STRINGSTRING
EFNA5 EFNA5 UQCC2 UQCC2 ABCC8 ABCC8 CAPN10 CAPN10 LRRC8A LRRC8A SYTL4 SYTL4 INHBB INHBB KLF7 KLF7 GHRL GHRL STXBP4 STXBP4 TRPM2 TRPM2 SYT9 SYT9 NDUFAF2 NDUFAF2 TM7SF3 TM7SF3 CRHBP CRHBP SLC8B1 SLC8B1 LOC102346472 LOC102346472 NR0B2 NR0B2 AACS AACS MPC2 MPC2 AIMP1 AIMP1 ADCY8 ADCY8 FAM3D FAM3D LEP LEP BAD BAD UCN UCN NR1D1 NR1D1 TRH TRH SYT7 SYT7 SELENOT SELENOT MIDN MIDN H3AIM8_LATCH H3AIM8_LATCH ACVR1C ACVR1C IL6 IL6 TNFSF11 TNFSF11 SIRT6 SIRT6 FGB FGB H3AEV1_LATCH H3AEV1_LATCH GPER1 GPER1 CCN3 CCN3 PICK1 PICK1 PLA2G6 PLA2G6 FGG FGG PIM2 PIM2 ARNTL ARNTL RFX6 RFX6 FFAR1 FFAR1 PAX8 PAX8 HADH HADH HTR2C HTR2C CRH CRH ACSL4 ACSL4 CFTR CFTR BLK BLK LOC102351466 LOC102351466 H2ZS97_LATCH H2ZS97_LATCH LOC102358678 LOC102358678 PIM3 PIM3 GPLD1 GPLD1 LOC102367457 LOC102367457 H2ZYB6_LATCH H2ZYB6_LATCH EIPR1 EIPR1 C1QTNF12 C1QTNF12 LRP5 LRP5 DRD2 DRD2 SIRT4 SIRT4 PSMD9 PSMD9 NR1H4 NR1H4 BIRC5 BIRC5 ADCYAP1 ADCYAP1 KCNJ11 KCNJ11 C2CD2L C2CD2L PDX1 PDX1 KCNB1 KCNB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFNA5Ephrin A5; Belongs to the ephrin family. (185 aa)
UQCC2Ubiquinol-cytochrome c reductase complex assembly factor 2. (138 aa)
ABCC8ATP binding cassette subfamily C member 8. (1591 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (671 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (809 aa)
SYTL4Synaptotagmin like 4. (641 aa)
INHBBInhibin subunit beta B. (393 aa)
KLF7Kruppel like factor 7. (294 aa)
GHRLMotilin_assoc domain-containing protein. (110 aa)
STXBP4Syntaxin binding protein 4. (703 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1473 aa)
SYT9Synaptotagmin 9. (454 aa)
NDUFAF2NADH:ubiquinone oxidoreductase complex assembly factor 2. (167 aa)
TM7SF3Transmembrane 7 superfamily member 3. (575 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (323 aa)
SLC8B1Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (539 aa)
LOC102346472Uncharacterized protein. (168 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (260 aa)
AACSAcetoacetyl-CoA synthetase. (670 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (131 aa)
AIMP1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (311 aa)
ADCY8AC_N domain-containing protein. (266 aa)
FAM3DFamily with sequence similarity 3 member D. (228 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
BADUncharacterized protein. (175 aa)
UCNUrocortin. (167 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (614 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (262 aa)
SYT7Synaptotagmin 7. (286 aa)
SELENOTSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (137 aa)
MIDNMidnolin. (524 aa)
H3AIM8_LATCHUncharacterized protein. (206 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
IL6Uncharacterized protein. (149 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (169 aa)
SIRT6Sirtuin 6. (375 aa)
FGBFibrinogen beta chain. (454 aa)
H3AEV1_LATCHTNF_2 domain-containing protein. (230 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
CCN3Cellular communication network factor 3. (345 aa)
PICK1Protein interacting with PRKCA 1. (409 aa)
PLA2G6Phospholipase A2 group VI. (815 aa)
FGGFibrinogen gamma chain. (376 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (324 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (635 aa)
RFX6Regulatory factor X6. (929 aa)
FFAR1Free fatty acid receptor 1. (279 aa)
PAX8Paired box 8. (458 aa)
HADHHydroxyacyl-CoA dehydrogenase. (309 aa)
HTR2C5-hydroxytryptamine receptor 2C; Belongs to the G-protein coupled receptor 1 family. (342 aa)
CRHCorticotropin releasing hormone. (166 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (713 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1491 aa)
BLKTyrosine-protein kinase. (447 aa)
LOC102351466Uncharacterized protein. (201 aa)
H2ZS97_LATCHTNF_2 domain-containing protein. (143 aa)
LOC102358678G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (304 aa)
PIM3Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (324 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (835 aa)
LOC102367457G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (312 aa)
H2ZYB6_LATCHUncharacterized protein. (324 aa)
EIPR1EARP complex and GARP complex interacting protein 1. (387 aa)
C1QTNF12C1q and TNF related 12. (265 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1598 aa)
DRD2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
SIRT4NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (315 aa)
PSMD9Proteasome 26S subunit, non-ATPase 9. (210 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (456 aa)
BIRC5Baculoviral IAP repeat containing 5. (139 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (199 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (392 aa)
C2CD2LC2CD2 like. (701 aa)
PDX1Pancreatic and duodenal homeobox 1. (257 aa)
KCNB1Potassium voltage-gated channel, Shab-related subfamily, member 1; Belongs to the potassium channel family. (677 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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