STRINGSTRING
DDR2 DDR2 PELI1 PELI1 BIRC2 BIRC2 RNF31 RNF31 CASP10 CASP10 H3A2R2_LATCH H3A2R2_LATCH H3A526_LATCH H3A526_LATCH RBCK1 RBCK1 LOC102348760 LOC102348760 BOK BOK FADD FADD UCN UCN RIPK1 RIPK1 SHARPIN SHARPIN ADPRHL2 ADPRHL2 CAV3 CAV3 MUTYH MUTYH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDR2Discoidin domain receptor tyrosine kinase 2. (838 aa)
PELI1Pellino E3 ubiquitin protein ligase 1. (445 aa)
BIRC2Baculoviral IAP repeat containing 2. (616 aa)
RNF31Uncharacterized protein. (1087 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (539 aa)
H3A2R2_LATCHUncharacterized protein; Belongs to the peptidase C14A family. (480 aa)
H3A526_LATCHUncharacterized protein; Belongs to the peptidase C14A family. (486 aa)
RBCK1IBR domain-containing protein. (175 aa)
LOC102348760Uncharacterized protein. (782 aa)
BOKBCL2 family apoptosis regulator BOK. (111 aa)
FADDFas associated via death domain. (193 aa)
UCNUrocortin. (167 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (667 aa)
SHARPINUncharacterized protein. (681 aa)
ADPRHL2ADP-ribose glycohydrolase ARH3; ADP-ribose glycohydrolase that preferentially hydrolyzes the scissile alpha-O-linkage attached to the anomeric C1'' position of ADP- ribose and acts on different substrates, such as proteins ADP- ribosylated on serine, free poly(ADP-ribose) and O-acetyl-ADP-D-ribose. Specifically acts as a serine mono-ADP- ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to serine residues on proteins, thereby playing a key role in DNA damage response. Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in [...] (370 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
MUTYHUncharacterized protein. (140 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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