STRINGSTRING
VWC2 VWC2 H2ZRM4_LATCH H2ZRM4_LATCH LOC102350617 LOC102350617 CHRD CHRD H2ZTV2_LATCH H2ZTV2_LATCH LOC102363464 LOC102363464 LOC102354291 LOC102354291 VEPH1-2 VEPH1-2 DLX1 DLX1 CER1 CER1 CILP2 CILP2 TNFAIP6 TNFAIP6 WFIKKN2 WFIKKN2 LOC102358266 LOC102358266 SPART SPART SMAD6 SMAD6 SNX25 SNX25 ZNF451 ZNF451 SMAD7 SMAD7 DACT2 DACT2 GREM1 GREM1 LOC102352233 LOC102352233 SFRP2 SFRP2 CCN3 CCN3 BAMBI BAMBI LINGO3 LINGO3 NRROS NRROS NOG NOG SIRT1 SIRT1 STRAP STRAP TWSG1 TWSG1 SKOR2 SKOR2 SLC2A10 SLC2A10 FBN1 FBN1 ADAMTSL2 ADAMTSL2 FAM89B FAM89B ADAM17 ADAM17 FSTL3 FSTL3 EMILIN1 EMILIN1 IL17RD IL17RD ACVR1 ACVR1 LEMD3 LEMD3 CHRDL1 CHRDL1 NBL1 NBL1 ZBTB7A ZBTB7A SOST SOST LDLRAD4 LDLRAD4 HTRA3 HTRA3 TBX20 TBX20 SORL1 SORL1 SOSTDC1 SOSTDC1 CTDSPL2 CTDSPL2 PPARA PPARA LOC102357384 LOC102357384 SPRED1 SPRED1 CHST11 CHST11 H3AVW8_LATCH H3AVW8_LATCH HJV HJV LOC102348675 LOC102348675 FST FST CAV2 CAV2 MAGI2 MAGI2 GREM2 GREM2 VEPH1 VEPH1 SKI SKI PBLD PBLD BBIP1 BBIP1 TP53 TP53 SKOR1 SKOR1 WFIKKN1 WFIKKN1 SMURF2 SMURF2 SKIL SKIL H3B4C9_LATCH H3B4C9_LATCH SPRY1 SPRY1 DAND5 DAND5 VWC2L VWC2L LEMD2 LEMD2 CILP CILP H3BB14_LATCH H3BB14_LATCH BCL9L BCL9L CRIM1 CRIM1 PMEPA1 PMEPA1 HSPA5 HSPA5 CAV3 CAV3 SPRED3 SPRED3 PPM1A PPM1A ARID4A ARID4A PRDM16-2 PRDM16-2 WNT1 WNT1 PRDM16 PRDM16 RBPMS2 RBPMS2 BMPER BMPER M3XLP3_LATCH M3XLP3_LATCH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VWC2Von Willebrand factor C domain containing 2. (270 aa)
H2ZRM4_LATCHUncharacterized protein. (379 aa)
LOC102350617Uncharacterized protein. (222 aa)
CHRDChordin; Belongs to the chordin family. (948 aa)
H2ZTV2_LATCHUncharacterized protein. (383 aa)
LOC102363464Si:ch211-267e7.3. (924 aa)
LOC102354291Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (169 aa)
VEPH1-2Uncharacterized protein. (196 aa)
DLX1Distal-less homeobox 1. (253 aa)
CER1CTCK domain-containing protein. (257 aa)
CILP2Cartilage intermediate layer protein 2. (1075 aa)
TNFAIP6TNF alpha induced protein 6. (279 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (575 aa)
LOC102358266Dickkopf WNT signaling pathway inhibitor 1b. (261 aa)
SPARTSpartin. (664 aa)
SMAD6Mothers against decapentaplegic homolog. (485 aa)
SNX25Sorting nexin 25. (620 aa)
ZNF451Zinc finger protein 451. (1068 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
DACT2Dishevelled-binding antagonist of beta-catenin 2. (770 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (189 aa)
LOC102352233Uncharacterized protein. (511 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
CCN3Cellular communication network factor 3. (345 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
LINGO3Leucine rich repeat and Ig domain containing 3a. (624 aa)
NRROSNegative regulator of reactive oxygen species. (691 aa)
NOGNoggin; Belongs to the noggin family. (223 aa)
SIRT1Sirtuin 1. (729 aa)
STRAPSerine/threonine kinase receptor associated protein. (329 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (220 aa)
SKOR2SKI family transcriptional corepressor 2. (721 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (535 aa)
FBN1Fibrillin 1. (2872 aa)
ADAMTSL2ADAMTS like 2. (952 aa)
FAM89BFamily with sequence similarity 89 member B. (179 aa)
ADAM17ADAM metallopeptidase domain 17. (827 aa)
FSTL3Follistatin like 3. (248 aa)
EMILIN1Elastin microfibril interfacer 1. (1047 aa)
IL17RDInterleukin 17 receptor D. (698 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
LEMD3LEM domain containing 3. (705 aa)
CHRDL1Chordin like 1. (458 aa)
NBL1NBL1, DAN family BMP antagonist. (184 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (518 aa)
SOSTSclerostin. (210 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (310 aa)
HTRA3HtrA serine peptidase 3. (460 aa)
TBX20T-box transcription factor 20. (441 aa)
SORL1Sortilin-related receptor, L(DLR class) A repeats containing. (1410 aa)
SOSTDC1Sclerostin domain containing 1. (213 aa)
CTDSPL2FCP1 homology domain-containing protein. (2335 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
LOC102357384Noggin; Belongs to the noggin family. (216 aa)
SPRED1Sprouty related EVH1 domain containing 1. (446 aa)
CHST11Carbohydrate sulfotransferase. (298 aa)
H3AVW8_LATCHMothers against decapentaplegic homolog. (369 aa)
HJVHemojuvelin BMP co-receptor. (404 aa)
LOC102348675Nodal modulator. (1131 aa)
FSTFollistatin. (319 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (163 aa)
MAGI2Uncharacterized protein. (397 aa)
GREM2Gremlin 2, DAN family BMP antagonist. (167 aa)
VEPH1Ventricular zone expressed PH domain containing 1. (528 aa)
SKISKI proto-oncogene. (702 aa)
PBLDPhenazine biosynthesis like protein domain containing. (288 aa)
BBIP1Uncharacterized protein. (499 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
SKOR1SKI family transcriptional corepressor 1. (787 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (556 aa)
SMURF2E3 ubiquitin-protein ligase. (754 aa)
SKILSKI like proto-oncogene. (691 aa)
H3B4C9_LATCHPDZ domain-containing protein. (105 aa)
SPRY1Sprouty RTK signaling antagonist 1. (320 aa)
DAND5CTCK domain-containing protein. (247 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (176 aa)
LEMD2LEM domain containing 2. (416 aa)
CILPCartilage intermediate layer protein. (1183 aa)
H3BB14_LATCHUncharacterized protein. (123 aa)
BCL9LBCL9 like. (1514 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (881 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (284 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
SPRED3Sprouty related EVH1 domain containing 3. (453 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (383 aa)
ARID4AAT-rich interaction domain 4A. (1297 aa)
PRDM16-2Si:ch211-263k4.2. (114 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
PRDM16PR/SET domain 16. (1135 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (227 aa)
BMPERBMP binding endothelial regulator. (682 aa)
M3XLP3_LATCHUncharacterized protein. (408 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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