STRINGSTRING
TGFB1 TGFB1 H2ZRN8_LATCH H2ZRN8_LATCH WWTR1 WWTR1 ITGB6 ITGB6 CCN2 CCN2 H2ZT48_LATCH H2ZT48_LATCH CRACD CRACD IMMT IMMT CLRN1 CLRN1 HAAO HAAO BBS12 BBS12 APP APP KLHL10 KLHL10 ACP5 ACP5 NKIRAS1 NKIRAS1 BBS10 BBS10 LOC102354291 LOC102354291 BBS4 BBS4 TRIM32 TRIM32 CLN8 CLN8 CALB2 CALB2 SMO SMO EPAS1 EPAS1 LSR LSR TRAF6 TRAF6 YAP1 YAP1 PRKAA1 PRKAA1 SCGN SCGN WWTR1-2 WWTR1-2 H3A478_LATCH H3A478_LATCH H3A4S8_LATCH H3A4S8_LATCH WNK3 WNK3 CXADR CXADR RB1 RB1 CCDC66 CCDC66 H3A6Z7_LATCH H3A6Z7_LATCH ANKRD12 ANKRD12 PRDM14 PRDM14 LOC102359111 LOC102359111 BSG BSG LOC102353242 LOC102353242 LAMP2 LAMP2 CTSH CTSH MKKS MKKS HEXB HEXB SPATA7 SPATA7 CRB1 CRB1 RP1L1 RP1L1 ILDR2 ILDR2 BAX BAX ATP2B3 ATP2B3 TPP1 TPP1 H3AF25_LATCH H3AF25_LATCH DCTN1 DCTN1 FH FH FKBP14 FKBP14 FGGY FGGY TNFSF11 TNFSF11 STRAP STRAP IQCB1 IQCB1 H3AIG1_LATCH H3AIG1_LATCH LOC102366915 LOC102366915 ADGRV1 ADGRV1 GATA1 GATA1 VSTM4 VSTM4 KDR KDR MTF1 MTF1 ANKRD11 ANKRD11 CA7 CA7 NOX4 NOX4 USH1G USH1G USP45 USP45 H3ARD8_LATCH H3ARD8_LATCH INAVA INAVA LRRC45 LRRC45 LOC102350991 LOC102350991 PSEN1 PSEN1 BAG3 BAG3 TMEM175 TMEM175 STK11 STK11 TJP2 TJP2 ZNF830 ZNF830 ERCC6 ERCC6 CAV1 CAV1 NXNL2 NXNL2 VSIG1 VSIG1 MFSD2A MFSD2A HOMER1 HOMER1 RHO RHO PBLD PBLD SASH3 SASH3 TJP3 TJP3 CDHR1 CDHR1 MTM1 MTM1 SRF SRF RP1 RP1 SNX10 SNX10 BBS2 BBS2 MSTN MSTN CTNNB1 CTNNB1 NANOS1 NANOS1 FXN FXN CLDN5 CLDN5 CROCC CROCC NCDN NCDN USH1C USH1C CSRP3 CSRP3 VPS54 VPS54 ABCC8 ABCC8 LOC102347432 LOC102347432 FGF2 FGF2 NXNL1 NXNL1 HOXA13 HOXA13 LOC102354477 LOC102354477 HOMER2 HOMER2 LRRK1 LRRK1 CAV3 CAV3 P2RX1 P2RX1 TLR9 TLR9 TJP1 TJP1 LOC102358538 LOC102358538 CD34 CD34 MKS1 MKS1 CRB2 CRB2 LOC102359098 LOC102359098 NPHP4 NPHP4 MBP MBP LOC102356247 LOC102356247 DRAM2 DRAM2 TP53INP2 TP53INP2 LCA5 LCA5 M3XLI6_LATCH M3XLI6_LATCH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
H2ZRN8_LATCHUncharacterized protein. (160 aa)
WWTR1WW domain containing transcription regulator 1. (264 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (675 aa)
CCN2Cellular communication network factor 2. (344 aa)
H2ZT48_LATCHUncharacterized protein. (254 aa)
CRACDKIAA1211. (986 aa)
IMMTMICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (411 aa)
CLRN1Clarin 1. (232 aa)
HAAOUncharacterized protein. (252 aa)
BBS12Bardet-Biedl syndrome 12. (709 aa)
APPAmyloid beta precursor protein. (652 aa)
KLHL10Kelch like family member 10. (606 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (329 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (191 aa)
BBS10Bardet-Biedl syndrome 10. (714 aa)
LOC102354291Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (169 aa)
BBS4Bardet-Biedl syndrome 4. (537 aa)
TRIM32Tripartite motif containing 32. (647 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (294 aa)
CALB2Calbindin 2. (252 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (820 aa)
EPAS1Endothelial PAS domain protein 1. (861 aa)
LSRLipolysis stimulated lipoprotein receptor. (581 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
YAP1Yes associated protein 1. (324 aa)
PRKAA1Non-specific serine/threonine protein kinase. (552 aa)
SCGNSecretagogin, EF-hand calcium binding protein. (272 aa)
WWTR1-2WW domain-containing protein. (159 aa)
H3A478_LATCHPDZ domain-containing protein. (297 aa)
H3A4S8_LATCHUncharacterized protein. (2030 aa)
WNK3WNK lysine deficient protein kinase 3. (1769 aa)
CXADRCXADR Ig-like cell adhesion molecule. (297 aa)
RB1Uncharacterized protein. (411 aa)
CCDC66Coiled-coil domain containing 66. (966 aa)
H3A6Z7_LATCHBardet-Biedl syndrome 1. (596 aa)
ANKRD12Ankyrin repeat domain 12. (2105 aa)
PRDM14PR/SET domain 14. (599 aa)
LOC102359111Nanos homolog 1; Belongs to the nanos family. (224 aa)
BSGBasigin (Ok blood group). (368 aa)
LOC102353242Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1171 aa)
LAMP2Lysosomal associated membrane protein 2. (416 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (329 aa)
MKKSMcKusick-Kaufman syndrome. (575 aa)
HEXBBeta-hexosaminidase. (552 aa)
SPATA7Spermatogenesis associated 7. (398 aa)
