STRINGSTRING
TRH TRH CLTRN CLTRN SYT4 SYT4 DTNBP1 DTNBP1 PSEN1 PSEN1 RAB3GAP1 RAB3GAP1 SLC6A1 SLC6A1 SLC17A8 SLC17A8 SLC7A5 SLC7A5 ACE2 ACE2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (262 aa)
CLTRNCollectrin domain-containing protein. (226 aa)
SYT4Synaptotagmin 4. (434 aa)
DTNBP1Dystrobrevin binding protein 1. (355 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (1006 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (601 aa)
SLC17A8Solute carrier family 17 member 8. (439 aa)
SLC7A5Solute carrier family 7 member 5. (522 aa)
ACE2Angiotensin-converting enzyme. (814 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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