(8 nodes) Death effector domain network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CASP10	Caspase 10; Belongs to the peptidase C14A family. (539 aa)
	DEDD2	Death effector domain containing 2. (372 aa)
	LOC102359774	Uncharacterized protein. (218 aa)
	FADD	Fas associated via death domain. (193 aa)
	DEDD	Death effector domain containing. (354 aa)
	PEA15	Proliferation and apoptosis adaptor protein 15. (133 aa)
	H3A526_LATCH	Uncharacterized protein; Belongs to the peptidase C14A family. (486 aa)
	H3A2R2_LATCH	Uncharacterized protein; Belongs to the peptidase C14A family. (480 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP10	FADD	ENSLACP00000002069	ENSLACP00000009943	Caspase 10; Belongs to the peptidase C14A family.	Fas associated via death domain.	0.996
CASP10	LOC102359774	ENSLACP00000002069	ENSLACP00000017377	Caspase 10; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.991
FADD	CASP10	ENSLACP00000009943	ENSLACP00000002069	Fas associated via death domain.	Caspase 10; Belongs to the peptidase C14A family.	0.996
FADD	H3A2R2_LATCH	ENSLACP00000009943	ENSLACP00000003933	Fas associated via death domain.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.934
FADD	H3A526_LATCH	ENSLACP00000009943	ENSLACP00000004747	Fas associated via death domain.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.934
FADD	LOC102359774	ENSLACP00000009943	ENSLACP00000017377	Fas associated via death domain.	Uncharacterized protein.	0.965
FADD	PEA15	ENSLACP00000009943	ENSLACP00000005163	Fas associated via death domain.	Proliferation and apoptosis adaptor protein 15.	0.674
H3A2R2_LATCH	FADD	ENSLACP00000003933	ENSLACP00000009943	Uncharacterized protein; Belongs to the peptidase C14A family.	Fas associated via death domain.	0.934
H3A2R2_LATCH	LOC102359774	ENSLACP00000003933	ENSLACP00000017377	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.911
H3A526_LATCH	FADD	ENSLACP00000004747	ENSLACP00000009943	Uncharacterized protein; Belongs to the peptidase C14A family.	Fas associated via death domain.	0.934
H3A526_LATCH	LOC102359774	ENSLACP00000004747	ENSLACP00000017377	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.906
LOC102359774	CASP10	ENSLACP00000017377	ENSLACP00000002069	Uncharacterized protein.	Caspase 10; Belongs to the peptidase C14A family.	0.991
LOC102359774	FADD	ENSLACP00000017377	ENSLACP00000009943	Uncharacterized protein.	Fas associated via death domain.	0.965
LOC102359774	H3A2R2_LATCH	ENSLACP00000017377	ENSLACP00000003933	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.911
LOC102359774	H3A526_LATCH	ENSLACP00000017377	ENSLACP00000004747	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.906
PEA15	FADD	ENSLACP00000005163	ENSLACP00000009943	Proliferation and apoptosis adaptor protein 15.	Fas associated via death domain.	0.674