STRINGSTRING
GFAP GFAP MECP2 MECP2 UFL1 UFL1 IL6 IL6 SKI SKI LYN LYN RB1 RB1 H2ZS97_LATCH H2ZS97_LATCH H3AEV1_LATCH H3AEV1_LATCH TP53 TP53 LOC102360711 LOC102360711 SLC7A5 SLC7A5 ABCC8 ABCC8 NF1 NF1 RNF10 RNF10 LOC102355265 LOC102355265 VEGFC VEGFC NF2 NF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (449 aa)
MECP2Methyl-CpG binding protein 2. (459 aa)
UFL1UFM1 specific ligase 1. (792 aa)
IL6Uncharacterized protein. (149 aa)
SKISKI proto-oncogene. (702 aa)
LYNTyrosine-protein kinase. (515 aa)
RB1Uncharacterized protein. (411 aa)
H2ZS97_LATCHTNF_2 domain-containing protein. (143 aa)
H3AEV1_LATCHTNF_2 domain-containing protein. (230 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
LOC102360711PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (299 aa)
SLC7A5Solute carrier family 7 member 5. (522 aa)
ABCC8ATP binding cassette subfamily C member 8. (1591 aa)
NF1Neurofibromin 1. (2814 aa)
RNF10Ring finger protein 10. (794 aa)
LOC102355265Neurofibromin 2b (merlin). (577 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (410 aa)
NF2Neurofibromin 2. (595 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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