STRINGSTRING
LOC102353948 LOC102353948 FLT1 FLT1 LOC102350846 LOC102350846 RGMA RGMA LOC102352268 LOC102352268 H3BCE1_LATCH H3BCE1_LATCH LOC102366055 LOC102366055 FGF2 FGF2 NTRK3 NTRK3 HIVEP1 HIVEP1 FLRT1 FLRT1 CILP CILP TGFB3 TGFB3 CIB1 CIB1 GDF2 GDF2 FEZ1 FEZ1 H3B924_LATCH H3B924_LATCH NODAL NODAL LOC106701779 LOC106701779 CREB1 CREB1 PAX9 PAX9 WNT2 WNT2 VEGFD VEGFD STMN2 STMN2 NTRK1 NTRK1 H3B7I7_LATCH H3B7I7_LATCH H3B780_LATCH H3B780_LATCH SORT1 SORT1 PIK3CA PIK3CA CLDN1 CLDN1 ITGB5 ITGB5 CLDN5 CLDN5 ZNF831 ZNF831 CTNNB1 CTNNB1 RACK1 RACK1 MSTN MSTN FST FST FGF3 FGF3 H3AWB3_LATCH H3AWB3_LATCH DSTYK DSTYK DDR2 DDR2 HJV HJV H3AVW8_LATCH H3AVW8_LATCH DLL4 DLL4 ADAMTS12 ADAMTS12 ACVR2B ACVR2B FAM83G FAM83G STAT3 STAT3 CHST11 CHST11 LOC102351332 LOC102351332 MTSS2 MTSS2 CLEC3B CLEC3B ANKRD1 ANKRD1 MED1 MED1 LOC102358054 LOC102358054 HTRA2 HTRA2 TMEM100 TMEM100 BDNF BDNF SMAD1 SMAD1 CDH5 CDH5 CITED1 CITED1 RAB14 RAB14 SMAD9 SMAD9 APPL1 APPL1 BAG4 BAG4 BMP6 BMP6 GCLM GCLM SOSTDC1 SOSTDC1 SMAD3 SMAD3 SOST SOST FGF22 FGF22 TRIM71 TRIM71 H3APB2_LATCH H3APB2_LATCH FGF16 FGF16 H3AP47_LATCH H3AP47_LATCH ACVR1 ACVR1 RIPK1 RIPK1 GAREM2 GAREM2 KDR KDR FGFRL1 FGFRL1 MYO1C MYO1C FLCN FLCN H3AM65_LATCH H3AM65_LATCH H3AM01_LATCH H3AM01_LATCH IBSP IBSP RAPGEF2 RAPGEF2 GDF5 GDF5 PDGFRA PDGFRA LOC102346566 LOC102346566 PIK3CD PIK3CD SHCBP1 SHCBP1 GAB1 GAB1 TWSG1 TWSG1 STK16 STK16 LOC102357009 LOC102357009 ACVR1C ACVR1C LOC102367422 LOC102367422 SMAD4 SMAD4 H3AI06_LATCH H3AI06_LATCH ITGB1BP1 ITGB1BP1 SIRT1 SIRT1 LOC102351081 LOC102351081 CEP57 CEP57 H3AGH2_LATCH H3AGH2_LATCH LOC102348760 LOC102348760 ID1 ID1 NRROS NRROS SMAD2 SMAD2 LOC102350487 LOC102350487 SMAD5 SMAD5 HSPB1 HSPB1 TGFBR1 TGFBR1 PTPRK PTPRK SLC33A1 SLC33A1 INPP5K INPP5K BAMBI BAMBI FGF8 FGF8 NTF3 NTF3 TGFB2 TGFB2 H3AD77_LATCH H3AD77_LATCH FGFR2 FGFR2 SFRP2 SFRP2 FKBP8 FKBP8 TGFBR3 TGFBR3 PDE2A PDE2A DDIT4 DDIT4 PTPN11 PTPN11 FRS2 FRS2 MAPKAPK2 MAPKAPK2 ERRFI1 ERRFI1 NKPD1 NKPD1 GDF6 GDF6 SMAD7 SMAD7 GDF7 GDF7 LOC102356182 LOC102356182 RAMP2 RAMP2 SMAD6 SMAD6 SPART SPART NTF4 NTF4 EGR1 EGR1 NUS1 NUS1 PRDM14 PRDM14 LEF1 LEF1 JUN JUN VSTM2A VSTM2A PHOX2B PHOX2B ZYX ZYX IL10 IL10 KIDINS220 KIDINS220 LOC102356523 LOC102356523 WFIKKN2 WFIKKN2 MSX1 MSX1 TGFBR2 TGFBR2 SOS1 SOS1 H3A3Z5_LATCH H3A3Z5_LATCH FLRT3 FLRT3 H3A2B0_LATCH H3A2B0_LATCH BCAR1 BCAR1 URI1 URI1 DTYMK DTYMK GATA3 GATA3 PDGFRL PDGFRL NTRK2 NTRK2 H3A007_LATCH H3A007_LATCH PDGFB PDGFB GATA6 GATA6 LOC102349535 LOC102349535 ACVR2A ACVR2A BMP10 BMP10 EEF2K EEF2K DLX1 DLX1 BMPR1A BMPR1A DLX5 DLX5 GAREM1 GAREM1 H2ZWE3_LATCH H2ZWE3_LATCH GCLC GCLC H2ZW26_LATCH H2ZW26_LATCH LOC102358920 LOC102358920 BMPR1B BMPR1B LOC102364341 LOC102364341 ITGB8 ITGB8 KIF16B KIF16B LOC102351518 LOC102351518 CHRD CHRD GAS1 GAS1 FGFR3 FGFR3 TAB1 TAB1 CCN2 CCN2 ZFYVE27 ZFYVE27 ITGB6 ITGB6 APPL2 APPL2 DDX5 DDX5 BAIAP2 BAIAP2 WWOX WWOX H3B4Z2_LATCH H3B4Z2_LATCH FUT8 FUT8 H3B4J4_LATCH H3B4J4_LATCH H3B4C9_LATCH H3B4C9_LATCH HPGD-2 HPGD-2 SKIL SKIL FGF5 FGF5 ZPR1 ZPR1 PDGFRB PDGFRB TMEM108 TMEM108 DLX3 DLX3 GDF3 GDF3 BMP2 BMP2 FGF7 FGF7 FOXF1 FOXF1 GAS6 GAS6 EPB41L5 EPB41L5 LOC102360711 LOC102360711 LOC102348669 LOC102348669 H3B2C8_LATCH H3B2C8_LATCH UBE3A UBE3A TP53 TP53 ADAMTS7 ADAMTS7 FRS3 FRS3 HAS1 HAS1 NRP2 NRP2 EGR2 EGR2 FGF18 FGF18 FGFR1 FGFR1 FIBP FIBP LOC102361405 LOC102361405 BMP15 BMP15 FGF1 FGF1 PDCD4 PDCD4 CRKL CRKL EGR3 EGR3 FGF20 FGF20 DAB2 DAB2 H3AYQ4_LATCH H3AYQ4_LATCH H3AYC1_LATCH H3AYC1_LATCH ZFP36L2 ZFP36L2 FGF19 FGF19 MAGI2 MAGI2 MAP2K5 MAP2K5 NDNF NDNF FGF4 FGF4 PDCD5 PDCD5 CAV2 CAV2 BMPR2 BMPR2 LOC102351883 LOC102351883 NRP1 NRP1 TNFRSF1B TNFRSF1B VEGFB VEGFB HGF HGF MTMR4 MTMR4 ENG ENG FLT4 FLT4 VEGFC VEGFC LOC102356233 