(21 nodes) Regulation of cell migration involved in sprouting angiogenesis network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	THBS1	Thrombospondin 1. (1170 aa)
	FBXW7	F-box and WD repeat domain containing 7. (713 aa)
	LOC102346566	Annexin. (343 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa)
	SPRED1	Sprouty related EVH1 domain containing 1. (446 aa)
	FBXW9	F-box and WD repeat domain containing 9. (465 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (688 aa)
	PDCD10	Programmed cell death 10. (210 aa)
	MAP3K3	Mitogen-activated protein kinase kinase kinase 3. (658 aa)
	MAP2K5	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
	MEOX2	Mesenchyme homeobox 2. (295 aa)
	TBXA2R	Thromboxane A2 receptor. (351 aa)
	NR2E1	Nuclear receptor subfamily 2 group E member 1. (477 aa)
	LOC102350357	Uncharacterized protein. (577 aa)
	H2ZZY5_LATCH	Uncharacterized protein. (548 aa)
	CIB1	Calcium and integrin binding 1. (190 aa)
	MMRN2	Multimerin 2. (911 aa)
	CARD10	Caspase recruitment domain family member 10. (1063 aa)
	JCAD	Junctional cadherin 5 associated. (1240 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (200 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLL4	KDR	ENSLACP00000013765	ENSLACP00000011126	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.531
FGF2	KDR	ENSLACP00000019200	ENSLACP00000011126	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.879
ITGB1BP1	PDCD10	ENSLACP00000009080	ENSLACP00000013998	Integrin subunit beta 1 binding protein 1.	Programmed cell death 10.	0.685
KDR	DLL4	ENSLACP00000011126	ENSLACP00000013765	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.531
KDR	FGF2	ENSLACP00000011126	ENSLACP00000019200	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.879
LOC102350357	MAP2K5	ENSLACP00000018303	ENSLACP00000014381	Uncharacterized protein.	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.	0.909
LOC102350357	MAP3K3	ENSLACP00000018303	ENSLACP00000014058	Uncharacterized protein.	Mitogen-activated protein kinase kinase kinase 3.	0.901
LOC102350357	PDCD10	ENSLACP00000018303	ENSLACP00000013998	Uncharacterized protein.	Programmed cell death 10.	0.409
MAP2K5	LOC102350357	ENSLACP00000014381	ENSLACP00000018303	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.909
MAP2K5	MAP3K3	ENSLACP00000014381	ENSLACP00000014058	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 3.	0.901
MAP3K3	LOC102350357	ENSLACP00000014058	ENSLACP00000018303	Mitogen-activated protein kinase kinase kinase 3.	Uncharacterized protein.	0.901
MAP3K3	MAP2K5	ENSLACP00000014058	ENSLACP00000014381	Mitogen-activated protein kinase kinase kinase 3.	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.	0.901
MAP3K3	PDCD10	ENSLACP00000014058	ENSLACP00000013998	Mitogen-activated protein kinase kinase kinase 3.	Programmed cell death 10.	0.409
PDCD10	ITGB1BP1	ENSLACP00000013998	ENSLACP00000009080	Programmed cell death 10.	Integrin subunit beta 1 binding protein 1.	0.685
PDCD10	LOC102350357	ENSLACP00000013998	ENSLACP00000018303	Programmed cell death 10.	Uncharacterized protein.	0.409
PDCD10	MAP3K3	ENSLACP00000013998	ENSLACP00000014058	Programmed cell death 10.	Mitogen-activated protein kinase kinase kinase 3.	0.409