STRINGSTRING
H3B0X9_LATCH H3B0X9_LATCH SDHAF2 SDHAF2 CTNNBIP1 CTNNBIP1 SFRP2 SFRP2 GSK3A GSK3A TMEM64 TMEM64 TMEM170B TMEM170B TLE3 TLE3 TMEM88 TMEM88 CBY1 CBY1 APC2 APC2 TNN TNN CSNK1A1 CSNK1A1 SFRP1 SFRP1 H3ANQ8_LATCH H3ANQ8_LATCH H3AP48_LATCH H3AP48_LATCH BICC1 BICC1 SOST SOST NOTUM NOTUM SOSTDC1 SOSTDC1 DKK3 DKK3 H3AT06_LATCH H3AT06_LATCH GSK3B GSK3B LOC102346563 LOC102346563 STK11 STK11 AXIN1 AXIN1 NKD1 NKD1 TMEM131L TMEM131L H3AXS1_LATCH H3AXS1_LATCH DAB2 DAB2 LOC102356408 LOC102356408 LOC102356682 LOC102356682 GREM1 GREM1 SFRP5 SFRP5 CTHRC1 CTHRC1 JADE1 JADE1 TLE5 TLE5 PFDN5 PFDN5 DKK4 DKK4 LOC102346785 LOC102346785 ZNRF3-2 ZNRF3-2 NKX2-5 NKX2-5 CTNNB1 CTNNB1 H3B5P8_LATCH H3B5P8_LATCH ZNRF3 ZNRF3 KREMEN1 KREMEN1 AMER1 AMER1 AMER2 AMER2 TLE4 TLE4 LOC102356742 LOC102356742 IGFBP6 IGFBP6 LOC102355199 LOC102355199 LOC102354118 LOC102354118 SCYL2 SCYL2 AXIN2 AXIN2 H3BE69_LATCH H3BE69_LATCH RUVBL2 RUVBL2 G3BP1 G3BP1 FRMD8 FRMD8 H3BFW7_LATCH H3BFW7_LATCH H3BFZ2_LATCH H3BFZ2_LATCH CAV3 CAV3 MDK MDK SOX9 SOX9 DACT1 DACT1 DDIT3 DDIT3 GLI1 GLI1 NPHP4 NPHP4 TMEM88B TMEM88B DRAXIN DRAXIN TLE1 TLE1 LOC102356000 LOC102356000 OTUD5 OTUD5 LOC102359396 LOC102359396 PTPRO PTPRO LOC102346204 LOC102346204 FZD4 FZD4 STK4 STK4 NKD2 NKD2 LZTS2 LZTS2 MCC MCC GLI3 GLI3 SOX10 SOX10 FRZB FRZB TPBG TPBG LOC102358266 LOC102358266 SFRP4 SFRP4 APC APC LOC102365523 LOC102365523 DKK2 DKK2 WNT11 WNT11 ANKRD6 ANKRD6 H3AJR0_LATCH H3AJR0_LATCH LATS2 LATS2 NPHP3 NPHP3 SOX13 SOX13 H3AMA1_LATCH H3AMA1_LATCH CYLD CYLD SFRP1-2 SFRP1-2 H3ANG8_LATCH H3ANG8_LATCH LATS1 LATS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H3B0X9_LATCHUncharacterized protein. (786 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
GSK3AGlycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (463 aa)
TMEM64Transmembrane protein 64. (350 aa)
TMEM170BTransmembrane protein 170B. (153 aa)
TLE3TLE family member 3, transcriptional corepressor. (761 aa)
TMEM88Transmembrane protein 88 b. (177 aa)
CBY1Uncharacterized protein. (127 aa)
APC2APC regulator of WNT signaling pathway 2. (2366 aa)
TNNTenascin N. (831 aa)
CSNK1A1Casein kinase 1 alpha 1. (287 aa)
SFRP1NTR domain-containing protein. (128 aa)
H3ANQ8_LATCHMCC-bdg_PDZ domain-containing protein. (754 aa)
H3AP48_LATCHDickkopf_N domain-containing protein. (253 aa)
BICC1BicC family RNA binding protein 1. (869 aa)
SOSTSclerostin. (210 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (506 aa)
SOSTDC1Sclerostin domain containing 1. (213 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (349 aa)
H3AT06_LATCHUncharacterized protein. (88 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
LOC102346563Protein tyrosine phosphatase receptor type Ua. (913 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
AXIN1Axin 1. (880 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (370 aa)
TMEM131LTransmembrane 131 like. (1522 aa)
H3AXS1_LATCHProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (313 aa)
DAB2DAB adaptor protein 2. (745 aa)
LOC102356408Uncharacterized protein. (711 aa)
LOC102356682TLE family member 2, transcriptional corepressor b. (743 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (189 aa)
SFRP5Secreted frizzled related protein 5. (309 aa)
CTHRC1Collagen triple helix repeat containing 1. (151 aa)
