(48 nodes) Pyridoxal phosphate-dependent transferase network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102354530	Aminotran_1_2 domain-containing protein. (422 aa)
	NFS1	NFS1 cysteine desulfurase. (449 aa)
	ALAS1	5-aminolevulinate synthase. (642 aa)
	HDC	Histidine decarboxylase. (666 aa)
	LOC102346865	Threonine aldolase 1. (417 aa)
	LOC102362620	Aminotran_1_2 domain-containing protein. (891 aa)
	CSAD	Uncharacterized protein. (491 aa)
	KYAT1	Kynurenine aminotransferase 1. (457 aa)
	OAT	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
	PHYKPL	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
	ETNPPL	Ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (524 aa)
	SPTLC3	Serine palmitoyltransferase long chain base subunit 3. (551 aa)
	ALAS2	5-aminolevulinate synthase. (615 aa)
	SPTLC2	Serine palmitoyltransferase long chain base subunit 2. (532 aa)
	GOT1	Aspartate aminotransferase. (399 aa)
	GAD1	Glutamate decarboxylase 1. (590 aa)
	PDXDC1	Pyridoxal dependent decarboxylase domain containing 1. (801 aa)
	SGPL1	Sphingosine-1-phosphate lyase 1. (566 aa)
	MOCOS	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (800 aa)
	SCLY	Selenocysteine lyase. (381 aa)
	GAD2	Glutamate decarboxylase 2. (476 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (474 aa)
	KYAT3	Kynurenine aminotransferase 3. (456 aa)
	DDC	Dopa decarboxylase. (503 aa)
	GLDC	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (914 aa)
	KYNU	Kynureninase. (278 aa)
	GADL1	Glutamate decarboxylase like 1. (519 aa)
	SPTLC1	Serine palmitoyltransferase long chain base subunit 1. (472 aa)
	AGXT	Serine--pyruvate aminotransferase. (426 aa)
	ABAT	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (490 aa)
	LOC102358421	Uncharacterized protein. (548 aa)
	LOC102367556	Uncharacterized protein. (341 aa)
	LOC102345272	Phosphoserine aminotransferase. (368 aa)
	AGXT2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa)
	GOT1L1	Glutamic-oxaloacetic transaminase 1 like 1. (405 aa)
	AADAT	Aminoadipate aminotransferase. (425 aa)
	CTH	Uncharacterized protein. (410 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (542 aa)
	TAT	Tyrosine aminotransferase. (183 aa)
	H2ZXP4_LATCH	Uncharacterized protein. (727 aa)
	LOC102346076	Aminotran_5 domain-containing protein. (349 aa)
	LOC102360660	Aminotran_5 domain-containing protein. (368 aa)
	GOT2	Aspartate aminotransferase. (392 aa)
	SEPSECS	O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. (492 aa)
	LOC102361787	Aminotran_1_2 domain-containing protein. (285 aa)
	GCAT	Glycine C-acetyltransferase. (311 aa)
	H2ZS89_LATCH	Uncharacterized protein. (189 aa)
	GPT2	Glutamic--pyruvic transaminase 2. (484 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADAT	ABAT	ENSLACP00000003451	ENSLACP00000006938	Aminoadipate aminotransferase.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.465
AADAT	AGXT	ENSLACP00000003451	ENSLACP00000007350	Aminoadipate aminotransferase.	Serine--pyruvate aminotransferase.	0.511
AADAT	AGXT2	ENSLACP00000003451	ENSLACP00000004295	Aminoadipate aminotransferase.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.511
AADAT	ETNPPL	ENSLACP00000003451	ENSLACP00000017133	Aminoadipate aminotransferase.	Ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.465
AADAT	GOT1	ENSLACP00000003451	ENSLACP00000015852	Aminoadipate aminotransferase.	Aspartate aminotransferase.	0.453
AADAT	GOT1L1	ENSLACP00000003451	ENSLACP00000023621	Aminoadipate aminotransferase.	Glutamic-oxaloacetic transaminase 1 like 1.	0.453
AADAT	GOT2	ENSLACP00000003451	ENSLACP00000001398	Aminoadipate aminotransferase.	Aspartate aminotransferase.	0.603
AADAT	KYAT1	ENSLACP00000003451	ENSLACP00000017715	Aminoadipate aminotransferase.	Kynurenine aminotransferase 1.	0.943
AADAT	KYAT3	ENSLACP00000003451	ENSLACP00000011017	Aminoadipate aminotransferase.	Kynurenine aminotransferase 3.	0.943
AADAT	KYNU	ENSLACP00000003451	ENSLACP00000023152	Aminoadipate aminotransferase.	Kynureninase.	0.956
AADAT	OAT	ENSLACP00000003451	ENSLACP00000017508	Aminoadipate aminotransferase.	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.458
AADAT	PHYKPL	ENSLACP00000003451	ENSLACP00000017347	Aminoadipate aminotransferase.	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.465
ABAT	AADAT	ENSLACP00000006938	ENSLACP00000003451	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aminoadipate aminotransferase.	0.465
ABAT	AGXT	ENSLACP00000006938	ENSLACP00000007350	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Serine--pyruvate aminotransferase.	0.648
ABAT	AGXT2	ENSLACP00000006938	ENSLACP00000004295	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.939
ABAT	CSAD	ENSLACP00000006938	ENSLACP00000018991	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Uncharacterized protein.	0.505
ABAT	DDC	ENSLACP00000006938	ENSLACP00000010396	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Dopa decarboxylase.	0.439
ABAT	GAD1	ENSLACP00000006938	ENSLACP00000014477	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase 1.	0.950
ABAT	GAD2	ENSLACP00000006938	ENSLACP00000011184	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase 2.	0.505
ABAT	GADL1	ENSLACP00000006938	ENSLACP00000023283	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase like 1.	0.948