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NME5 NME5 H2ZYB6_LATCH H2ZYB6_LATCH ATF4 ATF4 IL10 IL10 GPR37 GPR37 HSPB1 HSPB1 LOC102348760 LOC102348760 SIRT1 SIRT1 NFE2L2 NFE2L2 NCOA7 NCOA7 SLC7A11 SLC7A11 BAG5 BAG5 GFER GFER TSC1 TSC1 LRRK2 LRRK2 DDR2 DDR2 OXR1 OXR1 TRAP1 TRAP1 FBXO7 FBXO7 MET MET GPR37L1 GPR37L1 RACK1 RACK1 CTNNB1 CTNNB1 SOD2 SOD2 PINK1 PINK1 WNT1 WNT1 HGF HGF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NME5NME/NM23 family member 5; Belongs to the NDK family. (270 aa)
H2ZYB6_LATCHUncharacterized protein. (324 aa)
ATF4Activating transcription factor 4. (374 aa)
IL10Interleukin 10. (185 aa)
GPR37G protein-coupled receptor 37. (380 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (219 aa)
LOC102348760Uncharacterized protein. (782 aa)
SIRT1Sirtuin 1. (729 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (590 aa)
NCOA7Nuclear receptor coactivator 7. (862 aa)
SLC7A11Solute carrier family 7 member 11. (501 aa)
BAG5BCL2 associated athanogene 5. (460 aa)
GFERSulfhydryl oxidase. (193 aa)
TSC1TSC complex subunit 1. (1217 aa)
LRRK2Leucine rich repeat kinase 2. (2508 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (838 aa)
OXR1Oxidation resistance 1. (840 aa)
TRAP1TNF receptor associated protein 1. (718 aa)
FBXO7F-box protein 7. (482 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1385 aa)
GPR37L1G protein-coupled receptor 37 like 1. (454 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
CTNNB1Catenin beta 1. (781 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (223 aa)
PINK1PTEN induced kinase 1. (467 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (720 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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