(41 nodes) Phox homology network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NOXO1	Uncharacterized protein. (488 aa)
	KIF16B	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1321 aa)
	SNX19	Sorting nexin 19. (856 aa)
	SNX2	Sorting nexin 2. (520 aa)
	SNX27	Sorting nexin 27. (559 aa)
	NCF4	Neutrophil cytosolic factor 4. (360 aa)
	H3A2Y1_LATCH	Uncharacterized protein. (427 aa)
	H3A360_LATCH	PX domain-containing protein. (140 aa)
	PIK3C2G	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1263 aa)
	SNX17	Sorting nexin 17. (455 aa)
	RPS6KC1	Ribosomal protein S6 kinase C1. (1076 aa)
	PXDC1	PX domain containing 1. (231 aa)
	SNX25	Sorting nexin 25. (620 aa)
	SNX16	Sorting nexin 16. (359 aa)
	SNX14	Sorting nexin 14. (945 aa)
	SNX4	Sorting nexin 4. (405 aa)
	SGK3	Non-specific serine/threonine protein kinase. (495 aa)
	PLD1	Phospholipase. (1072 aa)
	SNX18	Sorting nexin. (587 aa)
	SNX12	Sorting nexin 12. (174 aa)
	SNX7	Sorting nexin 7. (426 aa)
	SNX20	Sorting nexin 20. (270 aa)
	SNX11	Sorting nexin 11. (216 aa)
	SH3PXD2B	SH3 and PX domains 2B. (878 aa)
	SNX32	Sorting nexin 32. (412 aa)
	SNX5	Sorting nexin 5. (386 aa)
	PXK	PX domain containing serine/threonine kinase like. (577 aa)
	SH3PXD2A	SH3 and PX domains 2A. (1118 aa)
	SNX30	Sorting nexin family member 30. (513 aa)
	SNX10	Sorting nexin 10. (203 aa)
	SNX22	Sorting nexin 22. (189 aa)
	SNX3	Sorting nexin 3. (108 aa)
	SNX1	PX domain-containing protein. (510 aa)
	SNX8	Sorting nexin 8. (571 aa)
	SNX9	Sorting nexin 9. (467 aa)
	SNX13	Sorting nexin 13. (960 aa)
	PIK3C2A	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1720 aa)
	NCF1	Neutrophil cytosolic factor 1. (416 aa)
	PIK3C2B	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1652 aa)
	SNX6	Sorting nexin; Involved in several stages of intracellular trafficking. (423 aa)
	SNX21	Sorting nexin family member 21. (365 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3A2Y1_LATCH	NCF1	ENSLACP00000004002	ENSLACP00000019630	Uncharacterized protein.	Neutrophil cytosolic factor 1.	0.511
H3A2Y1_LATCH	NCF4	ENSLACP00000004002	ENSLACP00000003310	Uncharacterized protein.	Neutrophil cytosolic factor 4.	0.420
H3A360_LATCH	SNX11	ENSLACP00000004081	ENSLACP00000012563	PX domain-containing protein.	Sorting nexin 11.	0.459
H3A360_LATCH	SNX2	ENSLACP00000004081	ENSLACP00000002392	PX domain-containing protein.	Sorting nexin 2.	0.434
H3A360_LATCH	SNX22	ENSLACP00000004081	ENSLACP00000017795	PX domain-containing protein.	Sorting nexin 22.	0.558
NCF1	H3A2Y1_LATCH	ENSLACP00000019630	ENSLACP00000004002	Neutrophil cytosolic factor 1.	Uncharacterized protein.	0.511
NCF1	NCF4	ENSLACP00000019630	ENSLACP00000003310	Neutrophil cytosolic factor 1.	Neutrophil cytosolic factor 4.	0.998
NCF1	NOXO1	ENSLACP00000019630	ENSLACP00000001254	Neutrophil cytosolic factor 1.	Uncharacterized protein.	0.511
NCF4	H3A2Y1_LATCH	ENSLACP00000003310	ENSLACP00000004002	Neutrophil cytosolic factor 4.	Uncharacterized protein.	0.420
NCF4	NCF1	ENSLACP00000003310	ENSLACP00000019630	Neutrophil cytosolic factor 4.	Neutrophil cytosolic factor 1.	0.998
NCF4	NOXO1	ENSLACP00000003310	ENSLACP00000001254	Neutrophil cytosolic factor 4.	Uncharacterized protein.	0.420
NOXO1	NCF1	ENSLACP00000001254	ENSLACP00000019630	Uncharacterized protein.	Neutrophil cytosolic factor 1.	0.511
NOXO1	NCF4	ENSLACP00000001254	ENSLACP00000003310	Uncharacterized protein.	Neutrophil cytosolic factor 4.	0.420
PIK3C2A	PIK3C2G	ENSLACP00000019372	ENSLACP00000004519	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family.	0.910
PIK3C2A	SNX1	ENSLACP00000019372	ENSLACP00000018042	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	PX domain-containing protein.	0.517
PIK3C2A	SNX18	ENSLACP00000019372	ENSLACP00000010085	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	Sorting nexin.	0.955
PIK3C2A	SNX2	ENSLACP00000019372	ENSLACP00000002392	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	Sorting nexin 2.	0.517
PIK3C2A	SNX32	ENSLACP00000019372	ENSLACP00000013398	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	Sorting nexin 32.	0.493
PIK3C2A	SNX5	ENSLACP00000019372	ENSLACP00000013497	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	Sorting nexin 5.	0.493
PIK3C2A	SNX6	ENSLACP00000019372	ENSLACP00000020529	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.493