(44 nodes) Potassium ion import across plasma membrane network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KCNJ11	Potassium voltage-gated channel subfamily J member 11. (392 aa)
	LOC102360278	Uncharacterized protein. (1069 aa)
	LOC102353803	Zgc:162160. (421 aa)
	KCNJ9	Potassium voltage-gated channel subfamily J member 9. (424 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (305 aa)
	KCNE2	Potassium voltage-gated channel subfamily E regulatory subunit 2. (125 aa)
	KCNJ10	Potassium voltage-gated channel subfamily J member 10. (378 aa)
	KCNJ16	Potassium voltage-gated channel subfamily J member 16. (363 aa)
	KCNJ2	Potassium voltage-gated channel subfamily J member 2. (427 aa)
	H3ATR2_LATCH	Uncharacterized protein. (282 aa)
	ATP1A3	Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
	LOC102353550	Potassium voltage-gated channel, subfamily J, member 19b. (272 aa)
	ATP1B3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
	LOC102364761	Uncharacterized protein. (974 aa)
	SLC12A8	Solute carrier family 12 member 8. (716 aa)
	LOC102353246	Uncharacterized protein. (374 aa)
	ATP4A	Sodium/potassium-transporting ATPase subunit alpha. (1033 aa)
	KCNJ3	Potassium voltage-gated channel subfamily J member 3. (298 aa)
	SLC12A4	Uncharacterized protein. (1056 aa)
	KCNJ15	Potassium voltage-gated channel subfamily J member 15. (374 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (1033 aa)
	KCNJ13	Potassium voltage-gated channel subfamily J member 13. (366 aa)
	LOC102348624	Solute carrier family 12 member 10, tandem duplicate 3. (1008 aa)
	ATP1A2	Sodium/potassium-transporting ATPase subunit alpha. (780 aa)
	KCNJ6	Potassium voltage-gated channel subfamily J member 6. (423 aa)
	LOC102355428	Uncharacterized protein. (949 aa)
	LOC102359024	Potassium inwardly-rectifying channel, subfamily J, member 12b. (432 aa)
	KCNJ4	Potassium voltage-gated channel subfamily J member 4. (427 aa)
	KCNJ8	Potassium voltage-gated channel subfamily J member 8. (417 aa)
	H3AHJ4_LATCH	Ion_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
	H3AKZ6_LATCH	Si:ch211-113j13.2. (396 aa)
	ATP4B	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (293 aa)
	KCNK5	Potassium two pore domain channel subfamily K member 5. (393 aa)
	SLC12A2	Solute carrier family 12 member 2. (1179 aa)
	SLC12A1	Solute carrier family 12 member 1. (1102 aa)
	SLC12A5	Uncharacterized protein. (951 aa)
	H3APG2_LATCH	Uncharacterized protein. (66 aa)
	SLC12A3	Solute carrier family 12 member 3. (1040 aa)
	KCNJ14	Potassium voltage-gated channel subfamily J member 14. (440 aa)
	H3BGW3_LATCH	Uncharacterized protein. (382 aa)
	LOC102359288	Potassium inwardly-rectifying channel, subfamily J, member 11, like. (370 aa)
	KCNJ5	Potassium voltage-gated channel subfamily J member 5. (309 aa)
	KCNJ1	Potassium voltage-gated channel subfamily J member 1. (373 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1A1	ATP1A2	ENSLACP00000001627	ENSLACP00000000537	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
ATP1A1	ATP1B1	ENSLACP00000001627	ENSLACP00000016128	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.994
ATP1A1	ATP1B3	ENSLACP00000001627	ENSLACP00000005948	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.978
ATP1A1	ATP4B	ENSLACP00000001627	ENSLACP00000013673	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.821
ATP1A1	H3ATR2_LATCH	ENSLACP00000001627	ENSLACP00000013033	Sodium/potassium-transporting ATPase subunit alpha.	Uncharacterized protein.	0.700
ATP1A2	ATP1A1	ENSLACP00000000537	ENSLACP00000001627	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.901
ATP1A2	ATP1B1	ENSLACP00000000537	ENSLACP00000016128	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.991
ATP1A2	ATP1B3	ENSLACP00000000537	ENSLACP00000005948	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.970
ATP1A2	ATP4B	ENSLACP00000000537	ENSLACP00000013673	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.946
ATP1A2	H3ATR2_LATCH	ENSLACP00000000537	ENSLACP00000013033	Sodium/potassium-transporting ATPase subunit alpha.	Uncharacterized protein.	0.713
ATP1A3	ATP1B1	ENSLACP00000014509	ENSLACP00000016128	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.921
ATP1A3	ATP1B3	ENSLACP00000014509	ENSLACP00000005948	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.700
ATP1A3	ATP4B	ENSLACP00000014509	ENSLACP00000013673	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.821
ATP1A3	H3ATR2_LATCH	ENSLACP00000014509	ENSLACP00000013033	Sodium/potassium-transporting ATPase subunit alpha.	Uncharacterized protein.	0.700
ATP1A3	SLC12A1	ENSLACP00000014509	ENSLACP00000008129	Sodium/potassium-transporting ATPase subunit alpha.	Solute carrier family 12 member 1.	0.453
ATP1A3	SLC12A2	ENSLACP00000014509	ENSLACP00000008394	Sodium/potassium-transporting ATPase subunit alpha.	Solute carrier family 12 member 2.	0.450
ATP1B1	ATP1A1	ENSLACP00000016128	ENSLACP00000001627	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Sodium/potassium-transporting ATPase subunit alpha.	0.994
ATP1B1	ATP1A2	ENSLACP00000016128	ENSLACP00000000537	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Sodium/potassium-transporting ATPase subunit alpha.	0.991
ATP1B1	ATP1A3	ENSLACP00000016128	ENSLACP00000014509	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Sodium/potassium-transporting ATPase subunit alpha.	0.921
ATP1B1	ATP1B3	ENSLACP00000016128	ENSLACP00000005948	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.949