(20 nodes) Glycosyl hydrolase, all-beta network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FUCA1	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (464 aa)
	SLC3A1	Solute carrier family 3 member 1. (681 aa)
	LOC102366792	Si:ch73-12o23.1; Belongs to the glycosyl hydrolase 31 family. (856 aa)
	MAN2B1	Alpha-mannosidase. (973 aa)
	MAN2A2	Alpha-mannosidase. (1152 aa)
	GANAB	Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family. (942 aa)
	GAA	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (888 aa)
	GLA	Alpha-galactosidase. (416 aa)
	LOC102352322	Aamy domain-containing protein. (520 aa)
	LOC102359920	Si:ch211-236l14.4; Belongs to the glycosyl hydrolase 31 family. (690 aa)
	LOC102365271	Alpha-amylase. (515 aa)
	H3A9B7_LATCH	Uncharacterized protein. (521 aa)
	LOC102361487	Alpha-galactosidase. (370 aa)
	LOC102366389	Alpha-galactosidase. (407 aa)
	MYORG	Myogenesis regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family. (656 aa)
	GBE1	1,4-alpha-glucan branching enzyme 1. (686 aa)
	MAN2B2	Alpha-mannosidase. (890 aa)
	SI	Uncharacterized protein. (1851 aa)
	MAN2A1	Alpha-mannosidase. (826 aa)
	GANC	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (916 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FUCA1	GLA	ENSLACP00000011487	ENSLACP00000019727	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.	Alpha-galactosidase.	0.451
FUCA1	LOC102361487	ENSLACP00000011487	ENSLACP00000006979	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.	Alpha-galactosidase.	0.420
GBE1	H3A9B7_LATCH	ENSLACP00000011426	ENSLACP00000006238	1,4-alpha-glucan branching enzyme 1.	Uncharacterized protein.	0.722
GBE1	LOC102352322	ENSLACP00000011426	ENSLACP00000023504	1,4-alpha-glucan branching enzyme 1.	Aamy domain-containing protein.	0.722
GBE1	LOC102365271	ENSLACP00000011426	ENSLACP00000005390	1,4-alpha-glucan branching enzyme 1.	Alpha-amylase.	0.970
GBE1	SI	ENSLACP00000011426	ENSLACP00000002742	1,4-alpha-glucan branching enzyme 1.	Uncharacterized protein.	0.932
GBE1	SLC3A1	ENSLACP00000011426	ENSLACP00000011899	1,4-alpha-glucan branching enzyme 1.	Solute carrier family 3 member 1.	0.722
GLA	FUCA1	ENSLACP00000019727	ENSLACP00000011487	Alpha-galactosidase.	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.	0.451
GLA	MAN2B1	ENSLACP00000019727	ENSLACP00000016733	Alpha-galactosidase.	Alpha-mannosidase.	0.404
GLA	MAN2B2	ENSLACP00000019727	ENSLACP00000000149	Alpha-galactosidase.	Alpha-mannosidase.	0.404
GLA	SI	ENSLACP00000019727	ENSLACP00000002742	Alpha-galactosidase.	Uncharacterized protein.	0.922
H3A9B7_LATCH	GBE1	ENSLACP00000006238	ENSLACP00000011426	Uncharacterized protein.	1,4-alpha-glucan branching enzyme 1.	0.722
H3A9B7_LATCH	SLC3A1	ENSLACP00000006238	ENSLACP00000011899	Uncharacterized protein.	Solute carrier family 3 member 1.	0.482
LOC102352322	GBE1	ENSLACP00000023504	ENSLACP00000011426	Aamy domain-containing protein.	1,4-alpha-glucan branching enzyme 1.	0.722
LOC102361487	FUCA1	ENSLACP00000006979	ENSLACP00000011487	Alpha-galactosidase.	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.	0.420
LOC102361487	LOC102366389	ENSLACP00000006979	ENSLACP00000007293	Alpha-galactosidase.	Alpha-galactosidase.	0.902
LOC102361487	MAN2B1	ENSLACP00000006979	ENSLACP00000016733	Alpha-galactosidase.	Alpha-mannosidase.	0.404
LOC102361487	MAN2B2	ENSLACP00000006979	ENSLACP00000000149	Alpha-galactosidase.	Alpha-mannosidase.	0.404
LOC102365271	GBE1	ENSLACP00000005390	ENSLACP00000011426	Alpha-amylase.	1,4-alpha-glucan branching enzyme 1.	0.970
LOC102365271	SI	ENSLACP00000005390	ENSLACP00000002742	Alpha-amylase.	Uncharacterized protein.	0.936