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TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa) | ||||
H2ZV40_LATCH | Protein kinase domain-containing protein. (266 aa) | ||||
H2ZS97_LATCH | TNF_2 domain-containing protein. (143 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (667 aa) | ||||
DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (778 aa) | ||||
CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (959 aa) | ||||
FADD | Fas associated via death domain. (193 aa) | ||||
ALKBH7 | AlkB homolog 7. (231 aa) | ||||
H3AEV1_LATCH | TNF_2 domain-containing protein. (230 aa) | ||||
BAX | Uncharacterized protein. (223 aa) | ||||
FAS | Uncharacterized protein. (330 aa) | ||||
MLKL | Protein kinase domain-containing protein. (520 aa) | ||||
IPMK | Kinase; Belongs to the inositol phosphokinase (IPK) family. (357 aa) | ||||
ITPK1 | Inositol-tetrakisphosphate 1-kinase. (406 aa) | ||||
LOC102366649 | Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family. (357 aa) | ||||
PGAM5 | PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (293 aa) | ||||
IRF3 | Interferon regulatory factor 3. (481 aa) | ||||
FASLG | Fas ligand. (261 aa) | ||||
LOC102360171 | Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (426 aa) | ||||
TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (766 aa) |