LOC102356233 BMPER BMPER EXT2 EXT2 SOX5 SOX5 LOC102345670 LOC102345670 ZFP36L1 ZFP36L1 LOC102358988 LOC102358988 HPGD HPGD FGFR4 FGFR4 NR4A1 NR4A1 ACVR1B ACVR1B ACVRL1 ACVRL1 BMP4 BMP4 LGMN LGMN PGF PGF MARS1 MARS1 LOC102358538 LOC102358538 LOC102348458 LOC102348458 PPM1A PPM1A NGF NGF RGMB RGMB RAB35 RAB35 LOC102352712 LOC102352712 CAV3 CAV3 USP8 USP8 FOS FOS TGFB1 TGFB1 SETX SETX WNT2B WNT2B FGF6 FGF6 FGF23 FGF23 AKT1S1 AKT1S1 H3BEX6_LATCH H3BEX6_LATCH NLK NLK FLRT2 FLRT2 H3BE69_LATCH H3BE69_LATCH KNSTRN KNSTRN SOX6 SOX6 BMP7 BMP7 RAPGEF1 RAPGEF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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LOC102353948Nemo-like kinase, type 1. (336 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa)
LOC102350846Ig-like domain-containing protein. (257 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (421 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
H3BCE1_LATCHLRRCT domain-containing protein. (341 aa)
LOC102366055Uncharacterized protein. (579 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
NTRK3Tyrosine-protein kinase receptor. (296 aa)
HIVEP1Human immunodeficiency virus type I enhancer binding protein 1. (2614 aa)
FLRT1Fibronectin leucine rich transmembrane protein 1. (648 aa)
CILPCartilage intermediate layer protein. (1183 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
CIB1Calcium and integrin binding 1. (190 aa)
GDF2Growth differentiation factor 2. (431 aa)
FEZ1Fasciculation and elongation protein zeta 1. (393 aa)
H3B924_LATCHTGF_BETA_2 domain-containing protein. (356 aa)
NODALTGF_BETA_2 domain-containing protein. (409 aa)
LOC106701779Uncharacterized protein. (373 aa)
CREB1cAMP responsive element binding protein 1. (347 aa)
PAX9Paired box 9. (342 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (341 aa)
STMN2Stathmin; Belongs to the stathmin family. (179 aa)
NTRK1Tyrosine-protein kinase receptor. (747 aa)
H3B7I7_LATCHSb:cb81. (360 aa)
H3B780_LATCHUncharacterized protein. (370 aa)
SORT1Sortilin. (734 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
CLDN1Claudin 1. (210 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (697 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (213 aa)
ZNF831C2H2-type domain-containing protein. (172 aa)
CTNNB1Catenin beta 1. (781 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
MSTNMyostatin. (372 aa)
FSTFollistatin. (319 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
H3AWB3_LATCHUncharacterized protein. (560 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (848 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (838 aa)
HJVHemojuvelin BMP co-receptor. (404 aa)
H3AVW8_LATCHMothers against decapentaplegic homolog. (369 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (688 aa)
ADAMTS12Peptidase M12B domain-containing protein. (1187 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
FAM83GFamily with sequence similarity 83 member G. (617 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
CHST11Carbohydrate sulfotransferase. (298 aa)
LOC102351332Zgc:158659; Belongs to the PI3/PI4-kinase family. (1067 aa)
MTSS2MTSS I-BAR domain containing 2. (674 aa)
CLEC3BC-type lectin domain family 3 member B. (200 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1401 aa)
LOC102358054Bone morphogenetic protein 8a. (420 aa)
HTRA2HtrA serine peptidase 2. (525 aa)
TMEM100Transmembrane protein 100. (134 aa)
BDNFBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (254 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
CDH5Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (165 aa)
RAB14RAB14, member RAS oncogene family. (234 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (709 aa)
