(21 nodes) Cardiac muscle cell development network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CSRP3	Cysteine and glycine rich protein 3. (192 aa)
	ADRA1A	Adrenoceptor alpha 1A. (459 aa)
	NRAP	Nebulin related anchoring protein. (1783 aa)
	ASB2	Ankyrin repeat and SOCS box containing 2. (658 aa)
	CXADR	CXADR Ig-like cell adhesion molecule. (297 aa)
	LRRC10	Uncharacterized protein. (244 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (453 aa)
	LOC102347576	SH3 domain-containing protein. (2968 aa)
	LRRC10B	Leucine rich repeat containing 10B. (278 aa)
	PDLIM5	PDZ and LIM domain 5. (629 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (1039 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	SRF	Serum response factor. (520 aa)
	AKAP13	PH domain-containing protein. (644 aa)
	NKX2-5	NK2 homeobox 5. (296 aa)
	LOC102365660	Uncharacterized protein. (187 aa)
	LOC102366172	Uncharacterized protein. (183 aa)
	H3B8U3_LATCH	Serine/threonine-protein kinase TOR. (1418 aa)
	H3B976_LATCH	Uncharacterized protein. (1585 aa)
	MTOR	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
	MAP2K4	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (463 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG5	H3B8U3_LATCH	ENSLACP00000015035	ENSLACP00000018314	Autophagy protein 5; Involved in autophagic vesicle formation.	Serine/threonine-protein kinase TOR.	0.453
ATG5	MTOR	ENSLACP00000015035	ENSLACP00000018843	Autophagy protein 5; Involved in autophagic vesicle formation.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.453
CSRP3	LOC102347576	ENSLACP00000018230	ENSLACP00000007847	Cysteine and glycine rich protein 3.	SH3 domain-containing protein.	0.442
CSRP3	LOC102365660	ENSLACP00000018230	ENSLACP00000017843	Cysteine and glycine rich protein 3.	Uncharacterized protein.	0.546
CSRP3	LOC102366172	ENSLACP00000018230	ENSLACP00000017946	Cysteine and glycine rich protein 3.	Uncharacterized protein.	0.546
CSRP3	NRAP	ENSLACP00000018230	ENSLACP00000002953	Cysteine and glycine rich protein 3.	Nebulin related anchoring protein.	0.576
H3B8U3_LATCH	ATG5	ENSLACP00000018314	ENSLACP00000015035	Serine/threonine-protein kinase TOR.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.453
H3B8U3_LATCH	MTOR	ENSLACP00000018314	ENSLACP00000018843	Serine/threonine-protein kinase TOR.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.944
LOC102347576	CSRP3	ENSLACP00000007847	ENSLACP00000018230	SH3 domain-containing protein.	Cysteine and glycine rich protein 3.	0.442
LOC102347576	LOC102365660	ENSLACP00000007847	ENSLACP00000017843	SH3 domain-containing protein.	Uncharacterized protein.	0.475
LOC102347576	LOC102366172	ENSLACP00000007847	ENSLACP00000017946	SH3 domain-containing protein.	Uncharacterized protein.	0.475
LOC102347576	NRAP	ENSLACP00000007847	ENSLACP00000002953	SH3 domain-containing protein.	Nebulin related anchoring protein.	0.433
LOC102365660	CSRP3	ENSLACP00000017843	ENSLACP00000018230	Uncharacterized protein.	Cysteine and glycine rich protein 3.	0.546
LOC102365660	LOC102347576	ENSLACP00000017843	ENSLACP00000007847	Uncharacterized protein.	SH3 domain-containing protein.	0.475
LOC102365660	NRAP	ENSLACP00000017843	ENSLACP00000002953	Uncharacterized protein.	Nebulin related anchoring protein.	0.431
LOC102366172	CSRP3	ENSLACP00000017946	ENSLACP00000018230	Uncharacterized protein.	Cysteine and glycine rich protein 3.	0.546
LOC102366172	LOC102347576	ENSLACP00000017946	ENSLACP00000007847	Uncharacterized protein.	SH3 domain-containing protein.	0.475
LOC102366172	NRAP	ENSLACP00000017946	ENSLACP00000002953	Uncharacterized protein.	Nebulin related anchoring protein.	0.431
MTOR	ATG5	ENSLACP00000018843	ENSLACP00000015035	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.453
MTOR	H3B8U3_LATCH	ENSLACP00000018843	ENSLACP00000018314	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase TOR.	0.944