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VPS13D | Vacuolar protein sorting 13 homolog D. (4423 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa) | ||||
RNF41 | Ring finger protein 41. (319 aa) | ||||
PINK1 | PTEN induced kinase 1. (467 aa) | ||||
TIGAR | TP53 induced glycolysis regulatory phosphatase. (212 aa) | ||||
AMBRA1 | Autophagy and beclin 1 regulator 1. (1195 aa) |