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| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | IRX1 | Iroquois homeobox 1. (460 aa) |
| | LOC102345533 | T-box transcription factor 16. (438 aa) |
| | ALCAM | Activated leukocyte cell adhesion molecule. (530 aa) |
| | APAF1 | Apoptotic peptidase activating factor 1. (1202 aa) |
| | COMMD5 | COMM domain containing 5. (223 aa) |
| | H3AXS1_LATCH | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (313 aa) |
| | PRKACB | Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa) |
| | TCTN1 | Tectonic family member 1. (656 aa) |
| | M3XL62_LATCH | Uncharacterized protein. (269 aa) |
| | LUZP1 | Leucine zipper protein 1. (1044 aa) |
| | VDR | Vitamin D receptor. (427 aa) |
| | ENG | Endoglin. (674 aa) |
| | FUZ | Fuzzy planar cell polarity protein. (426 aa) |
| | MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (707 aa) |
| | MMP14 | Matrix metallopeptidase 14. (597 aa) |
| | LOC102356233 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (574 aa) |
| | LOC102356247 | Uncharacterized protein. (636 aa) |
| | LOC102358988 | Mothers against decapentaplegic homolog. (614 aa) |
| | H3BIS0_LATCH | Uncharacterized protein. (153 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (497 aa) |
| | BMP4 | Bone morphogenetic protein 4. (460 aa) |
| | TIMELESS | Timeless circadian regulator. (1272 aa) |
| | LOC102350297 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa) |
| | IFT52 | Intraflagellar transport 52. (440 aa) |
| | MKS1 | MKS transition zone complex subunit 1. (561 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (552 aa) |
| | HAND1 | Heart and neural crest derivatives expressed 1. (196 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1598 aa) |
| | ST14 | Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. (845 aa) |
| | H3BFZ2_LATCH | BHLH domain-containing protein. (165 aa) |
| | H3BFW7_LATCH | BHLH domain-containing protein. (161 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa) |
| | HNF1A | HNF1 homeobox A. (624 aa) |
| | CCDC40 | Coiled-coil domain containing 40. (859 aa) |
| | ESRP2 | Epithelial splicing regulatory protein 2. (721 aa) |
| | BMP7 | Bone morphogenetic protein 7. (425 aa) |
| | PHACTR4 | Phosphatase and actin regulator. (702 aa) |
| | HOXA5 | Homeobox A5. (269 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa) |
| | TMED2 | Transmembrane p24 trafficking protein 2. (208 aa) |
| | GNA13 | G protein subunit alpha 13. (377 aa) |
| | SOX8 | SRY-box transcription factor 8. (477 aa) |
| | EDN1 | Endothelin 1. (216 aa) |
| | MTHFD1 | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (930 aa) |
| | KIF26B | Kinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1974 aa) |
| | WT1 | WT1 transcription factor. (422 aa) |
| | SEMA3E | Semaphorin 3E; Belongs to the semaphorin family. (739 aa) |
| | LOC102366172 | Uncharacterized protein. (183 aa) |
| | LOC102365660 | Uncharacterized protein. (187 aa) |
| | ABL1 | Tyrosine-protein kinase. (1156 aa) |
| | H3B780_LATCH | Uncharacterized protein. (370 aa) |
| | SPRY1 | Sprouty RTK signaling antagonist 1. (320 aa) |
| | TBX2 | T-box transcription factor 2. (689 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | AR | Androgen receptor. (412 aa) |
| | NKX2-5 | NK2 homeobox 5. (296 aa) |
| | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (2690 aa) |
| | CTSZ | Cathepsin Z; Belongs to the peptidase C1 family. (295 aa) |
| | POPDC2 | Popeye domain containing 2. (366 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (401 aa) |
| | CLIC4 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (252 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (716 aa) |
| | SRF | Serum response factor. (520 aa) |
| | HHIP | Hedgehog interacting protein. (687 aa) |
| | LOC102356000 | Uncharacterized protein. (211 aa) |
| | LGR5 | Leucine rich repeat containing G protein-coupled receptor 5. (625 aa) |
| | TSC2 | TSC complex subunit 2. (1836 aa) |
| | LRRC1 | Uncharacterized protein. (155 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (148 aa) |
| | CCM2 | CCM2 scaffold protein. (447 aa) |
| | LOC102346204 | Protein kinase domain-containing protein. (227 aa) |
| | DDR1 | Discoidin domain receptor tyrosine kinase 1. (964 aa) |
| | BBS4 | Bardet-Biedl syndrome 4. (537 aa) |
| | DNAAF1 | Dynein assembly factor 1, axonemal. (263 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (820 aa) |
| | STK4 | Serine/threonine kinase 4. (488 aa) |
| | H3A0S5_LATCH | Uncharacterized protein. (547 aa) |
| | GATA3 | GATA binding protein 3. (447 aa) |
| | H3A1J6_LATCH | Uncharacterized protein. (646 aa) |
| | ASB2 | Ankyrin repeat and SOCS box containing 2. (658 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa) |
| | LOC102354865 | Uncharacterized protein. (746 aa) |
| | MTSS1 | MTSS I-BAR domain containing 1. (636 aa) |
| | OPA1 | OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (994 aa) |
| | LMO4 | LIM domain only 4b. (165 aa) |
| | PTCH1 | Patched 1. (1287 aa) |
| | GLI3 | GLI family zinc finger 3. (1456 aa) |
| | PKD1 | Polycystin 1, transient receptor potential channel interacting. (4241 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (348 aa) |
| | SHANK3 | SH3 and multiple ankyrin repeat domains 3. (1187 aa) |
| | LOC102355487 | Notochord homeobox. (242 aa) |
| | HAND2 | Heart and neural crest derivatives expressed 2. (210 aa) |
