STRINGSTRING
LGALS9 LGALS9 ARG2 ARG2 TIRAP TIRAP LOC102353843 LOC102353843 TGFB1 TGFB1 TLR9 TLR9 LOC102351798 LOC102351798 LGALS3 LGALS3 ITCH ITCH M3XGJ3_LATCH M3XGJ3_LATCH IL18 IL18 LOC102356247 LOC102356247 MAD1L1 MAD1L1 M3XIM8_LATCH M3XIM8_LATCH M3XIR6_LATCH M3XIR6_LATCH HHLA2 HHLA2 NFATC2 NFATC2 MZB1 MZB1 TNFRSF1B TNFRSF1B LOC102348796 LOC102348796 TWSG1 TWSG1 IL6 IL6 H3AHE4_LATCH H3AHE4_LATCH GPAM GPAM SLC7A1 SLC7A1 CD40 CD40 NCK1 NCK1 TRAF6 TRAF6 PTPRC PTPRC BLK BLK CD81 CD81 LOC102348150 LOC102348150 PTPN6 PTPN6 H2ZZ29_LATCH H2ZZ29_LATCH CEBPB CEBPB LOC102346338 LOC102346338 NMBR NMBR GPR183 GPR183 H2ZX10_LATCH H2ZX10_LATCH IRF1 IRF1 H2ZV40_LATCH H2ZV40_LATCH VTCN1 VTCN1 CLCF1 CLCF1 ZAP70 ZAP70 SOS2 SOS2 MARCHF7 MARCHF7 IL12RB2 IL12RB2 TSPAN32 TSPAN32 H3ACR7_LATCH H3ACR7_LATCH PDCD1LG2 PDCD1LG2 GREM1 GREM1 JAK2 JAK2 RPS3 RPS3 LYN LYN LRRC1 LRRC1 TNFSF13B TNFSF13B H3A8Y5_LATCH H3A8Y5_LATCH H3A807_LATCH H3A807_LATCH DLG5 DLG5 ATM ATM IL10 IL10 IGF2 IGF2 TMEM147 TMEM147 RIPK2 RIPK2 TGFBR2 TGFBR2 KIT KIT SOS1 SOS1 H3A3Z5_LATCH H3A3Z5_LATCH CARD11 CARD11 FADD FADD LOC102349920 LOC102349920 CTLA4 CTLA4 LOC102346566 LOC102346566 IL6ST IL6ST TNFRSF9 TNFRSF9 NCK2 NCK2 H3ALU1_LATCH H3ALU1_LATCH RASSF5 RASSF5 LEP LEP SH3RF1 SH3RF1 LOC102358329 LOC102358329 H3ASA2_LATCH H3ASA2_LATCH DHPS DHPS H3AT06_LATCH H3AT06_LATCH NDFIP1 NDFIP1 IKZF3 IKZF3 SYK SYK TMEM131L TMEM131L H3AWB3_LATCH H3AWB3_LATCH PAWR PAWR GPNMB GPNMB INPP5D INPP5D LOC102363504 LOC102363504 H3B0Y6_LATCH H3B0Y6_LATCH SASH3 SASH3 GLMN GLMN CSF1R CSF1R CTNNB1 CTNNB1 VTCN1-2 VTCN1-2 CD276 CD276 CD40LG CD40LG TNFRSF21 TNFRSF21 PELI1 PELI1 CD74 CD74 RC3H1 RC3H1 H3BAW7_LATCH H3BAW7_LATCH H3BAX4_LATCH H3BAX4_LATCH MYD88 MYD88 ATAD5 ATAD5 NF1 NF1 ZNF335 ZNF335
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LGALS9Galectin. (369 aa)
ARG2Arginase. (363 aa)
TIRAPTIR domain containing adaptor protein. (267 aa)
LOC102353843Uncharacterized protein. (335 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
TLR9Toll-like receptor 9. (1039 aa)
LOC102351798Galectin. (167 aa)
LGALS3Galectin. (274 aa)
ITCHE3 ubiquitin-protein ligase. (880 aa)
M3XGJ3_LATCHTNFR-Cys domain-containing protein. (163 aa)
IL18Uncharacterized protein. (200 aa)
LOC102356247Uncharacterized protein. (636 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (684 aa)
M3XIM8_LATCHIg-like domain-containing protein. (241 aa)
M3XIR6_LATCHUncharacterized protein. (269 aa)
HHLA2Ig-like domain-containing protein. (145 aa)
NFATC2Nuclear factor of activated T cells 2. (912 aa)
MZB1Marginal zone B and B1 cell specific protein. (210 aa)
TNFRSF1BTNF receptor superfamily member 1B. (465 aa)
LOC102348796Uncharacterized protein. (497 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (220 aa)
IL6Uncharacterized protein. (149 aa)
H3AHE4_LATCHUncharacterized protein. (463 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (854 aa)
SLC7A1Solute carrier family 7 member 1. (658 aa)
CD40TNFR-Cys domain-containing protein. (167 aa)
NCK1Cytoplasmic protein. (377 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (830 aa)
BLKTyrosine-protein kinase. (447 aa)
CD81Tetraspanin. (184 aa)
LOC102348150Signal transducer and activator of transcription. (786 aa)
PTPN6Protein tyrosine phosphatase non-receptor type 6. (338 aa)
H2ZZ29_LATCHUncharacterized protein. (442 aa)
CEBPBCCAAT/enhancer-binding protein. (291 aa)
LOC102346338ZP domain-containing protein. (328 aa)
NMBRNeuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (396 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (363 aa)
