(49 nodes) Postsynapse organization network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102359008	Uncharacterized protein. (1519 aa)
	SHISA7	Shisa family member 7. (469 aa)
	LOC102356325	Eph LBD domain-containing protein. (260 aa)
	FNTA	Farnesyltransferase, CAAX box, alpha. (363 aa)
	EPHB4	EPH receptor B4. (976 aa)
	GLRB	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (498 aa)
	SHANK1	SH3 and multiple ankyrin repeat domains 1. (1849 aa)
	CNKSR2	Connector enhancer of kinase suppressor of Ras 2. (805 aa)
	ITPKA	Kinase; Belongs to the inositol phosphokinase (IPK) family. (308 aa)
	COLQ	Collagen like tail subunit of asymmetric acetylcholinesterase. (452 aa)
	NLGN1	Neuroligin 1. (635 aa)
	ITGA3	Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1012 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1187 aa)
	LOC102349972	Uncharacterized protein. (246 aa)
	SHANK2	SH3 and multiple ankyrin repeat domains 2. (1161 aa)
	EPHA10	Uncharacterized protein. (732 aa)
	LOC102354107	Neuroligin 4 X-linked a. (835 aa)
	EPHB6	EPH receptor B6. (974 aa)
	GDNF	Glial cell derived neurotrophic factor. (222 aa)
	LRRTM4	Leucine rich repeat transmembrane neuronal 4. (519 aa)
	PICK1	Protein interacting with PRKCA 1. (409 aa)
	ADAM10	ADAM metallopeptidase domain 10b. (679 aa)
	LOC102363797	Uncharacterized protein. (603 aa)
	NLGN2	Neuroligin 2. (802 aa)
	NLGN3	Neuroligin 3. (855 aa)
	GPHN	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (777 aa)
	PRMT3	Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (508 aa)
	HOMER1	Homer scaffold protein 1. (367 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (828 aa)
	EPHB3	EPH receptor B3. (996 aa)
	DBN1	Drebrin 1. (684 aa)
	TMEM108	Transmembrane protein 108. (355 aa)
	NOS1AP	Uncharacterized protein. (192 aa)
	ZDHHC12	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (268 aa)
	TANC1	Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (1815 aa)
	CDC42	Cell division cycle 42. (156 aa)
	EPHB1	EPH receptor B1. (509 aa)
	WASF2	WASP family member 2. (503 aa)
	NEFL	Neurofilament light; Belongs to the intermediate filament family. (555 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (928 aa)
	DBNL	Drebrin like. (512 aa)
	DOCK10	Dedicator of cytokinesis 10; Belongs to the DOCK family. (2199 aa)
	NTNG2	Netrin G2. (531 aa)
	LOC102350663	Si:ch211-218g4.2. (1040 aa)
	LGMN	Legumain. (436 aa)
	RELN	Reelin. (3462 aa)
	DLG3	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (901 aa)
	LOC102347127	ADF-H domain-containing protein. (892 aa)
	ARHGAP39	Rho GTPase activating protein 39. (1077 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP39	CDC42	ENSLACP00000023474	ENSLACP00000018010	Rho GTPase activating protein 39.	Cell division cycle 42.	0.520
CDC42	ARHGAP39	ENSLACP00000018010	ENSLACP00000023474	Cell division cycle 42.	Rho GTPase activating protein 39.	0.520
CDC42	DOCK10	ENSLACP00000018010	ENSLACP00000019258	Cell division cycle 42.	Dedicator of cytokinesis 10; Belongs to the DOCK family.	0.953
CDC42	EPHB4	ENSLACP00000018010	ENSLACP00000003330	Cell division cycle 42.	EPH receptor B4.	0.401
CDC42	LOC102350663	ENSLACP00000018010	ENSLACP00000021380	Cell division cycle 42.	Si:ch211-218g4.2.	0.520
CDC42	LOC102363797	ENSLACP00000018010	ENSLACP00000008575	Cell division cycle 42.	Uncharacterized protein.	0.463
CDC42	SHANK1	ENSLACP00000018010	ENSLACP00000003891	Cell division cycle 42.	SH3 and multiple ankyrin repeat domains 1.	0.463
CDC42	SHANK3	ENSLACP00000018010	ENSLACP00000004784	Cell division cycle 42.	SH3 and multiple ankyrin repeat domains 3.	0.480
CDC42	WASF2	ENSLACP00000018010	ENSLACP00000018313	Cell division cycle 42.	WASP family member 2.	0.771
DLG1	LOC102354107	ENSLACP00000018954	ENSLACP00000006303	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Neuroligin 4 X-linked a.	0.433
DLG1	LOC102363797	ENSLACP00000018954	ENSLACP00000008575	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Uncharacterized protein.	0.645
DLG1	NLGN1	ENSLACP00000018954	ENSLACP00000004380	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Neuroligin 1.	0.433
DLG1	NLGN2	ENSLACP00000018954	ENSLACP00000010962	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Neuroligin 2.	0.433
DLG1	NLGN3	ENSLACP00000018954	ENSLACP00000012052	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Neuroligin 3.	0.433
DLG1	SHANK1	ENSLACP00000018954	ENSLACP00000003891	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 1.	0.645
DLG1	SHANK2	ENSLACP00000018954	ENSLACP00000005361	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 2.	0.553
DLG1	SHANK3	ENSLACP00000018954	ENSLACP00000004784	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 3.	0.670
DLG3	LOC102354107	ENSLACP00000022891	ENSLACP00000006303	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Neuroligin 4 X-linked a.	0.433
DLG3	LOC102363797	ENSLACP00000022891	ENSLACP00000008575	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Uncharacterized protein.	0.645
DLG3	NLGN1	ENSLACP00000022891	ENSLACP00000004380	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Neuroligin 1.	0.433