STRINGSTRING
RAD51C RAD51C CDC16 CDC16 H2ZSY2_LATCH H2ZSY2_LATCH NCAPH NCAPH LOC102366597 LOC102366597 CDT1 CDT1 PLRG1 PLRG1 NCAPH2 NCAPH2 PIWIL2 PIWIL2 SMPD3 SMPD3 CDC73 CDC73 APP APP H2ZWA0_LATCH H2ZWA0_LATCH FEN1 FEN1 LOC102366946 LOC102366946 NCAPG2 NCAPG2 LOC102367471 LOC102367471 DRD3 DRD3 SMC5 SMC5 AIF1 AIF1 PDGFB PDGFB H3A0V9_LATCH H3A0V9_LATCH MAP3K20 MAP3K20 PCID2 PCID2 PPP1R10 PPP1R10 BTC BTC POLDIP2 POLDIP2 MSX1 MSX1 SLF2 SLF2 CUL4A CUL4A LOC102365031 LOC102365031 IGF2 IGF2 MAD2L1BP MAD2L1BP CUL4B CUL4B RB1 RB1 ANAPC11 ANAPC11 PAGR1 PAGR1 THOC5 THOC5 DDX11 DDX11 CDCA5 CDCA5 CDC25B CDC25B FGF8 FGF8 MBLAC1 MBLAC1 LOC102361922 LOC102361922 MAD2L1 MAD2L1 LOC102348760 LOC102348760 LOC102367082 LOC102367082 RRM1 RRM1 CPSF3 CPSF3 LOC102345131 LOC102345131 UBXN2B UBXN2B INO80 INO80 XRCC3 XRCC3 H3AJV2_LATCH H3AJV2_LATCH CEP120 CEP120 LOC102346566 LOC102346566 CSPP1 CSPP1 KIF14 KIF14 ADAM17 ADAM17 H3AM65_LATCH H3AM65_LATCH CD28 CD28 FBXO5 FBXO5 CDC7 CDC7 CDC14B CDC14B SMC4 SMC4 ATRX ATRX CENPV CENPV STIL STIL TFDP1 TFDP1 EPGN EPGN H3ASN6_LATCH H3ASN6_LATCH NUMA1 NUMA1 MECP2 MECP2 KLHL18 KLHL18 RRM2 RRM2 PAF1 PAF1 H3ATF5_LATCH H3ATF5_LATCH MED1 MED1 NSFL1C NSFL1C MACROH2A1 MACROH2A1 RGCC RGCC DDR2 DDR2 KIF23 KIF23 MEPCE MEPCE H3AWZ8_LATCH H3AWZ8_LATCH ECT2 ECT2 SASS6 SASS6 GIPC2 GIPC2 WIZ WIZ GPSM2 GPSM2 CCND1 CCND1 DBF4 DBF4 LOC102345953 LOC102345953 STXBP4 STXBP4 H3B0I5_LATCH H3B0I5_LATCH MAPK15 MAPK15 DYNC1H1 DYNC1H1 PRDM7 PRDM7 E2F7 E2F7 CHEK2 CHEK2 CDC14A CDC14A FBXO42 FBXO42 GEN1 GEN1 THOC1 THOC1 GIPC3 GIPC3 ANKRD17 ANKRD17 USP19 USP19 FAM83D FAM83D CDC27 CDC27 TPR TPR SLF1 SLF1 LSM11 LSM11 ROCK2 ROCK2 MTBP MTBP CDC42 CDC42 LSM10 LSM10 KMT2E KMT2E H3B8G4_LATCH H3B8G4_LATCH ANAPC7 ANAPC7 E2F8 E2F8 RCC2 RCC2 PLK4 PLK4 STOX1 STOX1 SVIL SVIL LOC102350363 LOC102350363 EDN1 EDN1 GIPC1 GIPC1 H3BAV2_LATCH H3BAV2_LATCH ATAD5 ATAD5 PBK PBK CXCR5 CXCR5 MAP10 MAP10 RAD51B RAD51B CDC23 CDC23 CUL3 CUL3 HOXA13 HOXA13 CDC25C CDC25C RANBP1 RANBP1 CCND2 CCND2 TGFA TGFA RACGAP1 RACGAP1 DRD2 DRD2 CIT CIT ANAPC5 ANAPC5 LRP5 LRP5 UBE2C UBE2C GLI1 GLI1 NCAPG NCAPG RHNO1 RHNO1 CDK1 CDK1 DYNC1LI1 DYNC1LI1 MAD1L1 MAD1L1 RPTOR RPTOR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAD51CRAD51 paralog C. (368 aa)
CDC16Cell division cycle 16. (545 aa)
H2ZSY2_LATCHUncharacterized protein. (345 aa)
NCAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (728 aa)
LOC102366597SMC_N domain-containing protein. (374 aa)
CDT1Chromatin licensing and DNA replication factor 1. (520 aa)
PLRG1Pleiotropic regulator 1. (514 aa)
NCAPH2Non-SMC condensin II complex subunit H2. (617 aa)
PIWIL2Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (954 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (657 aa)
CDC73Cell division cycle 73. (316 aa)
APPAmyloid beta precursor protein. (652 aa)
H2ZWA0_LATCHUncharacterized protein. (591 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (317 aa)
LOC102366946Uncharacterized protein. (358 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1154 aa)
LOC102367471Uncharacterized protein; Belongs to the cyclin family. (292 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (443 aa)
SMC5AAA_23 domain-containing protein. (1096 aa)
