STRINGSTRING
LOC102351466 LOC102351466 LOC102355203 LOC102355203 H2ZU49_LATCH H2ZU49_LATCH TACR3 TACR3 ADRA1A ADRA1A CTDP1 CTDP1 GJA5 GJA5 TNNI3 TNNI3 PARP1 PARP1 CASQ1 CASQ1 TNNT1 TNNT1 LOC102365269 LOC102365269 PARP2 PARP2 H3A551_LATCH H3A551_LATCH HAND2 HAND2 MYL5 MYL5 MLIP MLIP GLRX3 GLRX3 TACR1 TACR1 FBXO32 FBXO32 ADRA2C ADRA2C JUP JUP TOMM70 TOMM70 SMAD7 SMAD7 ERRFI1 ERRFI1 GSK3A GSK3A RANGRF RANGRF CASQ2 CASQ2 IGFBP5 IGFBP5 GPER1 GPER1 H3AF01_LATCH H3AF01_LATCH ADRA2B ADRA2B H3AHJ4_LATCH H3AHJ4_LATCH SMAD4 SMAD4 KCNQ1 KCNQ1 IL6ST IL6ST LOC102356355 LOC102356355 AKAP6 AKAP6 SCN4A SCN4A ATP2A1 ATP2A1 FPGT FPGT UCN UCN LOC102353564 LOC102353564 PDE9A PDE9A DOCK4 DOCK4 TACR2 TACR2 LOC102347966 LOC102347966 TNNT3 TNNT3 TNNI1 TNNI1 TNNT2 TNNT2 GSK3B GSK3B TIFAB TIFAB ATP2B4 ATP2B4 CAV1 CAV1 ANKRD28 ANKRD28 ANKRD66 ANKRD66 SETD3 SETD3 H3B053_LATCH H3B053_LATCH H3B102_LATCH H3B102_LATCH H3B155_LATCH H3B155_LATCH LOC102345989 LOC102345989 ANKRD44 ANKRD44 MYOCD MYOCD ROCK1 ROCK1 SRF SRF CMYA5 CMYA5 LOC102350553 LOC102350553 LOC102360622 LOC102360622 MYOG MYOG NKX2-5 NKX2-5 TBXA2R TBXA2R CHRM2 CHRM2 TRIM63 TRIM63 ABCC8 ABCC8 RNF207 RNF207 EDN1 EDN1 KBTBD13 KBTBD13 ANXA6 ANXA6 ZC3H12A ZC3H12A LMCD1 LMCD1 CAV3 CAV3 GTF2IRD1 GTF2IRD1 P2RX1 P2RX1 TNNC1 TNNC1 H3BH85_LATCH H3BH85_LATCH LOC102352170 LOC102352170 ANKRD52 ANKRD52 LOC102358988 LOC102358988 ATP2A2 ATP2A2 P2RX4 P2RX4 G6PD G6PD TMEM38B TMEM38B TNFRSF1B TNFRSF1B PKP2 PKP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102351466Uncharacterized protein. (201 aa)
LOC102355203Na_H_Exchanger domain-containing protein. (161 aa)
H2ZU49_LATCHCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1044 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (326 aa)
ADRA1AAdrenoceptor alpha 1A. (459 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (846 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (371 aa)
TNNI3Uncharacterized protein. (240 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (466 aa)
TNNT1Troponin T1, slow skeletal type. (253 aa)
LOC102365269G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PARP2Poly [ADP-ribose] polymerase. (502 aa)
H3A551_LATCHPhosphodiesterase. (437 aa)
HAND2Heart and neural crest derivatives expressed 2. (210 aa)
MYL5Myosin light chain 5. (188 aa)
MLIPUncharacterized protein. (1070 aa)
GLRX3Glutaredoxin 3. (332 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (415 aa)
FBXO32F-box protein 32. (353 aa)
ADRA2CAdrenoceptor alpha 2C. (434 aa)
JUPJunction plakoglobin. (694 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (601 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (468 aa)
GSK3AGlycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (463 aa)
RANGRFUncharacterized protein. (203 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (412 aa)
IGFBP5Insulin like growth factor binding protein 5. (279 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
H3AF01_LATCHUncharacterized protein. (658 aa)
ADRA2BAdrenoceptor alpha 2B. (452 aa)
H3AHJ4_LATCHIon_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
SMAD4MH2 domain-containing protein. (412 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
IL6STInterleukin 6 signal transducer. (922 aa)
LOC102356355TNFR-Cys domain-containing protein. (163 aa)
AKAP6Uncharacterized protein. (901 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
ATP2A1ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1013 aa)
FPGTTNNI3 interacting kinase. (938 aa)
UCNUrocortin. (167 aa)
LOC102353564Uncharacterized protein. (161 aa)
PDE9APhosphodiesterase. (519 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1826 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (371 aa)
LOC102347966SCP domain-containing protein; Belongs to the CRISP family. (163 aa)
TNNT3Troponin T3, fast skeletal type. (227 aa)
TNNI1Troponin I1, slow skeletal type. (171 aa)
TNNT2Troponin T2, cardiac type. (286 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
TIFABTIFA inhibitor. (149 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1233 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
ANKRD28Ankyrin repeat domain 28. (934 aa)
ANKRD66Ankyrin repeat domain 66. (191 aa)
SETD3Protein-histidine N-methyltransferase. (297 aa)
H3B053_LATCHProtein-histidine N-methyltransferase. (302 aa)
H3B102_LATCHCation_ATPase_C domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (176 aa)
H3B155_LATCHANK_REP_REGION domain-containing protein. (374 aa)
LOC102345989Uncharacterized protein. (92 aa)
ANKRD44ANK_REP_REGION domain-containing protein. (619 aa)
MYOCDMyocardin. (963 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1350 aa)
SRFSerum response factor. (520 aa)
CMYA5Uncharacterized protein. (1165 aa)
LOC102350553Uncharacterized protein. (232 aa)
LOC102360622Phosphodiesterase. (504 aa)
MYOGMyogenin. (242 aa)
NKX2-5NK2 homeobox 5. (296 aa)
TBXA2RThromboxane A2 receptor. (351 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (475 aa)
TRIM63Tripartite motif containing 63. (354 aa)
ABCC8ATP binding cassette subfamily C member 8. (1591 aa)
RNF207Ring finger protein 207. (648 aa)
EDN1Endothelin 1. (216 aa)
KBTBD13Kelch repeat and BTB domain containing 13. (445 aa)
ANXA6Annexin. (662 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (600 aa)
LMCD1LIM and cysteine rich domains 1. (375 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
GTF2IRD1GTF2I repeat domain containing 1. (956 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (403 aa)
TNNC1Troponin C type 1a (slow). (164 aa)
H3BH85_LATCHUncharacterized protein. (164 aa)
LOC102352170Uncharacterized protein. (163 aa)
ANKRD52Ankyrin repeat domain 52. (1049 aa)
LOC102358988Mothers against decapentaplegic homolog. (614 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1007 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
TMEM38BTransmembrane protein 38B. (302 aa)
TNFRSF1BTNF receptor superfamily member 1B. (465 aa)
PKP2Uncharacterized protein. (815 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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