(31 nodes) Late endosome membrane network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3AXK0_LATCH	Uncharacterized protein. (161 aa)
	LAMTOR3	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
	LAPTM4B	Lysosomal protein transmembrane 4 beta. (117 aa)
	MARCHF1	Membrane associated ring-CH-type finger 1. (496 aa)
	MREG	Uncharacterized protein. (186 aa)
	SORL1	Sortilin-related receptor, L(DLR class) A repeats containing. (1410 aa)
	LAMTOR2	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
	ATP13A3	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1232 aa)
	C9orf85	Chromosome 9 open reading frame 85. (211 aa)
	LOC102364374	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1154 aa)
	WDR81	WD repeat domain 81. (1916 aa)
	LAPTM4A	Lysosomal protein transmembrane 4 alpha. (237 aa)
	CDIP1	Cell death inducing p53 target 1. (210 aa)
	H3B7E6_LATCH	Uncharacterized protein. (237 aa)
	ATP13A2	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1091 aa)
	LOC102366418	Zgc:91968. (232 aa)
	TMEM9B	TMEM9 domain family member B. (194 aa)
	TMEM9	Transmembrane protein 9. (191 aa)
	CYB561A3	Cytochrome b561 family member A3. (245 aa)
	ABCB6	ATP binding cassette subfamily B member 6 (Langereis blood group). (776 aa)
	VTI1B	Vesicle transport through interaction with t-SNAREs 1B. (235 aa)
	LAMTOR5	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (92 aa)
	LITAF	LITAF domain-containing protein. (290 aa)
	LAMTOR4	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (103 aa)
	C7orf25	Chromosome 7 open reading frame 25. (465 aa)
	HGS	Hepatocyte growth factor-regulated tyrosine kinase substrate. (480 aa)
	UBXN6	UBX domain protein 6. (439 aa)
	ATP13A4	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1215 aa)
	SLC29A3	Solute carrier family 29 member 3. (384 aa)
	SLC38A9	Solute carrier family 38 member 9. (561 aa)
	CHMP5	Charged multivesicular body protein 5. (220 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3AXK0_LATCH	LAMTOR2	ENSLACP00000014371	ENSLACP00000012406	Uncharacterized protein.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	0.999
H3AXK0_LATCH	LAMTOR3	ENSLACP00000014371	ENSLACP00000005133	Uncharacterized protein.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	0.999
H3AXK0_LATCH	LAMTOR4	ENSLACP00000014371	ENSLACP00000004196	Uncharacterized protein.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	0.999
H3AXK0_LATCH	LAMTOR5	ENSLACP00000014371	ENSLACP00000020960	Uncharacterized protein.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5.	0.999
H3AXK0_LATCH	SLC38A9	ENSLACP00000014371	ENSLACP00000006212	Uncharacterized protein.	Solute carrier family 38 member 9.	0.997
H3B7E6_LATCH	HGS	ENSLACP00000017817	ENSLACP00000022746	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.929
HGS	H3B7E6_LATCH	ENSLACP00000022746	ENSLACP00000017817	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Uncharacterized protein.	0.929
LAMTOR2	H3AXK0_LATCH	ENSLACP00000012406	ENSLACP00000014371	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	Uncharacterized protein.	0.999
LAMTOR2	LAMTOR3	ENSLACP00000012406	ENSLACP00000005133	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	0.999
LAMTOR2	LAMTOR4	ENSLACP00000012406	ENSLACP00000004196	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	0.999
LAMTOR2	LAMTOR5	ENSLACP00000012406	ENSLACP00000020960	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5.	0.999
LAMTOR2	SLC38A9	ENSLACP00000012406	ENSLACP00000006212	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	Solute carrier family 38 member 9.	0.999
LAMTOR3	H3AXK0_LATCH	ENSLACP00000005133	ENSLACP00000014371	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	Uncharacterized protein.	0.999
LAMTOR3	LAMTOR2	ENSLACP00000005133	ENSLACP00000012406	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	0.999
LAMTOR3	LAMTOR4	ENSLACP00000005133	ENSLACP00000004196	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	0.989
LAMTOR3	LAMTOR5	ENSLACP00000005133	ENSLACP00000020960	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5.	0.999
LAMTOR3	SLC38A9	ENSLACP00000005133	ENSLACP00000006212	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	Solute carrier family 38 member 9.	0.999
LAMTOR4	H3AXK0_LATCH	ENSLACP00000004196	ENSLACP00000014371	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	Uncharacterized protein.	0.999
LAMTOR4	LAMTOR2	ENSLACP00000004196	ENSLACP00000012406	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.	0.999
LAMTOR4	LAMTOR3	ENSLACP00000004196	ENSLACP00000005133	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.	0.989