STRINGSTRING
PSEN1 PSEN1 TM9SF4 TM9SF4 C2CD5 C2CD5 LOC102345119 LOC102345119 PRR5L PRR5L LOC102367486 LOC102367486 SMO SMO RAB29 RAB29 H2ZZY5_LATCH H2ZZY5_LATCH CEP290 CEP290 UBE2L6 UBE2L6 MIEF1 MIEF1 PRKAA1 PRKAA1 GLI3 GLI3 H3A6W7_LATCH H3A6W7_LATCH JUP JUP CHP1 CHP1 XPO4 XPO4 PDZK1 PDZK1 GSK3A GSK3A SIRT6 SIRT6 RIPOR1 RIPOR1 RUFY3 RUFY3 ITGB1BP1 ITGB1BP1 CDK5 CDK5 MIEF2 MIEF2 ZFAND1 ZFAND1 HPS4 HPS4 DMAP1 DMAP1 B3GAT3 B3GAT3 MFF MFF ICE1 ICE1 MYO1C MYO1C LEP LEP SORL1 SORL1 CTDSPL2 CTDSPL2 GSK3B GSK3B BAG3 BAG3 OAZ2 OAZ2 FBXW9 FBXW9 UBR5 UBR5 PDCD10 PDCD10 PDCD5 PDCD5 ECT2 ECT2 CEP131 CEP131 TENM4 TENM4 GAS6 GAS6 ZPR1 ZPR1 EFCAB7 EFCAB7 IPO5 IPO5 TPR TPR EDEM1 EDEM1 BCAS3 BCAS3 CIB1 CIB1 KCNB1 KCNB1 H3BBT9_LATCH H3BBT9_LATCH ZC3H12A ZC3H12A EDEM2 EDEM2 TGFB1 TGFB1 PPM1A PPM1A RAPGEF3 RAPGEF3 OAZ1 OAZ1 FBXW7 FBXW7 SAR1B SAR1B CHP2 CHP2 PCM1 PCM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
TM9SF4Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (395 aa)
C2CD5C2 calcium dependent domain containing 5. (581 aa)
LOC102345119Uncharacterized protein. (326 aa)
PRR5LProline rich 5 like. (365 aa)
LOC102367486Uncharacterized protein. (419 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (820 aa)
RAB29RAB29, member RAS oncogene family. (206 aa)
H2ZZY5_LATCHUncharacterized protein. (548 aa)
CEP290Centrosomal protein 290. (2474 aa)
UBE2L6UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (144 aa)
MIEF1Mitochondrial elongation factor 1. (548 aa)
PRKAA1Non-specific serine/threonine protein kinase. (552 aa)
GLI3GLI family zinc finger 3. (1456 aa)
H3A6W7_LATCHC2 domain-containing protein. (310 aa)
JUPJunction plakoglobin. (694 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
XPO4Exportin 4. (1132 aa)
PDZK1PDZ domain containing 1. (523 aa)
GSK3AGlycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (463 aa)
SIRT6Sirtuin 6. (375 aa)
RIPOR1RHO family interacting cell polarization regulator 1. (1071 aa)
RUFY3RUN and FYVE domain containing 3. (715 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
CDK5Cyclin dependent kinase 5. (290 aa)
MIEF2Mitochondrial elongation factor 2. (464 aa)
ZFAND1Zinc finger AN1-type containing 1. (268 aa)
HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (720 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (402 aa)
B3GAT3Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (329 aa)
MFFMitochondrial fission factor. (345 aa)
ICE1Uncharacterized protein. (520 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1036 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
SORL1Sortilin-related receptor, L(DLR class) A repeats containing. (1410 aa)
CTDSPL2FCP1 homology domain-containing protein. (2335 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
BAG3BCL2 associated athanogene 3. (561 aa)
OAZ2Uncharacterized protein. (187 aa)
FBXW9F-box and WD repeat domain containing 9. (465 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2787 aa)
PDCD10Programmed cell death 10. (210 aa)
PDCD5Programmed cell death 5. (128 aa)
ECT2Epithelial cell transforming 2. (919 aa)
CEP131Centrosomal protein 131. (1092 aa)
TENM4Teneurin transmembrane protein 4. (1073 aa)
GAS6Uncharacterized protein. (681 aa)
ZPR1ZPR1 zinc finger. (470 aa)
EFCAB7EF-hand calcium binding domain 7. (631 aa)
IPO5Importin 5. (1107 aa)
TPRTranslocated promoter region, nuclear basket protein. (2360 aa)
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (654 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (806 aa)
CIB1Calcium and integrin binding 1. (190 aa)
KCNB1Potassium voltage-gated channel, Shab-related subfamily, member 1; Belongs to the potassium channel family. (677 aa)
H3BBT9_LATCHUncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (199 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (600 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (576 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (383 aa)
RAPGEF3Ras-GEF domain-containing protein. (459 aa)
OAZ1Uncharacterized protein. (174 aa)
FBXW7F-box and WD repeat domain containing 7. (713 aa)
SAR1BSecretion associated, Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
CHP2Calcineurin like EF-hand protein 2. (194 aa)
PCM1Pericentriolar material 1. (2154 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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