STRINGSTRING
LOC102357156 LOC102357156 NUDT6 NUDT6 HPGD-2 HPGD-2 QDPR QDPR IDH1 IDH1 GPD1L GPD1L PHGDH PHGDH CTBP1 CTBP1 HSD17B8 HSD17B8 EHHADH EHHADH PARP14 PARP14 CTBP2 CTBP2 LOC102356776 LOC102356776 GAPDH GAPDH HADHA HADHA GLYR1 GLYR1 ME2 ME2 H3AL20_LATCH H3AL20_LATCH ME3 ME3 SIRT7 SIRT7 H3AJ92_LATCH H3AJ92_LATCH SIRT1 SIRT1 LOC102362883 LOC102362883 H3AH67_LATCH H3AH67_LATCH SIRT6 SIRT6 HIBADH HIBADH IDH3G IDH3G SIRT5 SIRT5 IDH3B IDH3B HPGD HPGD AHCY AHCY LOC102348458 LOC102348458 IDH2 IDH2 SIRT4 SIRT4 NDUFV1 NDUFV1 GPD1 GPD1 UGDH UGDH UXS1 UXS1 SIRT3 SIRT3 IDH3A IDH3A GAPDHS GAPDHS GRHPR GRHPR HADH HADH PARP1 PARP1 NDUFS2 NDUFS2 LOC102354271 LOC102354271 H2ZRQ5_LATCH H2ZRQ5_LATCH RNLS RNLS BDH2 BDH2 CRYL1 CRYL1 H2ZUR6_LATCH H2ZUR6_LATCH LOC102351739 LOC102351739 SORD SORD LOC102358828 LOC102358828 ALDH1A3 ALDH1A3 H3BDU0_LATCH H3BDU0_LATCH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102357156Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
NUDT6Nudix hydrolase 6. (308 aa)
HPGD-2Uncharacterized protein. (86 aa)
QDPRQuinoid dihydropteridine reductase. (241 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
GPD1LGlycerol-3-phosphate dehydrogenase [NAD(+)]. (351 aa)
PHGDHPhosphoglycerate dehydrogenase. (522 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (255 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (537 aa)
PARP14Poly [ADP-ribose] polymerase. (1819 aa)
CTBP2C-terminal binding protein 2. (1002 aa)
LOC102356776Glycerol-3-phosphate dehydrogenase [NAD(+)]. (348 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (359 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (766 aa)
GLYR1Glyoxylate reductase 1 homolog. (541 aa)
ME2Malic enzyme. (543 aa)
H3AL20_LATCHPoly [ADP-ribose] polymerase. (197 aa)
ME3Malic enzyme. (617 aa)
SIRT7Sirtuin 7. (413 aa)
H3AJ92_LATCHPoly [ADP-ribose] polymerase. (308 aa)
SIRT1Sirtuin 1. (729 aa)
LOC102362883Iso_dh domain-containing protein. (384 aa)
H3AH67_LATCHGlyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (368 aa)
SIRT6Sirtuin 6. (375 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase. (251 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (400 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (310 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (363 aa)
HPGD15-hydroxyprostaglandin dehydrogenase. (165 aa)
AHCYAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (507 aa)
LOC102348458Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (402 aa)
SIRT4NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (315 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (475 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (350 aa)
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (424 aa)
UXS1UDP-glucuronate decarboxylase 1. (359 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (396 aa)
GRHPRGlyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
HADHHydroxyacyl-CoA dehydrogenase. (309 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (466 aa)
LOC102354271UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (495 aa)
H2ZRQ5_LATCH2-Hacid_dh_C domain-containing protein. (80 aa)
RNLSRenalase, FAD dependent amine oxidase. (254 aa)
BDH23-hydroxybutyrate dehydrogenase 2. (249 aa)
CRYL1Crystallin lambda 1. (319 aa)
H2ZUR6_LATCHPoly [ADP-ribose] polymerase. (601 aa)
LOC1023517392-Hacid_dh_C domain-containing protein. (197 aa)
SORDSorbitol dehydrogenase. (356 aa)
LOC102358828Zgc:136493; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (350 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (507 aa)
H3BDU0_LATCHNAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (318 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.