STRINGSTRING
KCNE1 KCNE1 DAG1 DAG1 ERCC2 ERCC2 FEV FEV ADAMTS7 ADAMTS7 MTHFSD MTHFSD CNTN2 CNTN2 BHLHA15 BHLHA15 PHOSPHO2 PHOSPHO2 SCLT1 SCLT1 CATSPER2 CATSPER2 ADGRL1-2 ADGRL1-2 ADAMTS12 ADAMTS12 VSX1 VSX1 TGFB1 TGFB1 ZBTB16 ZBTB16 WDR77 WDR77 DDIT3 DDIT3 WNT1 WNT1 H3BIS0_LATCH H3BIS0_LATCH MAEA MAEA TDRD1 TDRD1 CATSPER4 CATSPER4 EPO EPO DMC1 DMC1 G6PD G6PD ROPN1L ROPN1L CATSPERD CATSPERD CCR6 CCR6 EFCAB9 EFCAB9 M3XLI6_LATCH M3XLI6_LATCH C1QA C1QA PHOSPHO1 PHOSPHO1 LOC102345793 LOC102345793 LOC102366200 LOC102366200 SLC26A3 SLC26A3 MYOC MYOC KDR KDR FBXO5 FBXO5 GLDN GLDN FARP2 FARP2 ZBTB7A ZBTB7A H3AR20_LATCH H3AR20_LATCH IFT80 IFT80 CDK5R1 CDK5R1 TUT4 TUT4 TDRD6 TDRD6 CDH5 CDH5 MECP2 MECP2 LOC102357170 LOC102357170 B4GALT6 B4GALT6 LOC102356870 LOC102356870 PLD6 PLD6 NTN4 NTN4 H2ZSI1_LATCH H2ZSI1_LATCH NOM1 NOM1 SCARF1 SCARF1 AXL AXL LOC102354477 LOC102354477 TRPC4AP TRPC4AP TUSC2 TUSC2 TDRKH TDRKH HOXA5 HOXA5 B4GALT5 B4GALT5 ABHD2 ABHD2 H2ZTF7_LATCH H2ZTF7_LATCH H2ZTK5_LATCH H2ZTK5_LATCH FEM1B FEM1B APP APP H2ZWA4_LATCH H2ZWA4_LATCH TUT7 TUT7 H2ZX66_LATCH H2ZX66_LATCH EPAS1 EPAS1 H3A0R0_LATCH H3A0R0_LATCH CFTR CFTR GATA3 GATA3 FAM20C FAM20C SEMA4D SEMA4D GPAT4 GPAT4 RET RET RB1 RB1 CATSPER3 CATSPER3 EDNRA EDNRA TDRD5 TDRD5 KDM1A KDM1A CBFB CBFB H3AFZ1_LATCH H3AFZ1_LATCH RECK RECK H3AGP4_LATCH H3AGP4_LATCH BFSP2 BFSP2 LOC102360035 LOC102360035 H3AHQ6_LATCH H3AHQ6_LATCH THBS3 THBS3 LYL1 LYL1 NF1 NF1 RND1 RND1 SOX8 SOX8 EDN1 EDN1 CDK5R2 CDK5R2 H3B9R0_LATCH H3B9R0_LATCH LOC102365238 LOC102365238 HOXB13 HOXB13 CTNNB1 CTNNB1 ANKRD17 ANKRD17 H3B4Z2_LATCH H3B4Z2_LATCH TDRD7 TDRD7 TDRD10 TDRD10 SNX10 SNX10 TDRD15 TDRD15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNE1Uncharacterized protein. (122 aa)
DAG1Dystroglycan 1. (900 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (611 aa)
FEVFEV transcription factor, ETS family member. (230 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1594 aa)
MTHFSDMethenyltetrahydrofolate synthetase domain containing. (406 aa)
CNTN2Contactin 2. (1026 aa)
BHLHA15Basic helix-loop-helix family member a15. (177 aa)
PHOSPHO2Phosphatase, orphan 2. (243 aa)
SCLT1Sodium channel and clathrin linker 1. (698 aa)
CATSPER2Cation channel sperm associated 2. (460 aa)
ADGRL1-2Uncharacterized protein. (774 aa)
ADAMTS12Peptidase M12B domain-containing protein. (1187 aa)
VSX1Visual system homeobox 1. (347 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
ZBTB16Zinc finger and BTB domain containing 16. (420 aa)
WDR77WD repeat domain 77. (322 aa)
DDIT3DNA damage inducible transcript 3. (256 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
H3BIS0_LATCHUncharacterized protein. (153 aa)
MAEAMacrophage erythroblast attacher. (287 aa)
TDRD1Tudor domain containing 1. (1170 aa)
CATSPER4Cation channel sperm associated 4. (443 aa)
EPOErythropoietin. (179 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (317 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
ROPN1LRhophilin associated tail protein 1 like. (218 aa)
CATSPERDUncharacterized protein. (457 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (397 aa)
EFCAB9EF-hand calcium binding domain 9. (223 aa)
M3XLI6_LATCHUncharacterized protein. (426 aa)
C1QAComplement C1q A chain. (241 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
LOC102345793Si:dkeyp-92c9.2. (294 aa)
LOC102366200Uncharacterized protein; Belongs to the semaphorin family. (627 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (669 aa)
MYOCMyocilin. (272 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa)
