STRINGSTRING
DOCK8 DOCK8 H2ZV40_LATCH H2ZV40_LATCH LGALS3 LGALS3 LOC102351798 LOC102351798 SLC46A2 SLC46A2 H3B480_LATCH H3B480_LATCH TP53 TP53 PRELID1 PRELID1 EFNA1 EFNA1 FADD FADD LOC102351706 LOC102351706 GPAM GPAM KIFAP3 KIFAP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2039 aa)
H2ZV40_LATCHProtein kinase domain-containing protein. (266 aa)
LGALS3Galectin. (274 aa)
LOC102351798Galectin. (167 aa)
SLC46A2Solute carrier family 46 member 2. (461 aa)
H3B480_LATCHUncharacterized protein. (567 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
PRELID1PRELI domain containing 1. (216 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (176 aa)
FADDFas associated via death domain. (193 aa)
LOC102351706PRELI domain containing 1b. (213 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (854 aa)
KIFAP3Kinesin associated protein 3. (795 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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