AIF1Allograft inflammatory factor 1. (119 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (209 aa)
H3A0V9_LATCHDUF5595 domain-containing protein. (661 aa)
MAP3K20Uncharacterized protein. (792 aa)
PCID2PCI domain containing 2. (452 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (792 aa)
BTCEGF-like domain-containing protein. (177 aa)
POLDIP2DNA polymerase delta interacting protein 2. (369 aa)
MSX1Msh homeobox 1. (256 aa)
SLF2Uncharacterized protein. (597 aa)
CUL4ACullin 4A; Belongs to the cullin family. (851 aa)
LOC102365031ApaG domain-containing protein. (345 aa)
IGF2Insulin like growth factor 2. (207 aa)
MAD2L1BPMAD2L1 binding protein. (419 aa)
CUL4BCullin 4B; Belongs to the cullin family. (845 aa)
RB1Uncharacterized protein. (411 aa)
ANAPC11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
PAGR1PAXIP1 associated glutamate rich protein 1. (188 aa)
THOC5THO complex 5. (734 aa)
DDX11DEAD/H-box helicase 11. (909 aa)
CDCA5Uncharacterized protein. (133 aa)
CDC25BCell division cycle 25B. (582 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
MBLAC1Metallo-beta-lactamase domain containing 1. (216 aa)
LOC102361922Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family. (448 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (202 aa)
LOC102348760Uncharacterized protein. (782 aa)
LOC102367082XPGI domain-containing protein. (317 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (763 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (689 aa)
LOC102345131Si:ch1073-416j23.1. (581 aa)
UBXN2BUBX domain protein 2B. (298 aa)
INO80INO80 complex ATPase subunit. (1542 aa)
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (358 aa)
H3AJV2_LATCHPHD-type domain-containing protein. (679 aa)
CEP120Centrosomal protein 120. (499 aa)
LOC102346566Annexin. (343 aa)
CSPP1Centrosome and spindle pole associated protein 1. (1171 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1644 aa)
ADAM17ADAM metallopeptidase domain 17. (827 aa)
H3AM65_LATCHMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (472 aa)
CD28Ig-like domain-containing protein. (202 aa)
FBXO5F-box protein 5. (313 aa)
CDC7Cell division cycle 7. (560 aa)
CDC14BCell division cycle 14B. (459 aa)
SMC4Structural maintenance of chromosomes protein. (1297 aa)
ATRXATRX chromatin remodeler. (2488 aa)
CENPVCentromere protein V. (159 aa)
STILSTIL centriolar assembly protein. (1298 aa)
TFDP1Transcription factor. (412 aa)
EPGNEpithelial mitogen. (161 aa)
H3ASN6_LATCHHP domain-containing protein. (111 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2155 aa)
MECP2Methyl-CpG binding protein 2. (459 aa)
KLHL18Kelch like family member 18. (577 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (389 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (530 aa)
H3ATF5_LATCHCdc6_C domain-containing protein. (525 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1401 aa)
NSFL1CNSFL1 cofactor. (370 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (370 aa)
RGCCRegulator of cell cycle. (127 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (838 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (961 aa)
MEPCEMethylphosphate capping enzyme. (437 aa)