FBXO5F-box protein 5. (313 aa)
GLDNGliomedin. (534 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (697 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (518 aa)
H3AR20_LATCHUncharacterized protein. (578 aa)
IFT80Intraflagellar transport 80. (780 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (306 aa)
TUT4Terminal uridylyl transferase 4. (1706 aa)
TDRD6Tudor domain containing 6. (1667 aa)
CDH5Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
MECP2Methyl-CpG binding protein 2. (459 aa)
LOC102357170Uncharacterized protein. (614 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (387 aa)
LOC102356870Uncharacterized protein. (744 aa)
PLD6Phospholipase D family member 6. (218 aa)
NTN4Netrin 4. (345 aa)
H2ZSI1_LATCHLisH domain-containing protein. (105 aa)
NOM1Nucleolar protein with MIF4G domain 1. (826 aa)
SCARF1Scavenger receptor class F member 1. (759 aa)
AXLAXL receptor tyrosine kinase. (872 aa)
LOC102354477Uncharacterized protein. (838 aa)
TRPC4APTransient receptor potential cation channel subfamily C member 4 associated protein. (776 aa)
TUSC2Tumor suppressor 2, mitochondrial calcium regulator. (111 aa)
TDRKHTudor and KH domain containing. (417 aa)
HOXA5Homeobox A5. (269 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (340 aa)
ABHD2Abhydrolase domain containing 2. (431 aa)
H2ZTF7_LATCHFam20C domain-containing protein. (511 aa)
H2ZTK5_LATCHPeptidase_M50 domain-containing protein. (221 aa)
FEM1BFem-1 homolog B. (667 aa)
APPAmyloid beta precursor protein. (652 aa)
H2ZWA4_LATCHUncharacterized protein. (297 aa)
TUT7Terminal uridylyl transferase 7. (1545 aa)
H2ZX66_LATCHUncharacterized protein. (641 aa)
EPAS1Endothelial PAS domain protein 1. (861 aa)
H3A0R0_LATCHEph LBD domain-containing protein. (229 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1491 aa)
GATA3GATA binding protein 3. (447 aa)
FAM20CFam20C domain-containing protein. (305 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (455 aa)
RETRet proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1090 aa)
RB1Uncharacterized protein. (411 aa)
CATSPER3Cation channel sperm associated 3. (334 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
TDRD5Tudor domain containing 5. (685 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (820 aa)
CBFBCore-binding factor subunit beta. (189 aa)
H3AFZ1_LATCHPeptidase S72 domain-containing protein. (633 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (952 aa)
H3AGP4_LATCHTower domain-containing protein. (1245 aa)
BFSP2Beaded filament structural protein 2; Belongs to the intermediate filament family. (422 aa)
LOC102360035RIIa domain-containing protein. (186 aa)
H3AHQ6_LATCHEBP cholestenol delta-isomerase. (131 aa)
THBS3Thrombospondin 3. (930 aa)
LYL1BHLH domain-containing protein. (242 aa)
NF1Neurofibromin 1. (2814 aa)
RND1Rho family GTPase 1. (321 aa)
SOX8SRY-box transcription factor 8. (477 aa)
EDN1Endothelin 1. (216 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (325 aa)
H3B9R0_LATCHUncharacterized protein. (128 aa)
LOC102365238Ribosomal protein S6 kinase. (740 aa)
HOXB13Homeobox B13. (306 aa)
CTNNB1Catenin beta 1. (781 aa)
ANKRD17Ankyrin repeat domain 17. (2394 aa)
H3B4Z2_LATCHPep_M12B_propep domain-containing protein. (169 aa)
TDRD7Tudor domain containing 7. (1111 aa)
TDRD10Tudor domain containing 10. (357 aa)
SNX10Sorting nexin 10. (203 aa)
TDRD15Tudor domain containing 15. (1602 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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