BAG4BCL2 associated athanogene 4. (454 aa)
BMP6Bone morphogenetic protein 6. (428 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)
SOSTDC1Sclerostin domain containing 1. (213 aa)
SMAD3Mothers against decapentaplegic homolog. (358 aa)
SOSTSclerostin. (210 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (99 aa)
TRIM71Tripartite motif containing 71. (841 aa)
H3APB2_LATCHFork-head domain-containing protein. (408 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
H3AP47_LATCHHomeobox domain-containing protein. (204 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (667 aa)
GAREM2GRB2 associated regulator of MAPK1 subtype 2. (809 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa)
FGFRL1Fibroblast growth factor receptor like 1. (480 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1036 aa)
FLCNFolliculin. (576 aa)
H3AM65_LATCHMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (472 aa)
H3AM01_LATCHIntegrin beta; Belongs to the integrin beta chain family. (769 aa)
IBSPUncharacterized protein. (308 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1514 aa)
GDF5Growth differentiation factor 5. (501 aa)
PDGFRAUncharacterized protein. (1094 aa)
LOC102346566Annexin. (343 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1006 aa)
SHCBP1SHC binding and spindle associated 1. (640 aa)
GAB1GRB2 associated binding protein 1. (534 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (220 aa)
STK16Serine/threonine kinase 16. (305 aa)
LOC102357009Southpaw. (414 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
LOC102367422Fibroblast growth factor receptor like 1b. (481 aa)
SMAD4MH2 domain-containing protein. (412 aa)
H3AI06_LATCHKAP NTPase domain-containing protein. (691 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
SIRT1Sirtuin 1. (729 aa)
LOC102351081Bone morphogenetic protein 16. (396 aa)
CEP57Centrosomal protein 57. (496 aa)
H3AGH2_LATCHNeuron-derived neurotrophic factor, like. (567 aa)
LOC102348760Uncharacterized protein. (782 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (131 aa)
NRROSNegative regulator of reactive oxygen species. (691 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
LOC102350487RGM domain family, member D. (443 aa)
SMAD5Mothers against decapentaplegic homolog. (467 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (219 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (565 aa)
SLC33A1Solute carrier family 33 member 1. (541 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (476 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (255 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
H3AD77_LATCHJunE proto-oncogene, AP-1 transcription factor subunit. (316 aa)
FGFR2Fibroblast growth factor receptor. (810 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
FKBP8Peptidylprolyl isomerase. (443 aa)
TGFBR3Transforming growth factor beta receptor 3. (808 aa)
PDE2APhosphodiesterase. (705 aa)
DDIT4DNA damage inducible transcript 4. (222 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (586 aa)
FRS2Fibroblast growth factor receptor substrate 2. (502 aa)
MAPKAPK2MAPK activated protein kinase 2. (332 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (468 aa)
NKPD1NTPase, KAP family P-loop domain containing 1. (547 aa)
GDF6Growth differentiation factor 6a. (408 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
GDF7Growth differentiation factor 7. (416 aa)
LOC102356182Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
RAMP2Uncharacterized protein. (146 aa)
SMAD6Mothers against decapentaplegic homolog. (485 aa)
SPARTSpartin. (664 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (232 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (505 aa)
