STRINGSTRING
ADIPOQ ADIPOQ H2ZS52_LATCH H2ZS52_LATCH SCIN SCIN H2ZS97_LATCH H2ZS97_LATCH H2ZSA7_LATCH H2ZSA7_LATCH H2ZSP9_LATCH H2ZSP9_LATCH RC3H2 RC3H2 H2ZSX8_LATCH H2ZSX8_LATCH JAG1 JAG1 CDC73 CDC73 ROR2 ROR2 IRF1 IRF1 LOC102361510 LOC102361510 H2ZX10_LATCH H2ZX10_LATCH H2ZX20_LATCH H2ZX20_LATCH H2ZX25_LATCH H2ZX25_LATCH H2ZX66_LATCH H2ZX66_LATCH CASP10 CASP10 NEDD9 NEDD9 CEBPB CEBPB PTPN6 PTPN6 MYSM1 MYSM1 SOCS5 SOCS5 H2ZZY5_LATCH H2ZZY5_LATCH CNOT4 CNOT4 MYB MYB GABPA GABPA LOC102348725 LOC102348725 GATA3 GATA3 PTPRC PTPRC TRAF6 TRAF6 H3A2R2_LATCH H3A2R2_LATCH PCID2 PCID2 MALT1 MALT1 GLI3 GLI3 CARD11 CARD11 LOC102361685 LOC102361685 BRD1 BRD1 LEO1 LEO1 FGL2 FGL2 SOS1 SOS1 TGFBR2 TGFBR2 RIPK2 RIPK2 H3A4J0_LATCH H3A4J0_LATCH H3A526_LATCH H3A526_LATCH ABCB10 ABCB10 TNFAIP6 TNFAIP6 CLDN18 CLDN18 NRARP NRARP RB1 RB1 IL10 IL10 INHBA INHBA LEF1 LEF1 H3A7T5_LATCH H3A7T5_LATCH WDR61 WDR61 PTPN2 PTPN2 LOC102362196 LOC102362196 LYN LYN MEIS1 MEIS1 SMAD7 SMAD7 DROSHA DROSHA TNFRSF11B TNFRSF11B H3ABW1_LATCH H3ABW1_LATCH CTNNBIP1 CTNNBIP1 TMEM64 TMEM64 LTA LTA NFKBIZ NFKBIZ H3AEP1_LATCH H3AEP1_LATCH H3AEV1_LATCH H3AEV1_LATCH H3AF25_LATCH H3AF25_LATCH CBFB CBFB SOS2 SOS2 ZAP70 ZAP70 DLL3 DLL3 H3AGM7_LATCH H3AGM7_LATCH H3AHE4_LATCH H3AHE4_LATCH TNFSF11 TNFSF11 LOC102351706 LOC102351706 SOCS1 SOCS1 DLL1 DLL1 H3AJR0_LATCH H3AJR0_LATCH FADD FADD CTLA4 CTLA4 FBN1 FBN1 GATA1 GATA1 HLX HLX LOC102346566 LOC102346566 LRRC17 LRRC17 TOX TOX H3AKZ9_LATCH H3AKZ9_LATCH HSPA9 HSPA9 TESC TESC H3ALU7_LATCH H3ALU7_LATCH FSTL3 FSTL3 SOX13 SOX13 H3AM65_LATCH H3AM65_LATCH CD28 CD28 RIPK1 RIPK1 BAD BAD H3APC7_LATCH H3APC7_LATCH RASGRP1 RASGRP1 SMAP1 SMAP1 H3AQ35_LATCH H3AQ35_LATCH GPR137B GPR137B SH3RF1 SH3RF1 RCOR1 RCOR1 LOC102367007 LOC102367007 H3AS02_LATCH H3AS02_LATCH H3ASA2_LATCH H3ASA2_LATCH H3ASJ2_LATCH H3ASJ2_LATCH H3ASL3_LATCH H3ASL3_LATCH SART1 SART1 PITHD1 PITHD1 RHOH RHOH PPARGC1B PPARGC1B BRAF BRAF H3AT06_LATCH H3AT06_LATCH PAF1 PAF1 TAL1 TAL1 NDFIP1 NDFIP1 IKZF3 IKZF3 SYK SYK PGLYRP2 PGLYRP2 MITF MITF MED1 MED1 H3AUI0_LATCH H3AUI0_LATCH FBXW9 FBXW9 PRELID1 PRELID1 TMEM131L TMEM131L MTURN MTURN H3AVE1_LATCH H3AVE1_LATCH STAT3 STAT3 FANCA FANCA ZFP36L2 ZFP36L2 HAX1 HAX1 INPP5D INPP5D C1QTNF9 C1QTNF9 ZEB1 ZEB1 FBXO7 FBXO7 KLF10 KLF10 H3B0U4_LATCH H3B0U4_LATCH SASH3 SASH3 METTL3 METTL3 RAB7B RAB7B H3B2C8_LATCH H3B2C8_LATCH GAS6 GAS6 TESPA1 TESPA1 SLC46A2 SLC46A2 CSF3 CSF3 H3B5B6_LATCH H3B5B6_LATCH CTNNB1 CTNNB1 CYP26B1 CYP26B1 MEIS2 MEIS2 PTN PTN ACIN1 ACIN1 H3B782_LATCH H3B782_LATCH H3B7I7_LATCH H3B7I7_LATCH LOC102353021 LOC102353021 CREB1 CREB1 DUSP10 DUSP10 LOC106701779 LOC106701779 CD74 CD74 H3B8U3_LATCH H3B8U3_LATCH FAM210B FAM210B RC3H1 RC3H1 ZBTB1 ZBTB1 CIB1 CIB1 MTOR MTOR TCF7 TCF7 H3BAX4_LATCH H3BAX4_LATCH P4HTM P4HTM LOC102346019 LOC102346019 TBX21 TBX21 NF1 NF1 TCTA TCTA MYC MYC H3BCG1_LATCH H3BCG1_LATCH HOXA5 HOXA5 ZC3H12A ZC3H12A HOXA9 HOXA9 PRMT1 PRMT1 RNF41 RNF41 NFKBIA NFKBIA PPP2R3C PPP2R3C AXL AXL FANCD2 FANCD2 TGFB1 TGFB1 FOS FOS CTR9 CTR9 ZFPM1 ZFPM1 TLR9 TLR9 RASGRP4 RASGRP4 ZBTB16 ZBTB16 CSF3R CSF3R H3BH49_LATCH H3BH49_LATCH MDK MDK FAXDC2 FAXDC2 AMBRA1 AMBRA1 UBASH3B UBASH3B EIF6 EIF6 H3BI75_LATCH H3BI75_LATCH ACVR1B ACVR1B IL18 IL18 ZFP36L1 ZFP36L1 FBXW7 FBXW7 LOC102354416 LOC102354416 LOC102356247 LOC102356247 M3XIB9_LATCH M3XIB9_LATCH LOC102356233 LOC102356233 MMP14 MMP14 SH3RF2 SH3RF2 LOC102348796 LOC102348796
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADIPOQAdiponectin, C1Q and collagen domain containing. (259 aa)
