(84 nodes) Organelle outer membrane network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYNJ2BP	PDZ domain-containing protein. (107 aa)
	SYNE3	Spectrin repeat containing nuclear envelope family member 3. (977 aa)
	PGRMC1	Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (179 aa)
	LRRK2	Leucine rich repeat kinase 2. (2508 aa)
	MIEF1	Mitochondrial elongation factor 1. (548 aa)
	MSTO1	Misato mitochondrial distribution and morphology regulator 1. (555 aa)
	SIGMAR1	Sigma non-opioid intracellular receptor 1. (223 aa)
	CISD2	CDGSH iron sulfur domain 2. (134 aa)
	PLD6	Phospholipase D family member 6. (218 aa)
	LOC102352912	Uncharacterized protein. (209 aa)
	TOMM22	Translocase of outer mitochondrial membrane 22. (104 aa)
	MFN2	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
	PODN	Podocan. (621 aa)
	TOMM34	Translocase of outer mitochondrial membrane 34. (316 aa)
	TOMM70	Translocase of outer mitochondrial membrane 70. (601 aa)
	MTX2	Metaxin 2. (271 aa)
	SPART	Spartin. (664 aa)
	GDAP1L1	Ganglioside induced differentiation associated protein 1 like 1. (365 aa)
	MARCHF5	Membrane associated ring-CH-type finger 5. (280 aa)
	USP30	Ubiquitin carboxyl-terminal hydrolase. (473 aa)
	HAX1	HCLS1 associated protein X-1. (249 aa)
	BNIP3	BCL2 interacting protein 3. (202 aa)
	MFSD11	Major facilitator superfamily domain containing 11. (446 aa)
	GDAP1	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (355 aa)
	SMPD4	Sphingomyelin phosphodiesterase 4. (859 aa)
	NECTIN2	Nectin cell adhesion molecule 2. (502 aa)
	PODNL1	Podocan like 1. (599 aa)
	TOMM40	Translocase of outer mitochondrial membrane 40. (338 aa)
	H3B365_LATCH	Uncharacterized protein. (193 aa)
	TOMM20	Translocase of outer mitochondrial membrane 20. (145 aa)
	FUNDC2	FUN14 domain containing 2. (168 aa)
	MTX3	Metaxin. (320 aa)
	MFN1	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (741 aa)
	RTN4IP1	Reticulon 4 interacting protein 1. (358 aa)
	DNAJC11	DnaJ heat shock protein family (Hsp40) member C11. (564 aa)
	DHCR7	7-dehydrocholesterol reductase. (478 aa)
	LOC102362671	Membrane-associated ring finger (C3HC4) 5, like. (286 aa)
	FAM210B	Family with sequence similarity 210 member B. (163 aa)
	RHOT1	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (673 aa)
	TSPO	Translocator protein. (164 aa)
	MYO19	Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (959 aa)
	SAMM50	SAMM50 sorting and assembly machinery component. (302 aa)
	BNIP3L	BCL2 interacting protein 3 like. (208 aa)
	PINK1	PTEN induced kinase 1. (467 aa)
	LOC102357427	Spermatogenesis associated 18. (325 aa)
	LOC102348870	Zgc:109986. (301 aa)
	RHOT2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (589 aa)
	CISD1	Zgc:110843. (108 aa)
	TIGAR	TP53 induced glycolysis regulatory phosphatase. (212 aa)
	ITPRIP	Inositol 1,4,5-trisphosphate receptor interacting protein. (546 aa)
	H3AAF5_LATCH	GLTP domain-containing protein. (177 aa)
	BCL2L2	BCL2 like 2. (189 aa)
	GPAT2	Glycerol-3-phosphate acyltransferase 2, mitochondrial. (791 aa)
	SARM1	Sterile alpha and TIR motif containing 1. (715 aa)
	MTX1	Metaxin. (321 aa)
	H3AEB8_LATCH	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (147 aa)
	CPT1B	Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (729 aa)
	SPIRE1	Spire type actin nucleation factor 1. (535 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (854 aa)
	KMO	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (474 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2. (620 aa)
	LOC102349352	Amine oxidase. (418 aa)
	MIEF2	Mitochondrial elongation factor 2. (464 aa)