| | RET | Ret proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1090 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (890 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (112 aa) |
| | LOC102356523 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa) |
| | TBX6 | Uncharacterized protein. (101 aa) |
| | DLG5 | Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1821 aa) |
| | GSE1 | Gse1 coiled-coil protein. (1212 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (397 aa) |
| | TCF21 | Transcription factor 21. (179 aa) |
| | BSG | Basigin (Ok blood group). (368 aa) |
| | H3A8H2_LATCH | Uncharacterized protein. (541 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa) |
| | GBX2 | Gastrulation brain homeobox 2. (344 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa) |
| | CTSH | Cathepsin H; Belongs to the peptidase C1 family. (329 aa) |
| | ABL2 | Tyrosine-protein kinase. (1175 aa) |
| | GDF7 | Growth differentiation factor 7. (416 aa) |
| | PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1. (1450 aa) |
| | LOC102355595 | Si:dkey-91i10.2. (1049 aa) |
| | MTHFD1L | Uncharacterized protein. (90 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | ILK | Integrin linked kinase. (417 aa) |
| | KDM6A | Lysine (K)-specific demethylase 6A. (1452 aa) |
| | GREM1 | Gremlin 1, DAN family BMP antagonist. (189 aa) |
| | GDNF | Glial cell derived neurotrophic factor. (222 aa) |
| | TBX3 | T-box transcription factor 3. (713 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (387 aa) |
| | CTNNBIP1 | Catenin beta interacting protein 1. (81 aa) |
| | HS2ST1 | Heparan sulfate 2-O-sulfotransferase 1b. (347 aa) |
| | H3AC70_LATCH | LRRNT domain-containing protein. (132 aa) |
| | SEC24B | SEC24 homolog B, COPII coat complex component. (1197 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1143 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (294 aa) |
| | TMEM59L | Transmembrane protein 59 like. (340 aa) |
| | LOC102362951 | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa) |
| | CECR2 | CECR2 histone acetyl-lysine reader. (1363 aa) |
| | SETD2 | SET domain containing 2, histone lysine methyltransferase. (2541 aa) |
| | ARL13B | ADP ribosylation factor like GTPase 13B. (343 aa) |
| | MIB1 | Mindbomb E3 ubiquitin protein ligase 1. (989 aa) |
| | H3AFZ1_LATCH | Peptidase S72 domain-containing protein. (633 aa) |
| | CLUAP1 | Clusterin associated protein 1. (348 aa) |
| | DLL3 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (699 aa) |
| | AREG | Amphiregulin. (235 aa) |
| | LOC102353169 | Uncharacterized protein. (245 aa) |
| | FKBP14 | Peptidylprolyl isomerase. (211 aa) |
| | HECTD1 | HECT domain E3 ubiquitin protein ligase 1. (2580 aa) |
| | PRKX | Protein kinase X-linked; Belongs to the protein kinase superfamily. (285 aa) |
| | LOC102351081 | Bone morphogenetic protein 16. (396 aa) |
| | H3AHH6_LATCH | RHD domain-containing protein. (288 aa) |
| | SMAD4 | MH2 domain-containing protein. (412 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa) |
| | SHROOM3 | Shroom family member 3. (1790 aa) |
| | S1PR2 | Sphingosine-1-phosphate receptor 2. (352 aa) |
| | H3AJF8_LATCH | Peptidase S1 domain-containing protein. (483 aa) |
| | MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (650 aa) |
| | NOTO | Homeobox domain-containing protein. (234 aa) |
| | SUFU | SUFU negative regulator of hedgehog signaling. (422 aa) |
| | H3ALU1_LATCH | Uncharacterized protein. (1358 aa) |
| | H3AM65_LATCH | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (472 aa) |
| | SETDB2 | SET domain bifurcated histone lysine methyltransferase 2. (751 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa) |
| | ACVR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa) |
| | H3APB2_LATCH | Fork-head domain-containing protein. (408 aa) |
| | ARHGAP35 | Rho GTPase activating protein 35b. (1487 aa) |
| | STIL | STIL centriolar assembly protein. (1298 aa) |
| | TBX20 | T-box transcription factor 20. (441 aa) |
| | EFNB2 | Ephrin B2; Belongs to the ephrin family. (338 aa) |
| | SLIT2 | Slit guidance ligand 2. (1372 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (213 aa) |
| | HESX1 | HESX homeobox 1. (185 aa) |
| | GREB1L | GREB1 like retinoic acid receptor coactivator. (1842 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (604 aa) |
| | TSC1 | TSC complex subunit 1. (1217 aa) |
| | MICAL2 | Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1131 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1401 aa) |
| | EPHA2 | Uncharacterized protein. (979 aa) |
| | VASP | Vasodilator stimulated phosphoprotein. (444 aa) |
| | IRX3 | Iroquois homeobox 3. (447 aa) |
| | IFT57 | Intraflagellar transport 57. (428 aa) |
| | LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (955 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (688 aa) |
| | PLXND1 | Plexin D1. (1875 aa) |
| | KDM5B | Lysine demethylase 5B. (1659 aa) |
| | GREB1 | Uncharacterized protein. (1948 aa) |
| | DAG1 | Dystroglycan 1. (900 aa) |
| | BMP2 | Bone morphogenetic protein 2. (402 aa) |
| | DEAF1 | DEAF1 transcription factor. (565 aa) |
| | GLMN | Glomulin, FKBP associated protein. (597 aa) |
| | H3B277_LATCH | Uncharacterized protein. (4290 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (151 aa) |
| | SALL4 | Spalt like transcription factor 4. (1002 aa) |
| | PTK7 | Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1067 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1385 aa) |
| | CCDC103 | Coiled-coil domain containing 103. (265 aa) |
