ENSLACP00000001885	Bardet-Biedl syndrome 12.	Bardet-Biedl syndrome 10.	0.875
BBS12	CCT2	ENSLACP00000001386	ENSLACP00000005828	Bardet-Biedl syndrome 12.	Chaperonin containing TCP1 subunit 2.	0.581
BBS12	MKKS	ENSLACP00000001386	ENSLACP00000006659	Bardet-Biedl syndrome 12.	McKusick-Kaufman syndrome.	0.811
CCT2	BBS10	ENSLACP00000005828	ENSLACP00000001885	Chaperonin containing TCP1 subunit 2.	Bardet-Biedl syndrome 10.	0.981
CCT2	BBS12	ENSLACP00000005828	ENSLACP00000001386	Chaperonin containing TCP1 subunit 2.	Bardet-Biedl syndrome 12.	0.581
CCT2	HSPA4	ENSLACP00000005828	ENSLACP00000011701	Chaperonin containing TCP1 subunit 2.	Heat shock protein family A (Hsp70) member 4.	0.619
CCT2	LONP1	ENSLACP00000005828	ENSLACP00000017122	Chaperonin containing TCP1 subunit 2.	Lon protease homolog; Belongs to the peptidase S16 family.	0.552
CCT2	MKKS	ENSLACP00000005828	ENSLACP00000006659	Chaperonin containing TCP1 subunit 2.	McKusick-Kaufman syndrome.	0.981
CCT2	PFDN6	ENSLACP00000005828	ENSLACP00000009379	Chaperonin containing TCP1 subunit 2.	Prefoldin subunit 6.	0.813
HSPA4	BBS10	ENSLACP00000011701	ENSLACP00000001885	Heat shock protein family A (Hsp70) member 4.	Bardet-Biedl syndrome 10.	0.473
HSPA4	CCT2	ENSLACP00000011701	ENSLACP00000005828	Heat shock protein family A (Hsp70) member 4.	Chaperonin containing TCP1 subunit 2.	0.619
HSPA4	MKKS	ENSLACP00000011701	ENSLACP00000006659	Heat shock protein family A (Hsp70) member 4.	McKusick-Kaufman syndrome.	0.473
LONP1	BBS10	ENSLACP00000017122	ENSLACP00000001885	Lon protease homolog; Belongs to the peptidase S16 family.	Bardet-Biedl syndrome 10.	0.527
LONP1	CCT2	ENSLACP00000017122	ENSLACP00000005828	Lon protease homolog; Belongs to the peptidase S16 family.	Chaperonin containing TCP1 subunit 2.	0.552