NUS1NUS1 dehydrodolichyl diphosphate synthase subunit. (276 aa)
PRDM14PR/SET domain 14. (599 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (311 aa)
VSTM2AV-set and transmembrane domain containing 2A. (237 aa)
PHOX2BPaired like homeobox 2B. (287 aa)
ZYXZyxin. (554 aa)
IL10Interleukin 10. (185 aa)
KIDINS220Kinase D interacting substrate 220. (1774 aa)
LOC102356523Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (575 aa)
MSX1Msh homeobox 1. (256 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1331 aa)
H3A3Z5_LATCHUncharacterized protein. (679 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (655 aa)
H3A2B0_LATCHFibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (914 aa)
URI1URI1 prefoldin like chaperone. (494 aa)
DTYMKDeoxythymidylate kinase. (189 aa)
GATA3GATA binding protein 3. (447 aa)
PDGFRLPlatelet derived growth factor receptor like. (377 aa)
NTRK2Tyrosine-protein kinase receptor. (819 aa)
H3A007_LATCHUncharacterized protein. (52 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (209 aa)
GATA6GATA binding protein 6. (503 aa)
LOC102349535Uncharacterized protein. (176 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
BMP10Bone morphogenetic protein 10. (405 aa)
EEF2KEukaryotic elongation factor 2 kinase. (512 aa)
DLX1Distal-less homeobox 1. (253 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
DLX5Distal-less homeobox 5. (290 aa)
GAREM1GRB2 associated regulator of MAPK1 subtype 1. (883 aa)
H2ZWE3_LATCHUncharacterized protein. (222 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (655 aa)
H2ZW26_LATCHUncharacterized protein. (352 aa)
LOC102358920Programmed cell death 4a. (244 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC102364341Uncharacterized protein. (271 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (637 aa)
KIF16BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1321 aa)
LOC102351518Left-right determination factor. (364 aa)
CHRDChordin; Belongs to the chordin family. (948 aa)
GAS1Growth arrest specific 1. (259 aa)
FGFR3Fibroblast growth factor receptor. (778 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (436 aa)
CCN2Cellular communication network factor 2. (344 aa)
ZFYVE27Uncharacterized protein. (280 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (675 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (484 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (512 aa)
BAIAP2BAI1 associated protein 2. (434 aa)
WWOXWW domain containing oxidoreductase. (353 aa)
H3B4Z2_LATCHPep_M12B_propep domain-containing protein. (169 aa)
FUT8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (577 aa)
H3B4J4_LATCHUncharacterized protein. (982 aa)
H3B4C9_LATCHPDZ domain-containing protein. (105 aa)
HPGD-2Uncharacterized protein. (86 aa)
SKILSKI like proto-oncogene. (691 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ZPR1ZPR1 zinc finger. (470 aa)
PDGFRBPlatelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1103 aa)
TMEM108Transmembrane protein 108. (355 aa)
DLX3Distal-less homeobox 3. (282 aa)
GDF3Growth differentiation factor 3. (381 aa)
BMP2Bone morphogenetic protein 2. (402 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FOXF1Forkhead box F1. (381 aa)
GAS6Uncharacterized protein. (681 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (506 aa)
LOC102360711PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (299 aa)
LOC102348669B box-type domain-containing protein. (585 aa)
H3B2C8_LATCHUncharacterized protein. (389 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (907 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1594 aa)
FRS3Fibroblast growth factor receptor substrate 3. (516 aa)
