STRINGSTRING
LOC102352804 LOC102352804 CAV3 CAV3 WNK1 WNK1 LOC102354490 LOC102354490 PINK1 PINK1 AMIGO1 AMIGO1 EDN1 EDN1 RNF207 RNF207 WNK2 WNK2 ABCC8 ABCC8 BAK1 BAK1 H3B845_LATCH H3B845_LATCH LOC102350639 LOC102350639 DRD4 DRD4 KCNE1 KCNE1 ACE2 ACE2 CLTRN CLTRN H3B1J8_LATCH H3B1J8_LATCH STAC2 STAC2 ADCYAP1R1 ADCYAP1R1 CACNB4 CACNB4 H3ATR2_LATCH H3ATR2_LATCH TRPC1 TRPC1 AKAP7 AKAP7 LOC102359041 LOC102359041 STIM1 STIM1 LOC102364622 LOC102364622 CACNG4 CACNG4 AKAP6 AKAP6 TESC TESC KCNQ1 KCNQ1 CDK5 CDK5 LRRC38 LRRC38 H3AHJ4_LATCH H3AHJ4_LATCH LOC102357829 LOC102357829 H3AF01_LATCH H3AF01_LATCH GPER1 GPER1 PDZK1 PDZK1 BAX BAX CHP1 CHP1 HTT HTT ANO6 ANO6 EDNRA EDNRA AMIGO3 AMIGO3 R3HDM1 R3HDM1 ATP1B3 ATP1B3 APLNR APLNR H3A855_LATCH H3A855_LATCH WNK3 WNK3 PKD2 PKD2 SHANK3 SHANK3 LOC102363383 LOC102363383 STAC STAC P2RX1 P2RX1 LRRC55 LRRC55 LOC102352528 LOC102352528 H3A068_LATCH H3A068_LATCH CACNG2 CACNG2 RAMP3 RAMP3 LOC102362749 LOC102362749 WNK4 WNK4 STIM2 STIM2 ATPSCKMT ATPSCKMT H2ZTT6_LATCH H2ZTT6_LATCH LOC102355203 LOC102355203 LOC102351466 LOC102351466 CNTD1 CNTD1 LOC102353789 LOC102353789 H3BGE9_LATCH H3BGE9_LATCH F2 F2 PLCG1 PLCG1 R3HDM2 R3HDM2 STAC3 STAC3 RELN RELN VMP1 VMP1 CHP2 CHP2 P2RX4 P2RX4 LOC102359410 LOC102359410 G6PD G6PD THY1 THY1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102352804Phosphoinositide phospholipase C. (1172 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
WNK1WNK lysine deficient protein kinase 1. (2654 aa)
LOC102354490Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (356 aa)
PINK1PTEN induced kinase 1. (467 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (506 aa)
EDN1Endothelin 1. (216 aa)
RNF207Ring finger protein 207. (648 aa)
WNK2WNK lysine deficient protein kinase 2. (1994 aa)
ABCC8ATP binding cassette subfamily C member 8. (1591 aa)
BAK1BCL2 antagonist/killer 1. (239 aa)
H3B845_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (299 aa)
LOC102350639G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (382 aa)
KCNE1Uncharacterized protein. (122 aa)
ACE2Angiotensin-converting enzyme. (814 aa)
CLTRNCollectrin domain-containing protein. (226 aa)
H3B1J8_LATCHAKAP7_NLS domain-containing protein. (240 aa)
STAC2SH3 and cysteine rich domain 2. (375 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (337 aa)
CACNB4Calcium channel, voltage-dependent, beta 4a subunit. (477 aa)
H3ATR2_LATCHUncharacterized protein. (282 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
AKAP7A-kinase anchoring protein 7. (427 aa)
LOC102359041Zgc:153993. (208 aa)
STIM1Stromal interaction molecule 1. (662 aa)
LOC102364622Si:dkey-190g11.3. (221 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (329 aa)
AKAP6Uncharacterized protein. (901 aa)
TESCTescalcin. (218 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
CDK5Cyclin dependent kinase 5. (290 aa)
LRRC38Leucine rich repeat containing 38. (292 aa)
H3AHJ4_LATCHIon_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
LOC102357829G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (313 aa)
H3AF01_LATCHUncharacterized protein. (658 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
PDZK1PDZ domain containing 1. (523 aa)
BAXUncharacterized protein. (223 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
HTTHuntingtin. (3125 aa)
ANO6Anoctamin. (766 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (510 aa)
R3HDM1R3H domain containing 1. (1107 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
H3A855_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (320 aa)
WNK3WNK lysine deficient protein kinase 3. (1769 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (890 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1187 aa)
LOC102363383EF-hand domain-containing protein; Belongs to the S-100 family. (100 aa)
STACSH3 and cysteine rich domain. (279 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (403 aa)
LRRC55Leucine rich repeat containing 55. (283 aa)
LOC102352528G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa)
H3A068_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein. (326 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (225 aa)
RAMP3Receptor activity modifying protein 3. (117 aa)
LOC102362749Interfer-bind domain-containing protein. (265 aa)
WNK4WNK lysine deficient protein kinase 4. (1163 aa)
STIM2Stromal interaction molecule 2. (639 aa)
ATPSCKMTATP synthase c subunit lysine N-methyltransferase. (217 aa)
H2ZTT6_LATCHPhosphoinositide phospholipase C. (404 aa)
LOC102355203Na_H_Exchanger domain-containing protein. (161 aa)
LOC102351466Uncharacterized protein. (201 aa)
CNTD1Cyclin N-terminal domain containing 1. (274 aa)
LOC102353789G_PROTEIN_RECEP_F1_2 domain-containing protein. (344 aa)
H3BGE9_LATCHUncharacterized protein. (273 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (618 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1219 aa)
R3HDM2R3H domain containing 2. (971 aa)
STAC3SH3 and cysteine rich domain 3. (373 aa)
RELNReelin. (3462 aa)
VMP1Vacuole membrane protein 1. (406 aa)
CHP2Calcineurin like EF-hand protein 2. (194 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
LOC102359410G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (387 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
THY1Thy-1 cell surface antigen. (165 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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