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MED13 MED13 ANGPTL3 ANGPTL3 GCKR GCKR SIRT1 SIRT1 PNPLA8 PNPLA8 LIPC LIPC PLA2G12B PLA2G12B FITM2 FITM2 H3B2C8_LATCH H3B2C8_LATCH FUNDC2 FUNDC2 ABCG8 ABCG8 ABCG5 ABCG5 ANGPTL4 ANGPTL4 NR1H4 NR1H4 IL18 IL18 SCARB1 SCARB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2186 aa)
ANGPTL3Angiopoietin like 3. (454 aa)
GCKRGlucokinase regulator. (346 aa)
SIRT1Sirtuin 1. (729 aa)
PNPLA8Patatin like phospholipase domain containing 8. (796 aa)
LIPCLipase C, hepatic type. (503 aa)
PLA2G12BPhospholipase A2 group XIIB. (201 aa)
FITM2Fat storage inducing transmembrane protein 2. (266 aa)
H3B2C8_LATCHUncharacterized protein. (389 aa)
FUNDC2FUN14 domain containing 2. (168 aa)
ABCG8ATP binding cassette subfamily G member 8. (677 aa)
ABCG5ATP binding cassette subfamily G member 5. (438 aa)
ANGPTL4Angiopoietin like 4. (459 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (456 aa)
IL18Uncharacterized protein. (200 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (521 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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