(9 nodes) Regulation of receptor binding network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C1QTNF9	C1q domain-containing protein. (198 aa)
	GREM2	Gremlin 2, DAN family BMP antagonist. (167 aa)
	PHLDA2	Pleckstrin homology like domain family A member 2. (137 aa)
	LOC102346019	C1q domain-containing protein. (226 aa)
	LOC102367479	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (992 aa)
	MMP9	Matrix metallopeptidase 9. (682 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9. (672 aa)
	IL10	Interleukin 10. (185 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (259 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	IL10	ENSLACP00000000452	ENSLACP00000005382	Adiponectin, C1Q and collagen domain containing.	Interleukin 10.	0.544
ADIPOQ	LOC102346019	ENSLACP00000000452	ENSLACP00000019134	Adiponectin, C1Q and collagen domain containing.	C1q domain-containing protein.	0.904
IL10	ADIPOQ	ENSLACP00000005382	ENSLACP00000000452	Interleukin 10.	Adiponectin, C1Q and collagen domain containing.	0.544
IL10	LOC102346019	ENSLACP00000005382	ENSLACP00000019134	Interleukin 10.	C1q domain-containing protein.	0.470
IL10	MMP9	ENSLACP00000005382	ENSLACP00000014693	Interleukin 10.	Matrix metallopeptidase 9.	0.705
LOC102346019	ADIPOQ	ENSLACP00000019134	ENSLACP00000000452	C1q domain-containing protein.	Adiponectin, C1Q and collagen domain containing.	0.904
LOC102346019	IL10	ENSLACP00000019134	ENSLACP00000005382	C1q domain-containing protein.	Interleukin 10.	0.470
MMP9	IL10	ENSLACP00000014693	ENSLACP00000005382	Matrix metallopeptidase 9.	Interleukin 10.	0.705