STRINGSTRING
RARG RARG CER1 CER1 BNC2 BNC2 TGFBR2 TGFBR2 RARA RARA EVC EVC RARB RARB ZMPSTE24 ZMPSTE24 ECM1 ECM1 LEPR LEPR LOC102348760 LOC102348760 LOC106703556 LOC106703556 THBS3 THBS3 LOC102364365 LOC102364365 LEP LEP IFT80 IFT80 MMP13 MMP13 OSTN OSTN ANXA6 ANXA6 BNC2-2 BNC2-2 DDR2 DDR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RARGRetinoic acid receptor gamma. (389 aa)
CER1CTCK domain-containing protein. (257 aa)
BNC2Basonuclin 2. (880 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
RARARetinoic acid receptor alpha. (505 aa)
EVCEvC ciliary complex subunit 1. (814 aa)
RARBNR LBD domain-containing protein. (299 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (453 aa)
ECM1Uncharacterized protein. (366 aa)
LEPRLeptin receptor. (1149 aa)
LOC102348760Uncharacterized protein. (782 aa)
LOC106703556Natriuretic peptide A-like. (129 aa)
THBS3Thrombospondin 3. (930 aa)
LOC102364365Natriuretic peptide A-like. (130 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
IFT80Intraflagellar transport 80. (780 aa)
MMP13Matrix metallopeptidase 13. (467 aa)
OSTNOsteocrin. (136 aa)
ANXA6Annexin. (662 aa)
BNC2-2Uncharacterized protein. (124 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (838 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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