STRINGSTRING
CACNB4 CACNB4 CCND1 CCND1 FBXO7 FBXO7 LOC102345953 LOC102345953 CDKN2D CDKN2D TP53 TP53 E2F7 E2F7 PRKDC PRKDC H3B277_LATCH H3B277_LATCH JADE1 JADE1 LOC102365218 LOC102365218 ANKRD17 ANKRD17 LSM11 LSM11 MTBP MTBP LSM10 LSM10 KMT2E KMT2E H3B8G4_LATCH H3B8G4_LATCH CDK7 CDK7 STOX1 STOX1 FHL1 FHL1 CRLF3 CRLF3 CCND2 CCND2 BCL7A BCL7A MNAT1 MNAT1 AMBRA1 AMBRA1 DACT1 DACT1 GTSE1 GTSE1 RPTOR RPTOR CRADD CRADD APPL2 APPL2 LOC102345100 LOC102345100 H2ZSY2_LATCH H2ZSY2_LATCH PLRG1 PLRG1 PSME2 PSME2 LOC102356560 LOC102356560 CDC73 CDC73 H2ZWA0_LATCH H2ZWA0_LATCH LOC102367471 LOC102367471 SDE2 SDE2 PTPN6 PTPN6 AIF1 AIF1 CASP2 CASP2 RBL2 RBL2 PSME1 PSME1 CCNH CCNH RFWD3 RFWD3 WAC WAC PKD1 PKD1 CUL4A CUL4A TM4SF5 TM4SF5 PKD2 PKD2 CTDSP1 CTDSP1 CUL4B CUL4B RB1 RB1 CTDSPL CTDSPL INHBA INHBA BRD7 BRD7 CDKN2C CDKN2C DCUN1D3 DCUN1D3 E2F1 E2F1 MBLAC1 MBLAC1 LOC102348760 LOC102348760 RRM1 RRM1 CPSF3 CPSF3 BCL7C BCL7C INO80 INO80 ECD ECD KANK2 KANK2 LOC102346566 LOC102346566 CTDSP2 CTDSP2 KIF14 KIF14 ADAM17 ADAM17 FBXO31 FBXO31 RBL1 RBL1 STIL STIL APPL1 APPL1 TFDP1 TFDP1 RGCC RGCC DDR2 DDR2 MEPCE MEPCE GPNMB GPNMB SASS6 SASS6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACNB4Calcium channel, voltage-dependent, beta 4a subunit. (477 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (292 aa)
FBXO7F-box protein 7. (482 aa)
LOC102345953Cyclin D3; Belongs to the cyclin family. (292 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (168 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
E2F7Uncharacterized protein. (373 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4083 aa)
H3B277_LATCHUncharacterized protein. (4290 aa)
JADE1Jade family PHD finger 1. (864 aa)
LOC102365218Uncharacterized protein. (210 aa)
ANKRD17Ankyrin repeat domain 17. (2394 aa)
LSM11LSM11, U7 small nuclear RNA associated. (338 aa)
MTBPMDM2 binding protein. (877 aa)
LSM10LSM10, U7 small nuclear RNA associated. (130 aa)
KMT2ELysine methyltransferase 2E. (1846 aa)
H3B8G4_LATCHUncharacterized protein. (110 aa)
CDK7Cyclin dependent kinase 7. (210 aa)
STOX1Storkhead box 1. (891 aa)
FHL1Four and a half LIM domains 1. (232 aa)
CRLF3Cytokine receptor like factor 3. (440 aa)
CCND2Cyclin D2, b; Belongs to the cyclin family. (291 aa)
BCL7ABAF chromatin remodeling complex subunit BCL7A. (236 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1195 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (815 aa)
GTSE1GTSE1_N domain-containing protein. (721 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1334 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (143 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (484 aa)
LOC102345100Zgc:172079. (204 aa)
H2ZSY2_LATCHUncharacterized protein. (345 aa)
PLRG1Pleiotropic regulator 1. (514 aa)
PSME2Proteasome activator subunit 2. (241 aa)
LOC102356560ANK_REP_REGION domain-containing protein. (128 aa)
CDC73Cell division cycle 73. (316 aa)
H2ZWA0_LATCHUncharacterized protein. (591 aa)
LOC102367471Uncharacterized protein; Belongs to the cyclin family. (292 aa)
SDE2SDE2 telomere maintenance homolog. (418 aa)
PTPN6Protein tyrosine phosphatase non-receptor type 6. (338 aa)
AIF1Allograft inflammatory factor 1. (119 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (433 aa)
RBL2RB transcriptional corepressor like 2. (1109 aa)
PSME1Proteasome activator subunit 1. (252 aa)
CCNHCyclin H; Belongs to the cyclin family. (329 aa)
RFWD3Ring finger and WD repeat domain 3. (727 aa)
WACWW domain containing adaptor with coiled-coil. (643 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4241 aa)
CUL4ACullin 4A; Belongs to the cullin family. (851 aa)
TM4SF5Transmembrane 4 L six family member 5. (153 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (890 aa)
CTDSP1CTD small phosphatase 1. (260 aa)
CUL4BCullin 4B; Belongs to the cullin family. (845 aa)
RB1Uncharacterized protein. (411 aa)
CTDSPLCTD small phosphatase like. (283 aa)
INHBAInhibin subunit beta A. (390 aa)
BRD7Bromodomain containing 7. (638 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (169 aa)
DCUN1D3DCN1-like protein. (304 aa)
E2F1E2F transcription factor 1. (411 aa)
MBLAC1Metallo-beta-lactamase domain containing 1. (216 aa)
LOC102348760Uncharacterized protein. (782 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (763 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (689 aa)
BCL7CUncharacterized protein. (219 aa)
INO80INO80 complex ATPase subunit. (1542 aa)
ECDEcdysoneless cell cycle regulator. (636 aa)
KANK2KN motif and ankyrin repeat domains 2. (1279 aa)
LOC102346566Annexin. (343 aa)
CTDSP2CTD small phosphatase 2. (271 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1644 aa)
ADAM17ADAM metallopeptidase domain 17. (827 aa)
FBXO31F-box protein 31. (594 aa)
RBL1RB transcriptional corepressor like 1. (1084 aa)
STILSTIL centriolar assembly protein. (1298 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (709 aa)
TFDP1Transcription factor. (412 aa)
RGCCRegulator of cell cycle. (127 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (838 aa)
MEPCEMethylphosphate capping enzyme. (437 aa)
GPNMBGlycoprotein nmb. (607 aa)
SASS6SAS-6 centriolar assembly protein. (567 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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