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FRK FRK SH2D4B SH2D4B LOC102354147 LOC102354147 GRB2 GRB2 H2ZTU0_LATCH H2ZTU0_LATCH RIN2 RIN2 LOC102364341 LOC102364341 GRB10 GRB10 BCAR3 BCAR3 CHN1 CHN1 STAP2 STAP2 PTPN6 PTPN6 H2ZZG8_LATCH H2ZZG8_LATCH SOCS5 SOCS5 LOC102348150 LOC102348150 BLNK BLNK TXK TXK BLK BLK SUPT6H SUPT6H LOC102356003 LOC102356003 LCP2 LCP2 DAPP1 DAPP1 LOC102352804 LOC102352804 NCK1 NCK1 SRMS SRMS LOC102355346 LOC102355346 RASA1 RASA1 H3A744_LATCH H3A744_LATCH SHD SHD GRB14 GRB14 ABL2 ABL2 LYN LYN SOCS2 SOCS2 SOCS6 SOCS6 JAK2 JAK2 PTPN11 PTPN11 SRC SRC STAT1 STAT1 SH2D6 SH2D6 SHC2 SHC2 SH2B1 SH2B1 ZAP70 ZAP70 LOC102348007 LOC102348007 CSK CSK SOCS1 SOCS1 H3AL82_LATCH H3AL82_LATCH NCK2 NCK2 LOC102362993 LOC102362993 SH2D4A SH2D4A SHC3 SHC3 TNS1 TNS1 CRK CRK GRAP2 GRAP2 SHC1 SHC1 LOC102360670 LOC102360670 SYK SYK H3ATR3_LATCH H3ATR3_LATCH RIN1 RIN1 STAT3 STAT3 SHC4 SHC4 TNS3 TNS3 LOC102366450 LOC102366450 TNS4 TNS4 FYN FYN LCK LCK MATK MATK SH2B3 SH2B3 H3AZT3_LATCH H3AZT3_LATCH LOC102351582 LOC102351582 LOC102363504 LOC102363504 PIK3R1 PIK3R1 SH2D3C SH2D3C GRB7 GRB7 SH3BP2 SH3BP2 ITK ITK STAP1 STAP1 SHE SHE SH2D3A SH2D3A ABL1 ABL1 FES FES YES1 YES1 CHN2 CHN2 FGR FGR TNS2 TNS2 BTK BTK SOCS3 SOCS3 SH2B2 SH2B2 CISH CISH RINL RINL RAB8A RAB8A SLA2 SLA2 SH2D5 SH2D5 SOCS7 SOCS7 LOC102352712 LOC102352712 PLCG1 PLCG1 STAT2 STAT2 RIN3 RIN3 BMX BMX SHF SHF SH2D1A SH2D1A SLA SLA TEC TEC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FRKTyrosine-protein kinase. (782 aa)
SH2D4BSH2 domain containing 4B. (376 aa)
LOC102354147Uncharacterized protein. (201 aa)
GRB2Growth factor receptor bound protein 2. (292 aa)
H2ZTU0_LATCHSH2 domain-containing protein. (115 aa)
RIN2Ras and Rab interactor 2. (902 aa)
LOC102364341Uncharacterized protein. (271 aa)
GRB10Growth factor receptor bound protein 10. (433 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (721 aa)
CHN1SH2 domain-containing protein. (197 aa)
STAP2Uncharacterized protein. (263 aa)
PTPN6Protein tyrosine phosphatase non-receptor type 6. (338 aa)
H2ZZG8_LATCHTyrosine-protein kinase. (396 aa)
SOCS5Suppressor of cytokine signaling 5. (538 aa)
LOC102348150Signal transducer and activator of transcription. (786 aa)
BLNKB cell linker. (546 aa)
TXKTyrosine-protein kinase. (426 aa)
BLKTyrosine-protein kinase. (447 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1719 aa)
LOC102356003SH2 domain-containing protein. (170 aa)
LCP2Lymphocyte cytosolic protein 2. (518 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (245 aa)
LOC102352804Phosphoinositide phospholipase C. (1172 aa)
NCK1Cytoplasmic protein. (377 aa)
SRMSTyrosine-protein kinase. (497 aa)
LOC102355346SH2 domain-containing protein. (183 aa)
RASA1RAS p21 protein activator 1. (878 aa)
H3A744_LATCHTyrosine-protein kinase. (461 aa)
SHDSrc homology 2 domain containing transforming protein D. (321 aa)
GRB14Growth factor receptor bound protein 14. (453 aa)
ABL2Tyrosine-protein kinase. (1175 aa)
LYNTyrosine-protein kinase. (515 aa)
SOCS2Suppressor of cytokine signaling 2. (176 aa)
SOCS6Suppressor of cytokine signaling 6. (536 aa)