H2ZS52_LATCHPentaxin. (222 aa)
SCINScinderin. (632 aa)
H2ZS97_LATCHTNF_2 domain-containing protein. (143 aa)
H2ZSA7_LATCHNACHT domain-containing protein. (707 aa)
H2ZSP9_LATCHUncharacterized protein. (997 aa)
RC3H2RING-type domain-containing protein. (352 aa)
H2ZSX8_LATCHFibronectin type-III domain-containing protein. (243 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1220 aa)
CDC73Cell division cycle 73. (316 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (882 aa)
IRF1Interferon regulatory factor. (264 aa)
LOC102361510Pentaxin. (245 aa)
H2ZX10_LATCHUncharacterized protein. (436 aa)
H2ZX20_LATCHUncharacterized protein. (1016 aa)
H2ZX25_LATCHANK_REP_REGION domain-containing protein. (269 aa)
H2ZX66_LATCHUncharacterized protein. (641 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (539 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (901 aa)
CEBPBCCAAT/enhancer-binding protein. (291 aa)
PTPN6Protein tyrosine phosphatase non-receptor type 6. (338 aa)
MYSM1Myb like, SWIRM and MPN domains 1. (827 aa)
SOCS5Suppressor of cytokine signaling 5. (538 aa)
H2ZZY5_LATCHUncharacterized protein. (548 aa)
CNOT4CCR4-NOT transcription complex subunit 4. (764 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
GABPAGA binding protein transcription factor subunit alpha. (471 aa)
LOC102348725Uncharacterized protein. (641 aa)
GATA3GATA binding protein 3. (447 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (830 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
H3A2R2_LATCHUncharacterized protein; Belongs to the peptidase C14A family. (480 aa)
PCID2PCI domain containing 2. (452 aa)
MALT1MALT1 paracaspase. (825 aa)
GLI3GLI family zinc finger 3. (1456 aa)
CARD11Caspase recruitment domain family member 11. (1137 aa)
LOC102361685Pentaxin. (232 aa)
BRD1Bromodomain containing 1. (1190 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (674 aa)
FGL2Fibrinogen like 2. (441 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1331 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (567 aa)
H3A4J0_LATCHNACHT domain-containing protein. (800 aa)
H3A526_LATCHUncharacterized protein; Belongs to the peptidase C14A family. (486 aa)
ABCB10ATP binding cassette subfamily B member 10. (723 aa)
TNFAIP6TNF alpha induced protein 6. (279 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (276 aa)
NRARPNOTCH regulated ankyrin repeat protein. (112 aa)
RB1Uncharacterized protein. (411 aa)
IL10Interleukin 10. (185 aa)
INHBAInhibin subunit beta A. (390 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
H3A7T5_LATCHUncharacterized protein. (999 aa)
WDR61WD_REPEATS_REGION domain-containing protein. (305 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (397 aa)
LOC102362196Ig-like domain-containing protein. (206 aa)
LYNTyrosine-protein kinase. (515 aa)
MEIS1Meis homeobox 1. (466 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
DROSHADrosha ribonuclease III. (1347 aa)
TNFRSF11BTNF receptor superfamily member 11b. (409 aa)
H3ABW1_LATCHANK_REP_REGION domain-containing protein. (323 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
TMEM64Transmembrane protein 64. (350 aa)
LTALymphotoxin alpha. (166 aa)
NFKBIZNFKB inhibitor zeta. (622 aa)
H3AEP1_LATCHTranscription factor binding to IGHM enhancer 3a. (502 aa)
H3AEV1_LATCHTNF_2 domain-containing protein. (230 aa)
H3AF25_LATCHUncharacterized protein. (117 aa)
CBFBCore-binding factor subunit beta. (189 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1241 aa)