	LOC102348880	KIND domain-containing protein. (635 aa)
	CPT1A	Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
	CPTP	Ceramide-1-phosphate transfer protein. (216 aa)
	MUL1	Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
	MAOB	Amine oxidase. (522 aa)
	TOMM40L	Translocase of outer mitochondrial membrane 40 like. (318 aa)
	VAT1	Vesicle amine transport 1. (414 aa)
	MFF	Mitochondrial fission factor. (345 aa)
	BAD	Uncharacterized protein. (175 aa)
	ITPRIPL2	ITPRIP like 2. (504 aa)
	LOC102360103	Uncharacterized protein. (172 aa)
	LOC102367579	Translocator protein 2. (163 aa)
	CFAP70	Cilia and flagella associated protein 70. (1141 aa)
	LOC106703932	Amine oxidase. (529 aa)
	ITPRIPL1	ITPRIP like 1. (534 aa)
	LOC102358478	Uncharacterized protein. (429 aa)
	SLC25A46	Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (414 aa)
	SFXN2	Sidoreflexin. (323 aa)
	LOC102354722	Uncharacterized protein. (116 aa)
	H3APB7_LATCH	Mitochondrial E3 ubiquitin protein ligase 1a. (243 aa)
	FUNDC1	FUN14 domain containing 1. (152 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAD	BCL2L2	ENSLACP00000011265	ENSLACP00000006748	Uncharacterized protein.	BCL2 like 2.	0.830
BCL2L2	BAD	ENSLACP00000006748	ENSLACP00000011265	BCL2 like 2.	Uncharacterized protein.	0.830
BCL2L2	MFN1	ENSLACP00000006748	ENSLACP00000017343	BCL2 like 2.	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.493
BCL2L2	MFN2	ENSLACP00000006748	ENSLACP00000005825	BCL2 like 2.	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.493
BNIP3	BNIP3L	ENSLACP00000014880	ENSLACP00000020113	BCL2 interacting protein 3.	BCL2 interacting protein 3 like.	0.705
BNIP3	FUNDC1	ENSLACP00000014880	ENSLACP00000011607	BCL2 interacting protein 3.	FUN14 domain containing 1.	0.674
BNIP3	FUNDC2	ENSLACP00000014880	ENSLACP00000016668	BCL2 interacting protein 3.	FUN14 domain containing 2.	0.418
BNIP3	LOC102354722	ENSLACP00000014880	ENSLACP00000003501	BCL2 interacting protein 3.	Uncharacterized protein.	0.901
BNIP3	PINK1	ENSLACP00000014880	ENSLACP00000020138	BCL2 interacting protein 3.	PTEN induced kinase 1.	0.556
BNIP3L	BNIP3	ENSLACP00000020113	ENSLACP00000014880	BCL2 interacting protein 3 like.	BCL2 interacting protein 3.	0.705
BNIP3L	FUNDC1	ENSLACP00000020113	ENSLACP00000011607	BCL2 interacting protein 3 like.	FUN14 domain containing 1.	0.685
BNIP3L	FUNDC2	ENSLACP00000020113	ENSLACP00000016668	BCL2 interacting protein 3 like.	FUN14 domain containing 2.	0.472
BNIP3L	LOC102354722	ENSLACP00000020113	ENSLACP00000003501	BCL2 interacting protein 3 like.	Uncharacterized protein.	0.709
BNIP3L	PINK1	ENSLACP00000020113	ENSLACP00000020138	BCL2 interacting protein 3 like.	PTEN induced kinase 1.	0.523
CFAP70	H3APB7_LATCH	ENSLACP00000023284	ENSLACP00000011488	Cilia and flagella associated protein 70.	Mitochondrial E3 ubiquitin protein ligase 1a.	0.461
CFAP70	LOC102348870	ENSLACP00000023284	ENSLACP00000020393	Cilia and flagella associated protein 70.	Zgc:109986.	0.631
CFAP70	MFN1	ENSLACP00000023284	ENSLACP00000017343	Cilia and flagella associated protein 70.	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.658
CFAP70	MFN2	ENSLACP00000023284	ENSLACP00000005825	Cilia and flagella associated protein 70.	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.658
CFAP70	MUL1	ENSLACP00000023284	ENSLACP00000022155	Cilia and flagella associated protein 70.	Mitochondrial E3 ubiquitin protein ligase 1.	0.461
CFAP70	MYO19	ENSLACP00000023284	ENSLACP00000019811	Cilia and flagella associated protein 70.	Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.651