(13 nodes) Positive regulation of SMAD protein signal transduction network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	DAB2	DAB adaptor protein 2. (745 aa)
	NUP93	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (722 aa)
	LOC102358988	Mothers against decapentaplegic homolog. (614 aa)
	BMP6	Bone morphogenetic protein 6. (428 aa)
	TGFBR1	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
	SMAD4	MH2 domain-containing protein. (412 aa)
	LOC102351081	Bone morphogenetic protein 16. (396 aa)
	BMP4	Bone morphogenetic protein 4. (460 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
	H3BEX6_LATCH	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
	H3BE69_LATCH	PID domain-containing protein. (136 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
	BMP2	Bone morphogenetic protein 2. (402 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	BMP4	ENSLACP00000016168	ENSLACP00000021723	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.903
BMP2	BMP6	ENSLACP00000016168	ENSLACP00000012388	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.666
BMP2	BMPR2	ENSLACP00000016168	ENSLACP00000017144	Bone morphogenetic protein 2.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.973
BMP2	H3BEX6_LATCH	ENSLACP00000016168	ENSLACP00000020447	Bone morphogenetic protein 2.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.749
BMP2	LOC102358988	ENSLACP00000016168	ENSLACP00000022115	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.711
BMP2	SMAD4	ENSLACP00000016168	ENSLACP00000009312	Bone morphogenetic protein 2.	MH2 domain-containing protein.	0.711
BMP2	TGFBR1	ENSLACP00000016168	ENSLACP00000008197	Bone morphogenetic protein 2.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.667
BMP4	BMP2	ENSLACP00000021723	ENSLACP00000016168	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.903
BMP4	BMP6	ENSLACP00000021723	ENSLACP00000012388	Bone morphogenetic protein 4.	Bone morphogenetic protein 6.	0.671
BMP4	BMPR2	ENSLACP00000021723	ENSLACP00000017144	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.973
BMP4	H3BEX6_LATCH	ENSLACP00000021723	ENSLACP00000020447	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.749
BMP4	LOC102358988	ENSLACP00000021723	ENSLACP00000022115	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.711
BMP4	SMAD4	ENSLACP00000021723	ENSLACP00000009312	Bone morphogenetic protein 4.	MH2 domain-containing protein.	0.815
BMP4	TGFBR1	ENSLACP00000021723	ENSLACP00000008197	Bone morphogenetic protein 4.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.667
BMP6	BMP2	ENSLACP00000012388	ENSLACP00000016168	Bone morphogenetic protein 6.	Bone morphogenetic protein 2.	0.666
BMP6	BMP4	ENSLACP00000012388	ENSLACP00000021723	Bone morphogenetic protein 6.	Bone morphogenetic protein 4.	0.671
BMP6	BMPR2	ENSLACP00000012388	ENSLACP00000017144	Bone morphogenetic protein 6.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.970
BMP6	H3BEX6_LATCH	ENSLACP00000012388	ENSLACP00000020447	Bone morphogenetic protein 6.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.637
BMP6	LOC102351081	ENSLACP00000012388	ENSLACP00000009064	Bone morphogenetic protein 6.	Bone morphogenetic protein 16.	0.670
BMP6	SMAD4	ENSLACP00000012388	ENSLACP00000009312	Bone morphogenetic protein 6.	MH2 domain-containing protein.	0.582