ZAP70Tyrosine-protein kinase. (609 aa)
DLL3Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (699 aa)
H3AGM7_LATCHFibronectin type-III domain-containing protein. (234 aa)
H3AHE4_LATCHUncharacterized protein. (463 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (169 aa)
LOC102351706PRELI domain containing 1b. (213 aa)
SOCS1Suppressor of cytokine signaling 1a. (190 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
H3AJR0_LATCHSRY-box transcription factor 13. (427 aa)
FADDFas associated via death domain. (193 aa)
CTLA4IG domain-containing protein. (186 aa)
FBN1Fibrillin 1. (2872 aa)
GATA1GATA binding protein 1b. (432 aa)
HLXH2.0 like homeobox. (384 aa)
LOC102346566Annexin. (343 aa)
LRRC17Leucine rich repeat containing 17. (438 aa)
TOXThymocyte selection associated high mobility group box. (392 aa)
H3AKZ9_LATCHNACHT domain-containing protein. (657 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (647 aa)
TESCTescalcin. (218 aa)
H3ALU7_LATCHNACHT domain-containing protein. (877 aa)
FSTL3Follistatin like 3. (248 aa)
SOX13Uncharacterized protein. (195 aa)
H3AM65_LATCHMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (472 aa)
CD28Ig-like domain-containing protein. (202 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (667 aa)
BADUncharacterized protein. (175 aa)
H3APC7_LATCHNACHT domain-containing protein. (686 aa)
RASGRP1RAS guanyl releasing protein 1. (719 aa)
SMAP1Small ArfGAP 1. (474 aa)
H3AQ35_LATCHNACHT domain-containing protein. (880 aa)
GPR137BG protein-coupled receptor 137B. (349 aa)
SH3RF1SH3 domain containing ring finger 1. (745 aa)
RCOR1REST corepressor 1. (272 aa)
LOC102367007Uncharacterized protein. (335 aa)
H3AS02_LATCHUncharacterized protein. (291 aa)
H3ASA2_LATCHIg-like domain-containing protein. (290 aa)
H3ASJ2_LATCHANK_REP_REGION domain-containing protein. (303 aa)
H3ASL3_LATCHSi:ch211-203k16.3. (394 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (649 aa)
PITHD1PITH domain containing 1. (209 aa)
RHOHRas homolog family member H. (189 aa)
PPARGC1BPPARG coactivator 1 beta. (986 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (768 aa)
H3AT06_LATCHUncharacterized protein. (88 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (530 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (327 aa)
NDFIP1Nedd4 family interacting protein 1. (212 aa)
IKZF3IKAROS family zinc finger 3. (507 aa)
SYKTyrosine-protein kinase. (616 aa)
PGLYRP2Peptidoglycan recognition protein 2. (429 aa)
MITFMelanocyte inducing transcription factor. (486 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1401 aa)
H3AUI0_LATCHNACHT domain-containing protein. (572 aa)
FBXW9F-box and WD repeat domain containing 9. (465 aa)
PRELID1PRELI domain containing 1. (216 aa)
TMEM131LTransmembrane 131 like. (1522 aa)
MTURNMaturin, neural progenitor differentiation regulator homolog. (131 aa)
H3AVE1_LATCHNACHT domain-containing protein. (574 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
FANCAFA complementation group A. (1436 aa)
ZFP36L2Uncharacterized protein. (394 aa)
HAX1HCLS1 associated protein X-1. (249 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1144 aa)
C1QTNF9C1q domain-containing protein. (198 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1076 aa)
FBXO7F-box protein 7. (482 aa)
KLF10Kruppel like factor 10. (476 aa)
H3B0U4_LATCHMALT paracaspase 2. (695 aa)
SASH3SAM and SH3 domain containing 3. (433 aa)
