(7 nodes) Cellular response to follicle-stimulating hormone stimulus network (Latimeria chalumnae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GCLC	Glutamate-cysteine ligase catalytic subunit. (655 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
	GATA1	GATA binding protein 1b. (432 aa)
	GCLM	Glutamate-cysteine ligase modifier subunit. (274 aa)
	LOC102356870	Uncharacterized protein. (744 aa)
	EFNA5	Ephrin A5; Belongs to the ephrin family. (185 aa)
	EDN1	Endothelin 1. (216 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDN1	EDNRA	ENSLACP00000018825	ENSLACP00000006100	Endothelin 1.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.999
EDNRA	EDN1	ENSLACP00000006100	ENSLACP00000018825	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.999
EFNA5	LOC102356870	ENSLACP00000018748	ENSLACP00000013164	Ephrin A5; Belongs to the ephrin family.	Uncharacterized protein.	0.848
GCLC	GCLM	ENSLACP00000001656	ENSLACP00000012373	Glutamate-cysteine ligase catalytic subunit.	Glutamate-cysteine ligase modifier subunit.	0.998
GCLM	GCLC	ENSLACP00000012373	ENSLACP00000001656	Glutamate-cysteine ligase modifier subunit.	Glutamate-cysteine ligase catalytic subunit.	0.998
LOC102356870	EFNA5	ENSLACP00000013164	ENSLACP00000018748	Uncharacterized protein.	Ephrin A5; Belongs to the ephrin family.	0.848