H3AWZ8_LATCHUncharacterized protein. (385 aa)
ECT2Epithelial cell transforming 2. (919 aa)
SASS6SAS-6 centriolar assembly protein. (567 aa)
GIPC2GIPC PDZ domain containing family member 2. (327 aa)
WIZWIZ zinc finger. (1428 aa)
GPSM2G protein signaling modulator 2, like. (663 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (292 aa)
DBF4DBF4 zinc finger. (672 aa)
LOC102345953Cyclin D3; Belongs to the cyclin family. (292 aa)
STXBP4Syntaxin binding protein 4. (703 aa)
H3B0I5_LATCHDBF4-type domain-containing protein. (315 aa)
MAPK15Mitogen-activated protein kinase 15. (572 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4615 aa)
PRDM7PR/SET domain 7. (233 aa)
E2F7Uncharacterized protein. (373 aa)
CHEK2Checkpoint kinase 2. (411 aa)
CDC14AUncharacterized protein. (612 aa)
FBXO42F-box protein 42. (721 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (899 aa)
THOC1THO complex 1. (656 aa)
GIPC3GIPC PDZ domain containing family member 3. (319 aa)
ANKRD17Ankyrin repeat domain 17. (2394 aa)
USP19Ubiquitin specific peptidase 19. (1382 aa)
FAM83DFamily with sequence similarity 83 member D. (587 aa)
CDC27Cell division cycle 27. (833 aa)
TPRTranslocated promoter region, nuclear basket protein. (2360 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1063 aa)
LSM11LSM11, U7 small nuclear RNA associated. (338 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1462 aa)
MTBPMDM2 binding protein. (877 aa)
CDC42Cell division cycle 42. (156 aa)
LSM10LSM10, U7 small nuclear RNA associated. (130 aa)
KMT2ELysine methyltransferase 2E. (1846 aa)
H3B8G4_LATCHUncharacterized protein. (110 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
E2F8E2F transcription factor 8. (851 aa)
RCC2Regulator of chromosome condensation 2. (498 aa)
PLK4Polo like kinase 4. (982 aa)
STOX1Storkhead box 1. (891 aa)
SVILSupervillin. (2196 aa)
LOC102350363Structural maintenance of chromosomes 2. (656 aa)
EDN1Endothelin 1. (216 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
H3BAV2_LATCHUncharacterized protein. (105 aa)
ATAD5ATPase family AAA domain containing 5. (1828 aa)
PBKPDZ binding kinase. (336 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (373 aa)
MAP10HPHLAWLY domain-containing protein. (862 aa)
RAD51BRAD51 paralog B. (250 aa)
CDC23Cell division cycle 23. (581 aa)
CUL3Cullin 3; Belongs to the cullin family. (769 aa)
HOXA13Homeobox A13b. (295 aa)
CDC25CCell division cycle 25C. (561 aa)
RANBP1RAN binding protein 1. (216 aa)
CCND2Cyclin D2, b; Belongs to the cyclin family. (291 aa)
TGFATransforming growth factor alpha. (140 aa)
RACGAP1Rac GTPase activating protein 1. (635 aa)
DRD2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2066 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1598 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
GLI1GLI family zinc finger 1. (1380 aa)
NCAPGNon-SMC condensin I complex subunit G. (1067 aa)
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (319 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (502 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (684 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1334 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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