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PTCH1 | Patched 1. (1287 aa) | ||||
KDF1 | Keratinocyte differentiation factor 1. (380 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa) | ||||
FBLN1 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (701 aa) | ||||
NR2E1 | Nuclear receptor subfamily 2 group E member 1. (477 aa) | ||||
NF1 | Neurofibromin 1. (2814 aa) | ||||
GLI3 | GLI family zinc finger 3. (1456 aa) | ||||
CDKN2C | Cyclin dependent kinase inhibitor 2C. (169 aa) |