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
RAB7BRAB7B, member RAS oncogene family. (201 aa)
H3B2C8_LATCHUncharacterized protein. (389 aa)
GAS6Uncharacterized protein. (681 aa)
TESPA1KRAP_IP3R_bind domain-containing protein. (96 aa)
SLC46A2Solute carrier family 46 member 2. (461 aa)
CSF3Colony stimulating factor 3. (210 aa)
H3B5B6_LATCHNACHT domain-containing protein. (692 aa)
CTNNB1Catenin beta 1. (781 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (511 aa)
MEIS2Meis homeobox 2. (477 aa)
PTNPleiotrophin. (167 aa)
ACIN1SAP domain-containing protein. (1277 aa)
H3B782_LATCHSi:ch211-157b11.8. (221 aa)
H3B7I7_LATCHSb:cb81. (360 aa)
LOC102353021Uncharacterized protein. (644 aa)
CREB1cAMP responsive element binding protein 1. (347 aa)
DUSP10Dual specificity phosphatase 10. (481 aa)
LOC106701779Uncharacterized protein. (373 aa)
CD74CD74 molecule. (279 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
FAM210BFamily with sequence similarity 210 member B. (163 aa)
RC3H1Ring finger and CCCH-type domains 1. (1123 aa)
ZBTB1Zinc finger and BTB domain containing 1. (706 aa)
CIB1Calcium and integrin binding 1. (190 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
TCF7Transcription factor 7. (343 aa)
H3BAX4_LATCHDC_STAMP domain-containing protein. (450 aa)
P4HTMProlyl 4-hydroxylase, transmembrane. (512 aa)
LOC102346019C1q domain-containing protein. (226 aa)
TBX21T-box transcription factor 21. (570 aa)
NF1Neurofibromin 1. (2814 aa)
TCTAT-cell leukemia translocation-altered gene protein homolog. (102 aa)
MYCTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (412 aa)
H3BCG1_LATCHSET domain-containing protein. (714 aa)
HOXA5Homeobox A5. (269 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (600 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (261 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (320 aa)
RNF41Ring finger protein 41. (319 aa)
NFKBIANuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (298 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (451 aa)
AXLAXL receptor tyrosine kinase. (872 aa)
FANCD2FA complementation group D2. (1462 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (391 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1163 aa)
ZFPM1Zinc finger protein, FOG family member 1. (1017 aa)
TLR9Toll-like receptor 9. (1039 aa)
RASGRP4RAS guanyl releasing protein 4. (692 aa)
ZBTB16Zinc finger and BTB domain containing 16. (420 aa)
CSF3RColony stimulating factor 3 receptor. (826 aa)
H3BH49_LATCHIg-like domain-containing protein. (195 aa)
MDKMidkine. (141 aa)
FAXDC2Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (337 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1195 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (607 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (136 aa)
H3BI75_LATCHUncharacterized protein. (110 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (489 aa)
IL18Uncharacterized protein. (200 aa)
ZFP36L1ZFP36 ring finger protein like 1. (346 aa)
FBXW7F-box and WD repeat domain containing 7. (713 aa)
LOC102354416Uncharacterized protein. (160 aa)
LOC102356247Uncharacterized protein. (636 aa)
M3XIB9_LATCHPentaxin. (231 aa)
LOC102356233TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (574 aa)
MMP14Matrix metallopeptidase 14. (597 aa)
SH3RF2SH3 domain containing ring finger 2. (787 aa)
LOC102348796Uncharacterized protein. (497 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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