H2ZX10_LATCHUncharacterized protein. (436 aa)
IRF1Interferon regulatory factor. (264 aa)
H2ZV40_LATCHProtein kinase domain-containing protein. (266 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (279 aa)
CLCF1Cardiotrophin like cytokine factor 1. (235 aa)
ZAP70Tyrosine-protein kinase. (609 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1241 aa)
MARCHF7Membrane associated ring-CH-type finger 7. (733 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (836 aa)
TSPAN32Uncharacterized protein. (146 aa)
H3ACR7_LATCHUncharacterized protein. (460 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (247 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (189 aa)
JAK2Tyrosine-protein kinase. (1152 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (254 aa)
LYNTyrosine-protein kinase. (515 aa)
LRRC1Uncharacterized protein. (155 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (122 aa)
H3A8Y5_LATCHUncharacterized protein. (477 aa)
H3A807_LATCHUncharacterized protein. (507 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1821 aa)
ATMATM serine/threonine kinase. (2375 aa)
IL10Interleukin 10. (185 aa)
IGF2Insulin like growth factor 2. (207 aa)
TMEM147Transmembrane protein 147. (225 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (567 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (937 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1331 aa)
H3A3Z5_LATCHUncharacterized protein. (679 aa)
CARD11Caspase recruitment domain family member 11. (1137 aa)
FADDFas associated via death domain. (193 aa)
LOC102349920Uncharacterized protein. (199 aa)
CTLA4IG domain-containing protein. (186 aa)
LOC102346566Annexin. (343 aa)
IL6STInterleukin 6 signal transducer. (922 aa)
TNFRSF9TNF receptor superfamily member 9. (213 aa)
NCK2Cytoplasmic protein. (380 aa)
H3ALU1_LATCHUncharacterized protein. (1358 aa)
RASSF5Ras association domain family member 5. (225 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
SH3RF1SH3 domain containing ring finger 1. (745 aa)
LOC102358329TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (161 aa)
H3ASA2_LATCHIg-like domain-containing protein. (290 aa)
DHPSDeoxyhypusine synthase. (365 aa)
H3AT06_LATCHUncharacterized protein. (88 aa)
NDFIP1Nedd4 family interacting protein 1. (212 aa)
IKZF3IKAROS family zinc finger 3. (507 aa)
SYKTyrosine-protein kinase. (616 aa)
TMEM131LTransmembrane 131 like. (1522 aa)
H3AWB3_LATCHUncharacterized protein. (560 aa)
PAWRUncharacterized protein. (118 aa)
GPNMBGlycoprotein nmb. (607 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1144 aa)
LOC102363504Tyrosine-protein kinase. (1116 aa)
H3B0Y6_LATCHPRKC, apoptosis, WT1, regulator. (191 aa)
SASH3SAM and SH3 domain containing 3. (433 aa)
GLMNGlomulin, FKBP associated protein. (597 aa)
CSF1RColony stimulating factor 1 receptor. (968 aa)
CTNNB1Catenin beta 1. (781 aa)
VTCN1-2Uncharacterized protein. (232 aa)
CD276CD276 molecule. (324 aa)
CD40LGCD40 ligand; Belongs to the tumor necrosis factor family. (284 aa)
TNFRSF21TNF receptor superfamily member 21. (651 aa)
PELI1Pellino E3 ubiquitin protein ligase 1. (445 aa)
CD74CD74 molecule. (279 aa)
RC3H1Ring finger and CCCH-type domains 1. (1123 aa)
H3BAW7_LATCHUncharacterized protein. (190 aa)
H3BAX4_LATCHDC_STAMP domain-containing protein. (450 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
ATAD5ATPase family AAA domain containing 5. (1828 aa)
NF1Neurofibromin 1. (2814 aa)
ZNF335Zinc finger protein 335. (1379 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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