(9 nodes) Left/right axis specification network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HSPB11	Zgc:158640. (142 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	DLL3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (699 aa)
	ARL13B	ADP ribosylation factor like GTPase 13B. (343 aa)
	H3A0S5_LATCH	Uncharacterized protein. (547 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (820 aa)
	SETDB2	SET domain bifurcated histone lysine methyltransferase 2. (751 aa)
	EPB41L5	Erythrocyte membrane protein band 4.1 like 5. (506 aa)
	H3AK63_LATCH	Uncharacterized protein. (2103 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL13B	H3A0S5_LATCH	ENSLACP00000008225	ENSLACP00000003246	ADP ribosylation factor like GTPase 13B.	Uncharacterized protein.	0.624
ARL13B	SMO	ENSLACP00000008225	ENSLACP00000002758	ADP ribosylation factor like GTPase 13B.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.623
DLL1	DLL3	ENSLACP00000009351	ENSLACP00000008690	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.904
DLL3	DLL1	ENSLACP00000008690	ENSLACP00000009351	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.904
H3A0S5_LATCH	ARL13B	ENSLACP00000003246	ENSLACP00000008225	Uncharacterized protein.	ADP ribosylation factor like GTPase 13B.	0.624
SMO	ARL13B	ENSLACP00000002758	ENSLACP00000008225	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	ADP ribosylation factor like GTPase 13B.	0.623