(34 nodes) Pigment granule network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAB38-2	RAB38b, member of RAS oncogene family. (79 aa)
	RAB38	RAB38b, member of RAS oncogene family. (112 aa)
	PDIA6	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (451 aa)
	TYRP1	Tyrosinase related protein 1. (536 aa)
	TMEM33	Transmembrane protein 33. (245 aa)
	SLC45A4	Solute carrier family 45 member 4. (691 aa)
	H3A523_LATCH	Si:dkey-266m15.6. (2232 aa)
	SLC45A1	Solute carrier family 45 member 1. (770 aa)
	TFRC	Transferrin receptor. (778 aa)
	CNP	2',3'-cyclic nucleotide 3' phosphodiesterase. (423 aa)
	LOC102361629	Uncharacterized protein. (416 aa)
	MREG	Uncharacterized protein. (186 aa)
	TYR	Tyrosinase. (532 aa)
	DCT	Dopachrome tautomerase. (521 aa)
	LOC102360588	Uncharacterized protein. (214 aa)
	TFR2	Transferrin receptor 2. (728 aa)
	H3AUJ0_LATCH	G_PROTEIN_RECEP_F1_2 domain-containing protein. (341 aa)
	ERICH3	Uncharacterized protein. (705 aa)
	GPNMB	Glycoprotein nmb. (607 aa)
	RAB32	Uncharacterized protein. (174 aa)
	CTNS	Cystinosin, lysosomal cystine transporter. (340 aa)
	LOC102360616	C-reactive protein 2. (274 aa)
	PMEL	Premelanosome protein. (766 aa)
	GPR143	G protein-coupled receptor 143. (413 aa)
	ABCB6	ATP binding cassette subfamily B member 6 (Langereis blood group). (776 aa)
	LOC102359814	Uncharacterized protein. (719 aa)
	ANXA6	Annexin. (662 aa)
	GCHFR	GTP cyclohydrolase I feedback regulator. (88 aa)
	SYTL2	Synaptotagmin like 2. (720 aa)
	H3B8F0_LATCH	Uncharacterized protein. (378 aa)
	LOC102366418	Zgc:91968. (232 aa)
	MFSD12	Major facilitator superfamily domain containing 12. (491 aa)
	SYTL1	Synaptotagmin like 1. (418 aa)
	SLC45A2	Solute carrier family 45 member 2. (411 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB6	TFRC	ENSLACP00000020225	ENSLACP00000008904	ATP binding cassette subfamily B member 6 (Langereis blood group).	Transferrin receptor.	0.409
CTNS	MFSD12	ENSLACP00000023270	ENSLACP00000017375	Cystinosin, lysosomal cystine transporter.	Major facilitator superfamily domain containing 12.	0.426
DCT	MREG	ENSLACP00000011443	ENSLACP00000010156	Dopachrome tautomerase.	Uncharacterized protein.	0.501
DCT	PMEL	ENSLACP00000011443	ENSLACP00000021576	Dopachrome tautomerase.	Premelanosome protein.	0.751
DCT	RAB38	ENSLACP00000011443	ENSLACP00000000658	Dopachrome tautomerase.	RAB38b, member of RAS oncogene family.	0.515
DCT	RAB38-2	ENSLACP00000011443	ENSLACP00000014829	Dopachrome tautomerase.	RAB38b, member of RAS oncogene family.	0.412
DCT	SLC45A2	ENSLACP00000011443	ENSLACP00000015816	Dopachrome tautomerase.	Solute carrier family 45 member 2.	0.639
DCT	TYR	ENSLACP00000011443	ENSLACP00000011256	Dopachrome tautomerase.	Tyrosinase.	0.797
DCT	TYRP1	ENSLACP00000011443	ENSLACP00000002347	Dopachrome tautomerase.	Tyrosinase related protein 1.	0.943
GCHFR	GPNMB	ENSLACP00000018768	ENSLACP00000014171	GTP cyclohydrolase I feedback regulator.	Glycoprotein nmb.	0.437
GCHFR	GPR143	ENSLACP00000018768	ENSLACP00000014610	GTP cyclohydrolase I feedback regulator.	G protein-coupled receptor 143.	0.418
GCHFR	TYRP1	ENSLACP00000018768	ENSLACP00000002347	GTP cyclohydrolase I feedback regulator.	Tyrosinase related protein 1.	0.464
GPNMB	GCHFR	ENSLACP00000014171	ENSLACP00000018768	Glycoprotein nmb.	GTP cyclohydrolase I feedback regulator.	0.437
GPNMB	TYRP1	ENSLACP00000014171	ENSLACP00000002347	Glycoprotein nmb.	Tyrosinase related protein 1.	0.469
GPR143	GCHFR	ENSLACP00000014610	ENSLACP00000018768	G protein-coupled receptor 143.	GTP cyclohydrolase I feedback regulator.	0.418
GPR143	PMEL	ENSLACP00000014610	ENSLACP00000021576	G protein-coupled receptor 143.	Premelanosome protein.	0.452
GPR143	SLC45A2	ENSLACP00000014610	ENSLACP00000015816	G protein-coupled receptor 143.	Solute carrier family 45 member 2.	0.638
GPR143	TYR	ENSLACP00000014610	ENSLACP00000011256	G protein-coupled receptor 143.	Tyrosinase.	0.709
GPR143	TYRP1	ENSLACP00000014610	ENSLACP00000002347	G protein-coupled receptor 143.	Tyrosinase related protein 1.	0.753
H3AUJ0_LATCH	TYR	ENSLACP00000013311	ENSLACP00000011256	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Tyrosinase.	0.466