JADE1Jade family PHD finger 1. (864 aa)
TLE5TLE family member 5, transcriptional modulator. (202 aa)
PFDN5Prefoldin subunit 5. (155 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (222 aa)
LOC102346785Trophoblast glycoprotein a. (373 aa)
ZNRF3-2Uncharacterized protein. (79 aa)
NKX2-5NK2 homeobox 5. (296 aa)
CTNNB1Catenin beta 1. (781 aa)
H3B5P8_LATCHZNRF_3_ecto domain-containing protein. (60 aa)
ZNRF3Zinc and ring finger 3. (698 aa)
KREMEN1Kringle containing transmembrane protein 1. (249 aa)
AMER1APC membrane recruitment protein 1. (900 aa)
AMER2APC membrane recruitment protein 2. (641 aa)
TLE4Uncharacterized protein. (734 aa)
LOC102356742Sizzled. (295 aa)
IGFBP6Insulin like growth factor binding protein 6. (271 aa)
LOC102355199Uncharacterized protein. (301 aa)
LOC102354118Dickkopf_N domain-containing protein. (243 aa)
SCYL2SCY1 like pseudokinase 2. (939 aa)
AXIN2Axin 2. (841 aa)
H3BE69_LATCHPID domain-containing protein. (136 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (466 aa)
G3BP1G3BP stress granule assembly factor 1. (481 aa)
FRMD8FERM domain containing 8. (465 aa)
H3BFW7_LATCHBHLH domain-containing protein. (161 aa)
H3BFZ2_LATCHBHLH domain-containing protein. (165 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
MDKMidkine. (141 aa)
SOX9SRY-box transcription factor 9. (475 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (815 aa)
DDIT3DNA damage inducible transcript 3. (256 aa)
GLI1GLI family zinc finger 1. (1380 aa)
NPHP4Nephrocystin 4. (1207 aa)
TMEM88BUncharacterized protein. (143 aa)
DRAXINDorsal inhibitory axon guidance protein. (347 aa)
TLE1Uncharacterized protein. (655 aa)
LOC102356000Uncharacterized protein. (211 aa)
OTUD5OTU deubiquitinase 5. (534 aa)
LOC102359396Uncharacterized protein. (483 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1222 aa)
LOC102346204Protein kinase domain-containing protein. (227 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (530 aa)
STK4Serine/threonine kinase 4. (488 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (387 aa)
LZTS2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (678 aa)
MCCMCC regulator of WNT signaling pathway. (765 aa)
GLI3GLI family zinc finger 3. (1456 aa)
SOX10SRY-box transcription factor 10. (451 aa)
FRZBFrizzled related protein. (318 aa)
TPBGTrophoblast glycoprotein. (386 aa)
LOC102358266Dickkopf WNT signaling pathway inhibitor 1b. (261 aa)
SFRP4Secreted frizzled related protein 4. (198 aa)
APCAPC regulator of WNT signaling pathway. (2802 aa)
LOC102365523Uncharacterized protein; Belongs to the peptidase C19 family. (930 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (212 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ANKRD6Ankyrin repeat domain 6. (791 aa)
H3AJR0_LATCHSRY-box transcription factor 13. (427 aa)
LATS2Large tumor suppressor kinase 2. (1108 aa)
NPHP3Nephronophthisis 3. (1314 aa)
SOX13Uncharacterized protein. (195 aa)
H3AMA1_LATCHUncharacterized protein. (612 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (959 aa)
SFRP1-2FZ domain-containing protein. (203 aa)
H3ANG8_LATCHUncharacterized protein. (321 aa)
LATS1Large tumor suppressor kinase 1. (1140 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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