HAS1Hyaluronan synthase 1. (568 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (929 aa)
EGR2Early growth response 2. (433 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FGFR1Fibroblast growth factor receptor. (824 aa)
FIBPFGF1 intracellular binding protein. (367 aa)
LOC102361405PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (140 aa)
BMP15Bone morphogenetic protein 15. (394 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PDCD4Programmed cell death 4. (466 aa)
CRKLCRK like proto-oncogene, adaptor protein. (219 aa)
EGR3Early growth response 3. (384 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
DAB2DAB adaptor protein 2. (745 aa)
H3AYQ4_LATCHUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1220 aa)
H3AYC1_LATCHUncharacterized protein. (301 aa)
ZFP36L2Uncharacterized protein. (394 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
MAGI2Uncharacterized protein. (397 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
NDNFNeuron derived neurotrophic factor. (571 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
PDCD5Programmed cell death 5. (128 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (163 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
LOC102351883Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2505 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (928 aa)
TNFRSF1BTNF receptor superfamily member 1B. (465 aa)
VEGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (148 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (720 aa)
MTMR4Myotubularin related protein 4. (1171 aa)
ENGEndoglin. (674 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1394 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (410 aa)
LOC102356233TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (574 aa)
BMPERBMP binding endothelial regulator. (682 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (718 aa)
SOX5SRY-box transcription factor 5. (757 aa)
LOC102345670Sortilin. (809 aa)
ZFP36L1ZFP36 ring finger protein like 1. (346 aa)
LOC102358988Mothers against decapentaplegic homolog. (614 aa)
HPGD15-hydroxyprostaglandin dehydrogenase. (165 aa)
FGFR4Fibroblast growth factor receptor. (810 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (580 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (489 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (497 aa)
BMP4Bone morphogenetic protein 4. (460 aa)
LGMNLegumain. (436 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (132 aa)
MARS1Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (905 aa)
LOC102358538Growth differentiation factor 11. (381 aa)
LOC102348458Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (383 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (272 aa)
RGMBRepulsive guidance molecule BMP co-receptor b. (459 aa)
RAB35RAB35, member RAS oncogene family. (203 aa)
LOC102352712Protein tyrosine phosphatase non-receptor type 11b. (553 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1102 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (391 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
SETXSenataxin. (2165 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (249 aa)
AKT1S1AKT1 substrate 1. (285 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
NLKMitogen-activated protein kinase. (382 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (656 aa)
H3BE69_LATCHPID domain-containing protein. (136 aa)
KNSTRNUncharacterized protein. (183 aa)
SOX6SRY-box transcription factor 6. (814 aa)
BMP7Bone morphogenetic protein 7. (425 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1217 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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