(49 nodes) Regulation of response to endoplasmic reticulum stress network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DDRGK1	DDRGK domain containing 1. (243 aa)
	ATF6	Activating transcription factor 6. (355 aa)
	SVIP	Si:ch73-147o17.1. (80 aa)
	AQP11	Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
	BAX	Uncharacterized protein. (223 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (397 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (439 aa)
	NCK1	Cytoplasmic protein. (377 aa)
	OPA1	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (994 aa)
	BAG6	BCL2 associated athanogene 6. (995 aa)
	BFAR	Bifunctional apoptosis regulator. (454 aa)
	SGTA	Small glutamine rich tetratricopeptide repeat containing alpha. (316 aa)
	COPS5	COP9 signalosome subunit 5. (334 aa)
	TMEM33	Transmembrane protein 33. (245 aa)
	LPCAT3	Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (430 aa)
	CREB3	cAMP responsive element binding protein 3. (452 aa)
	H2ZTK5_LATCH	Peptidase_M50 domain-containing protein. (221 aa)
	EIF2AK3	Eukaryotic translation initiation factor 2 alpha kinase 3. (958 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (375 aa)
	CREB3L1	cAMP responsive element binding protein 3 like 1. (481 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	SELENOS	Selenoprotein S. (189 aa)
	UBXN1	UBX domain protein 1. (320 aa)
	MANF	Mesencephalic astrocyte derived neurotrophic factor. (193 aa)
	PDX1	Pancreatic and duodenal homeobox 1. (257 aa)
	RNF183	Ring finger protein 183. (191 aa)
	BAK1	BCL2 antagonist/killer 1. (239 aa)
	TMEM259	Transmembrane protein 259. (583 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (426 aa)
	USP19	Ubiquitin specific peptidase 19. (1382 aa)
	USP14	Ubiquitin carboxyl-terminal hydrolase. (490 aa)
	USP13	Ubiquitin carboxyl-terminal hydrolase. (863 aa)
	H3B2C8_LATCH	Uncharacterized protein. (389 aa)
	LOC102363778	J domain-containing protein. (211 aa)
	H3AY58_LATCH	BZIP domain-containing protein. (530 aa)
	RNFT1	Ring finger protein, transmembrane 1. (412 aa)
	LRRK2	Leucine rich repeat kinase 2. (2508 aa)
	WFS1	Wolframin ER transmembrane glycoprotein. (876 aa)
	RNFT2	Ring finger protein, transmembrane 2. (445 aa)
	LOC102359041	Zgc:153993. (208 aa)
	TXNDC12	Thioredoxin domain containing 12. (173 aa)
	DNAJB9	DnaJ heat shock protein family (Hsp40) member B9. (219 aa)
	HERPUD1	Homocysteine inducible ER protein with ubiquitin like domain 1. (393 aa)
	UFL1	UFM1 specific ligase 1. (792 aa)
	NCK2	Cytoplasmic protein. (380 aa)
	BOK	BCL2 family apoptosis regulator BOK. (111 aa)
	SIRT1	Sirtuin 1. (729 aa)
	FICD	FIC domain containing. (458 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF6	CREB3	ENSLACP00000008653	ENSLACP00000008681	Activating transcription factor 6.	cAMP responsive element binding protein 3.	0.502
ATF6	CREB3L1	ENSLACP00000008653	ENSLACP00000021137	Activating transcription factor 6.	cAMP responsive element binding protein 3 like 1.	0.564
ATF6	EIF2AK3	ENSLACP00000008653	ENSLACP00000022169	Activating transcription factor 6.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.704
ATF6	H2ZTK5_LATCH	ENSLACP00000008653	ENSLACP00000000726	Activating transcription factor 6.	Peptidase_M50 domain-containing protein.	0.862
ATF6	H3B2C8_LATCH	ENSLACP00000008653	ENSLACP00000016049	Activating transcription factor 6.	Uncharacterized protein.	0.855
ATF6	HSPA5	ENSLACP00000008653	ENSLACP00000020775	Activating transcription factor 6.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.912
ATF6	WFS1	ENSLACP00000008653	ENSLACP00000013099	Activating transcription factor 6.	Wolframin ER transmembrane glycoprotein.	0.924
BAG6	SGTA	ENSLACP00000003772	ENSLACP00000003207	BCL2 associated athanogene 6.	Small glutamine rich tetratricopeptide repeat containing alpha.	0.916
BAG6	UBXN1	ENSLACP00000003772	ENSLACP00000020412	BCL2 associated athanogene 6.	UBX domain protein 1.	0.937
BAK1	BAX	ENSLACP00000018296	ENSLACP00000007049	BCL2 antagonist/killer 1.	Uncharacterized protein.	0.985
BAK1	LOC102359041	ENSLACP00000018296	ENSLACP00000012675	BCL2 antagonist/killer 1.	Zgc:153993.	0.900
BAX	BAK1	ENSLACP00000007049	ENSLACP00000018296	Uncharacterized protein.	BCL2 antagonist/killer 1.	0.985
BAX	LOC102359041	ENSLACP00000007049	ENSLACP00000012675	Uncharacterized protein.	Zgc:153993.	0.975
COPS5	USP14	ENSLACP00000002782	ENSLACP00000016665	COP9 signalosome subunit 5.	Ubiquitin carboxyl-terminal hydrolase.	0.884
CREB3	ATF6	ENSLACP00000008681	ENSLACP00000008653	cAMP responsive element binding protein 3.	Activating transcription factor 6.	0.502
CREB3	H2ZTK5_LATCH	ENSLACP00000008681	ENSLACP00000000726	cAMP responsive element binding protein 3.	Peptidase_M50 domain-containing protein.	0.780
CREB3L1	ATF6	ENSLACP00000021137	ENSLACP00000008653	cAMP responsive element binding protein 3 like 1.	Activating transcription factor 6.	0.564
CREB3L1	H2ZTK5_LATCH	ENSLACP00000021137	ENSLACP00000000726	cAMP responsive element binding protein 3 like 1.	Peptidase_M50 domain-containing protein.	0.767
DDRGK1	UFL1	ENSLACP00000001026	ENSLACP00000010739	DDRGK domain containing 1.	UFM1 specific ligase 1.	0.949
DNAJB9	H3B2C8_LATCH	ENSLACP00000011504	ENSLACP00000016049	DnaJ heat shock protein family (Hsp40) member B9.	Uncharacterized protein.	0.596