CRB1Crumbs cell polarity complex component 1. (1366 aa)
RP1L1Uncharacterized protein. (1547 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (624 aa)
BAXUncharacterized protein. (223 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1259 aa)
TPP1Tripeptidyl peptidase 1. (569 aa)
H3AF25_LATCHUncharacterized protein. (117 aa)
DCTN1Dynactin 1a. (1139 aa)
FHFumarate hydratase. (491 aa)
FKBP14Peptidylprolyl isomerase. (211 aa)
FGGYFGGY carbohydrate kinase domain containing. (572 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (169 aa)
STRAPSerine/threonine kinase receptor associated protein. (329 aa)
IQCB1IQ motif containing B1. (601 aa)
H3AIG1_LATCHUncharacterized protein. (317 aa)
LOC102366915Uncharacterized protein. (146 aa)
ADGRV1Adhesion G protein-coupled receptor V1. (5847 aa)
GATA1GATA binding protein 1b. (432 aa)
VSTM4V-set and transmembrane domain containing 4. (328 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa)
MTF1Metal regulatory transcription factor 1. (669 aa)
ANKRD11Ankyrin repeat domain 11. (2717 aa)
CA7Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. (264 aa)
NOX4NADPH oxidase 4. (541 aa)
USH1GUSH1 protein network component sans. (471 aa)
USP45Ubiquitinyl hydrolase 1. (823 aa)
H3ARD8_LATCHUncharacterized protein. (2003 aa)
INAVAInnate immunity activator. (599 aa)
LRRC45Leucine rich repeat containing 45. (679 aa)
LOC102350991Uncharacterized protein. (1471 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
BAG3BCL2 associated athanogene 3. (561 aa)
TMEM175Transmembrane protein 175. (511 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
TJP2Tight junction protein 2a (zona occludens 2). (1241 aa)
ZNF830zf-C2H2_jaz domain-containing protein. (240 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1387 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
NXNL2Nucleoredoxin like 2. (157 aa)
VSIG1V-set and immunoglobulin domain containing 1. (339 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (549 aa)
HOMER1Homer scaffold protein 1. (367 aa)
RHORhodopsin. (355 aa)
PBLDPhenazine biosynthesis like protein domain containing. (288 aa)
SASH3SAM and SH3 domain containing 3. (433 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (859 aa)
CDHR1Cadherin related family member 1. (688 aa)
MTM1Myotubularin 1. (600 aa)
SRFSerum response factor. (520 aa)
RP1RP1 axonemal microtubule associated. (1901 aa)
SNX10Sorting nexin 10. (203 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (724 aa)
MSTNMyostatin. (372 aa)
CTNNB1Catenin beta 1. (781 aa)
NANOS1Nanos C2HC-type zinc finger 1; Belongs to the nanos family. (213 aa)
FXNFrataxin. (194 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (213 aa)
CROCCUncharacterized protein. (1191 aa)
NCDNNeurochondrin. (683 aa)
USH1CUSH1 protein network component harmonin. (830 aa)
CSRP3Cysteine and glycine rich protein 3. (192 aa)
VPS54VPS54 subunit of GARP complex. (980 aa)
ABCC8ATP binding cassette subfamily C member 8. (1591 aa)
LOC102347432Rhodopsin. (355 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
NXNL1Nucleoredoxin like 1. (221 aa)
HOXA13Homeobox A13b. (295 aa)
LOC102354477Uncharacterized protein. (838 aa)
HOMER2Homer scaffold protein 2. (354 aa)
LRRK1Leucine rich repeat kinase 1. (1987 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (403 aa)
TLR9Toll-like receptor 9. (1039 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1782 aa)
LOC102358538Growth differentiation factor 11. (381 aa)
CD34Uncharacterized protein. (378 aa)
MKS1MKS transition zone complex subunit 1. (561 aa)
CRB2Uncharacterized protein. (1473 aa)
LOC102359098Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1180 aa)
NPHP4Nephrocystin 4. (1207 aa)
MBPMyelin basic protein. (133 aa)
LOC102356247Uncharacterized protein. (636 aa)
DRAM2DNA damage regulated autophagy modulator 2. (142 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (232 aa)
LCA5Lebercilin LCA5. (743 aa)
M3XLI6_LATCHUncharacterized protein. (426 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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