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GPD1 GPD1 NDUFAB1 NDUFAB1 NDUFV2 NDUFV2 NDUFB2 NDUFB2 GPD2 GPD2 NDUFS4 NDUFS4 LOC102356776 LOC102356776 NOXA1 NOXA1 PDHB PDHB HSD17B8 HSD17B8 SDHC SDHC NDUFB10 NDUFB10 DBT DBT NDUFS8 NDUFS8 NDUFS5 NDUFS5 GPD1L GPD1L NDUFB5 NDUFB5 NDUFB4 NDUFB4 NDUFB3 NDUFB3 NDUFS1 NDUFS1 DLAT DLAT SDHD SDHD SDHB SDHB NDUFB6 NDUFB6 NDUFS2 NDUFS2 UQCRB UQCRB NDUFA6 NDUFA6 NDUFS6 NDUFS6 GMPR2 GMPR2 LOC102354581 LOC102354581 H3BAN4_LATCH H3BAN4_LATCH NDUFA7 NDUFA7 NCF1 NCF1 LOC102365732 LOC102365732 FOXRED1 FOXRED1 NCF2 NCF2 NDUFB9 NDUFB9 NCF4 NCF4 UQCRFS1 UQCRFS1 DUOX2 DUOX2 H3A2Y1_LATCH H3A2Y1_LATCH UQCR10 UQCR10 PDHA1 PDHA1 CYC1 CYC1 NDUFA9 NDUFA9 MRPS36 MRPS36 IDH3B IDH3B NOX4 NOX4 PDHX PDHX CBR4 CBR4 NDUFB8 NDUFB8 BCKDHA BCKDHA WDR93 WDR93 NDUFB7 NDUFB7 NDUFA12 NDUFA12 NDUFV3 NDUFV3 NDUFA3 NDUFA3 BCKDK BCKDK GLDC GLDC NDUFA1 NDUFA1 UQCRQ UQCRQ H3AIU3_LATCH H3AIU3_LATCH NDUFA13 NDUFA13 RRM1 RRM1 NDUFA8 NDUFA8 LOC102362883 LOC102362883 CAT CAT IDH3G IDH3G SDHA SDHA CYBA CYBA NDUFV1 NDUFV1 NDUFA4 NDUFA4 GMPR GMPR NDUFA2 NDUFA2 GCSH GCSH IDH3A IDH3A NDUFC2 NDUFC2 OGDHL OGDHL NDUFS7 NDUFS7 ETFA ETFA NDUFA5 NDUFA5 CYTB CYTB NDUFS3 NDUFS3 DLST DLST LOC102356109 LOC102356109 NOXO1 NOXO1 BCKDHB BCKDHB NDUFA10 NDUFA10 DLD DLD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (350 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (157 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (231 aa)
NDUFB2NADH:ubiquinone oxidoreductase subunit B2. (101 aa)
GPD2Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (727 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (169 aa)
LOC102356776Glycerol-3-phosphate dehydrogenase [NAD(+)]. (348 aa)
NOXA1NADPH oxidase activator 1. (573 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (393 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (255 aa)
SDHCSuccinate dehydrogenase complex subunit C. (168 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (174 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (492 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (209 aa)
NDUFS5NADH:ubiquinone oxidoreductase subunit S5. (106 aa)
GPD1LGlycerol-3-phosphate dehydrogenase [NAD(+)]. (351 aa)
NDUFB5NADH:ubiquinone oxidoreductase subunit B5. (122 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (128 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (94 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (732 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (629 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (156 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (285 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (129 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (466 aa)
UQCRBCytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (117 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (127 aa)
NDUFS6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (350 aa)
LOC102354581Uncharacterized protein. (56 aa)
H3BAN4_LATCHOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (773 aa)
NDUFA7NADH:ubiquinone oxidoreductase subunit A7. (127 aa)
NCF1Neutrophil cytosolic factor 1. (416 aa)
LOC102365732Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (90 aa)
FOXRED1FAD dependent oxidoreductase domain containing 1. (468 aa)
NCF2Neutrophil cytosolic factor 2. (568 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (175 aa)
NCF4Neutrophil cytosolic factor 4. (360 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (277 aa)
DUOX2Dual oxidase 2. (1551 aa)
H3A2Y1_LATCHUncharacterized protein. (427 aa)
UQCR10Ubiquinol-cytochrome c reductase, complex III subunit X. (62 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
CYC1Cytochrome c1. (304 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (305 aa)
MRPS36Mitochondrial ribosomal protein S36. (100 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (363 aa)
NOX4NADPH oxidase 4. (541 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (534 aa)
CBR4Carbonyl reductase 4. (237 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
BCKDHA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (446 aa)
WDR93WD repeat domain 93. (661 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (94 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (146 aa)
NDUFV3NADH:ubiquinone oxidoreductase subunit V3. (458 aa)
NDUFA3NADH:ubiquinone oxidoreductase subunit A3. (86 aa)
BCKDKProtein-serine/threonine kinase. (408 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (914 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (108 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
H3AIU3_LATCHDihydrolipoamide dehydrogenase. (233 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (763 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
LOC102362883Iso_dh domain-containing protein. (384 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (521 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (400 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (670 aa)
CYBACytochrome b-245 alpha chain. (187 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (475 aa)
NDUFA4NDUFA4 mitochondrial complex associated. (82 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (96 aa)
GCSHGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (177 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (110 aa)
OGDHLOxoglutarate dehydrogenase like. (1017 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (179 aa)
ETFAUncharacterized protein. (232 aa)
NDUFA5Uncharacterized protein. (82 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (380 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3. (255 aa)
DLSTDihydrolipoamide S-succinyltransferase. (458 aa)
LOC102356109ETF domain-containing protein. (127 aa)
NOXO1Uncharacterized protein. (488 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (217 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (358 aa)
DLDDihydrolipoamide dehydrogenase. (236 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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