JAK2Tyrosine-protein kinase. (1152 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (586 aa)
SRCTyrosine-protein kinase. (535 aa)
STAT1Signal transducer and activator of transcription. (1179 aa)
SH2D6SH2 domain-containing protein. (105 aa)
SHC2SHC (Src homology 2 domain containing) transforming protein 2. (633 aa)
SH2B1SH2B adaptor protein 1. (637 aa)
ZAP70Tyrosine-protein kinase. (609 aa)
LOC102348007Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (392 aa)
CSKTyrosine-protein kinase. (452 aa)
SOCS1Suppressor of cytokine signaling 1a. (190 aa)
H3AL82_LATCHUncharacterized protein. (245 aa)
NCK2Cytoplasmic protein. (380 aa)
LOC102362993Uncharacterized protein. (202 aa)
SH2D4ASH2 domain containing 4A. (439 aa)
SHC3SHC adaptor protein 3. (630 aa)
TNS1Tensin 1. (1685 aa)
CRKCRK proto-oncogene, adaptor protein. (310 aa)
GRAP2GRB2 related adaptor protein 2. (309 aa)
SHC1SHC adaptor protein 1. (602 aa)
LOC102360670Uncharacterized protein. (209 aa)
SYKTyrosine-protein kinase. (616 aa)
H3ATR3_LATCHSuppressor of cytokine signaling 9. (442 aa)
RIN1SH2 domain-containing protein. (592 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
SHC4SHC adaptor protein 4. (617 aa)
TNS3Tensin 3. (1389 aa)
LOC102366450Uncharacterized protein. (213 aa)
TNS4Tensin 4. (745 aa)
FYNTyrosine-protein kinase. (537 aa)
LCKTyrosine-protein kinase. (512 aa)
MATKTyrosine-protein kinase. (447 aa)
SH2B3SH2B adaptor protein 3. (583 aa)
H3AZT3_LATCHGRB2 related adaptor protein b. (99 aa)
LOC102351582SH2 domain-containing protein. (892 aa)
LOC102363504Tyrosine-protein kinase. (1116 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
SH2D3CSH2 domain containing 3C. (730 aa)
GRB7Growth factor receptor bound protein 7. (436 aa)
SH3BP2SH3 domain binding protein 2. (590 aa)
ITKTyrosine-protein kinase. (624 aa)
STAP1Signal transducing adaptor family member 1. (239 aa)
SHESrc homology 2 domain containing E. (472 aa)
SH2D3ASH2 domain containing 3A. (645 aa)
ABL1Tyrosine-protein kinase. (1156 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa)
YES1Tyrosine-protein kinase. (539 aa)
CHN2Chimerin 2. (420 aa)
FGRTyrosine-protein kinase. (535 aa)
TNS2Tensin 2. (1731 aa)
BTKTyrosine-protein kinase. (646 aa)
SOCS3Suppressor of cytokine signaling 3. (205 aa)
SH2B2SH2B adaptor protein 2. (664 aa)
CISHCytokine inducible SH2 containing protein. (243 aa)
RINLUncharacterized protein. (763 aa)
RAB8ARAB8A, member RAS oncogene family. (598 aa)
SLA2Src like adaptor 2. (259 aa)
SH2D5SH2 domain containing 5. (442 aa)
SOCS7Suppressor of cytokine signaling 7. (485 aa)
LOC102352712Protein tyrosine phosphatase non-receptor type 11b. (553 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1219 aa)
STAT2Signal transducer and activator of transcription. (765 aa)
RIN3Ras and Rab interactor 3. (951 aa)
BMXTyrosine-protein kinase. (677 aa)
SHFSrc homology 2 domain containing F. (419 aa)
SH2D1ASH2 domain containing 1A. (124 aa)
SLASrc like adaptor. (165 aa)
TECTyrosine-protein kinase. (662 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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